LEADER 03911oam  2200637I  450 
001 9910827674403321
005 20230803025737.0
010   $a0-429-16585-4
010   $a1-4398-6258-3
024 7 $a10.1201/b14166 
035   $a(CKB)2670000000341598
035   $a(EBL)1153191
035   $a(OCoLC)831118576
035   $a(SSID)ssj0000835126
035   $a(PQKBManifestationID)11462241
035   $a(PQKBTitleCode)TC0000835126
035   $a(PQKBWorkID)10989673
035   $a(PQKB)11457115
035   $a(MiAaPQ)EBC1153191
035   $a(Au-PeEL)EBL1153191
035   $a(CaPaEBR)ebr10674487
035   $a(CaONFJC)MIL502263
035   $a(EXLCZ)992670000000341598
100   $a20180331d2013      uy             0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 00$aConnexin cell communication channels $eroles in the immune system and immunopathology /$fedited by Ernesto Oviedo-Orta, Brenda R. Kwak, William Howard Evans
210  1$aBoca Raton :$cTaylor & Francis/CRC Press,$d2013.
215   $a1 online resource (363 p.)
300   $aDescription based upon print version of record.
311   $a1-4398-6257-5 
320   $aIncludes bibliographical references.
327   $aFront Cover; Contents; Preface; Editors; Contributors; Prequel: Gap Junctions, Hemichannels, and Cell-to-Cell Signalling; Chapter 1 - Communication in the Immune System by Connexin Channels; Chapter 2 - Gap Junctions and Connexins in the Hematopoietic-Immune System: Structural Considerations; Chapter 3 - Approaches for Studying the Role(s) of Gap Junctions in the Immune System; Chapter 4 - Gap Junctions in Antigen-Presenting Cells; Chapter 5 - Connect the Immune System: Roles of Gap Junctions in Antigen Presentation and T Cell Activation
327   $aChapter 6 - Gap Junctions and Connexins in the Immune Defense Against TumorsChapter 7 - Connexins in Atherosclerosis; Chapter 8 - Connexins in Lung Function and Inflammation; Chapter 9 - Effect of Oxidative Stress on Connexins in the Vasculature; Chapter 10 - Regulation of Gap Junctions and Cellular Coupling within the Microvasculature in Response to Acute Inflammation; Chapter 11 - Impact of Microglial Activation on Astroglial Connexin Expression and Function in Brain Inflammation; Chapter 12 - A Role for Connexins in Inflammatory Disorders of the Epidermis
327   $aChapter 13 - Translating Basic Research on Cx43 Gap Junctions into Therapies for Reducing Scarring and Cardiac ArrhythmiaChapter 14 - Connexin-Based Therapeutic Approaches to Inflammation in the Central Nervous System; Chapter 15 - Enhancing Epithelial Tissue Repair and Reducing Inflammation by Targeting Connexins; Back Cover
330   $aPlasma membrane-associated channels known as gap junctions, along with their protein building blocks-connexins-have an important functional role in a range of immunological processes, including heart function, cell growth and specialization, and early development. Spanning basic science and potential clinical applications, Connexin Cell Communication Channels: Roles in the Immune System and Immunopathology assembles and synthesizes four decades of the most important research carried out in this field. The book first provides a historical overview of the discovery of these membrane channels in 
606   $aGap junctions (Cell biology)
606   $aConnexins
606   $aInflammation
615  0$aGap junctions (Cell biology)
615  0$aConnexins.
615  0$aInflammation.
676   $a591.876041
701   $aOviedo-Orta$b Ernesto$01683231
701   $aKwak$b Brenda R$01683232
701   $aEvans$b W. Howard$0531435
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910827674403321
996   $aConnexin cell communication channels$94053886
997   $aUNINA