LEADER 03472nam 22007214a 450 001 9910826499703321 005 20200520144314.0 010 $a1-107-13477-3 010 $a1-280-15976-6 010 $a9786610159765 010 $a0-511-12088-5 010 $a0-511-04268-X 010 $a0-511-14888-7 010 $a0-511-30608-3 010 $a0-511-54171-6 010 $a0-511-05443-2 035 $a(CKB)1000000000005520 035 $a(EBL)202291 035 $a(OCoLC)559261338 035 $a(SSID)ssj0000209781 035 $a(PQKBManifestationID)11198209 035 $a(PQKBTitleCode)TC0000209781 035 $a(PQKBWorkID)10266831 035 $a(PQKB)11164401 035 $a(UkCbUP)CR9780511541711 035 $a(MiAaPQ)EBC202291 035 $a(Au-PeEL)EBL202291 035 $a(CaPaEBR)ebr10064303 035 $a(CaONFJC)MIL15976 035 $a(PPN)261307029 035 $a(EXLCZ)991000000000005520 100 $a20020528d2003 uy 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aNeuronal substrates of sleep and epilepsy /$fMircea Steriade 205 $a1st ed. 210 $aCambridge ;$aNew York $cCambridge University Press$d2003 215 $a1 online resource (xii, 522 pages) $cdigital, PDF file(s) 300 $aTitle from publisher's bibliographic system (viewed on 05 Oct 2015). 311 $a0-521-81707-2 320 $aIncludes bibliographical references (p. [425]-517) and index. 327 $a1. Pioneering steps in studies on sleep and epilepsy 2. Neuronal types and circuits in sleep and epilepsy 3. Neuronal properties, network operations and behavioral signs during sleep states and wakefulness 4. Plastic changes in thalamocortical systems developing from low-frequency sleep oscillations 5. Neuronal mechanisms of seizures. 330 $aDifferent states of vigilance and various paroxysmal disorders that occur during slow-wave sleep can have the same neural bases. Conventional wisdom holds that sleep is a resting state of the brain, with negligible activity of cortical neurons. Here, the author brings new evidence favoring the idea that during this behavioral state memory traces acquired during waking are consolidated. The author focuses on the coalescence of different sleep rhythms in interacting corticothalamic networks and on three types of paroxysmal disorders, namely spike-wave seizures as in absence epilepsy, Lennox-Gastaut seizures, and temporal-lobe epilepsy. Many physiological correlates of waking and sleep states as well as diverse types of epileptic seizures are also discussed. The book has copious illustrations with examples from in vivo, in vitro and 'in computo' studies, the majority coming from the author's own laboratory. Neuronal Substrates of Sleep and Epilepsy is essential reading for neuroscientists and clinical researchers. 606 $aSleep$xPhysiological aspects 606 $aConvulsions 606 $aNeurons 606 $aNeural circuitry 615 0$aSleep$xPhysiological aspects. 615 0$aConvulsions. 615 0$aNeurons. 615 0$aNeural circuitry. 676 $a612.8/21 700 $aSteriade$b Mircea$01626538 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910826499703321 996 $aNeuronal substrates of sleep and epilepsy$94073544 997 $aUNINA