LEADER 03038nam 2200661Ia 450 001 9910826813103321 005 20230313144946.0 010 $a1-4443-5666-6 010 $a1-282-13959-2 010 $a9786612139598 010 $a1-4443-1172-7 010 $a1-4443-1171-9 035 $a(CKB)1000000000719878 035 $a(EBL)428204 035 $a(OCoLC)476273032 035 $a(SSID)ssj0000128308 035 $a(PQKBManifestationID)11138734 035 $a(PQKBTitleCode)TC0000128308 035 $a(PQKBWorkID)10063963 035 $a(PQKB)11476455 035 $a(MiAaPQ)EBC428204 035 $a(MiAaPQ)EBC4041828 035 $a(Au-PeEL)EBL428204 035 $a(CaPaEBR)ebr10308186 035 $a(Au-PeEL)EBL4041828 035 $a(CaPaEBR)ebr11114601 035 $a(CaONFJC)MIL213959 035 $a(OCoLC)958540296 035 $a(EXLCZ)991000000000719878 100 $a20081229d2009 uy 0 101 0 $aeng 135 $aurcn||||||||| 181 $ctxt 182 $cc 183 $acr 200 12$aA concise guide to clinical trials 205 $a1st ed. 210 $aOxford $cWiley-Blackwell$dc2009 215 $a1 online resource (225 p.) 300 $aDescription based upon print version of record. 311 $a1-4051-6774-2 320 $aIncludes bibliographical references and index. 327 $aA Concise Guide to Clinical Trials; Contents; Preface; Foreword; 1 Fundamental concepts; 2 Types of outcome measures and understanding them; 3 Design and analysis of phase I trials; 4 Design and analysis of phase II trials; 5 Design of phase III trials; 6 Randomisation; 7 Analysis and interpretation of phase III trials; 8 Systematic reviews and meta-analyses; 9 Health-related quality of life and health economic evaluation; 10 Setting up, conducting and reporting trials; 11 Regulations and guidelines; Reading list; Statistical formulae for calculating some 95% confidence intervals; Index 330 $aClinical trials have revolutionized the way disease is prevented, detected and treated, and early death avoided, and they continue to be an expanding area of research. They are central to the work of pharmaceutical companies, and there are many academic and public sector organizations that conduct trials on a wide variety of interventions, including drugs, devices, surgical techniques, and changes in behaviour and lifestyle. A Concise Guide to Clinical Trials provides a comprehensive yet easy-to-read overview of the design, conduct and analysis of trials. It requires no prior 606 $aClinical trials$vHandbooks, manuals, etc 606 $aClinical medicine$xResearch$vHandbooks, manuals, etc 615 0$aClinical trials 615 0$aClinical medicine$xResearch 676 $a615.19 676 $a615.50724 700 $aHackshaw$b Allan K$0868857 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910826813103321 996 $aA concise guide to clinical trials$93945085 997 $aUNINA