LEADER 05383nam 2200649 a 450 001 9910825996403321 005 20240313140848.0 010 $a1-118-51741-5 010 $a1-299-18879-6 010 $a1-118-51742-3 010 $a1-118-51743-1 035 $a(CKB)2670000000325827 035 $a(EBL)1120848 035 $a(OCoLC)825404158 035 $a(MiAaPQ)EBC1120848 035 $a(DLC) 2013003472 035 $a(Au-PeEL)EBL1120848 035 $a(CaPaEBR)ebr10657553 035 $a(CaONFJC)MIL450129 035 $a(PPN)184620724 035 $a(EXLCZ)992670000000325827 100 $a20121221d2013 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $2rdacontent 182 $2rdamedia 183 $2rdacarrier 200 00$aMetallofoldamers $esupramolecular architectures from helicates to biomimetics /$fedited by Galia Maayan and Markus Albrecht 205 $a1st ed. 210 $aChichester, West Sussex, U.K. $cJohn Wiley & Sons, Inc.$d2013 215 $a1 online resource (463 p.) 300 $aDescription based upon print version of record. 311 $a0-470-97323-4 320 $aIncludes bibliographical references and index. 327 $aMetallofoldamers: Supramolecular Architectures from Helicates to Biomimetics; Contents; List of Contributors; Foreword; Preface; 1 Metalloproteins and Metallopeptides - Natural Metallofoldamers; 1.1 Introduction; 1.2 Metalloproteins; 1.2.1 Metalloproteins are Nature's "Metallofoldamers!"; 1.2.2 Metal-Triggered Conformational Change of Proteins; 1.2.3 Conformational Change of Metalloproteins Caused by Ligand Binding; 1.2.4 Protein Misfolding: Causes and Implications - Cu, Zn-Superoxide Dismutase; 1.3 Metallopeptides; 1.3.1 Antibiotic Metallopeptides 327 $a1.3.2 Metallopeptides in Neurodegenerative Diseases1.3.3 Other Metallopeptides; 1.4 Conclusion and Perspectives; Acknowledgements; References; 2 Introduction to Unnatural Foldamers; 2.1 General Definition of Foldamers; 2.2 Biotic Foldamers; 2.2.1 Homogeneous Foldamers; 2.2.2 ?-Peptides; 2.2.3 ?-Peptides; 2.2.4 Hybrid Foldamers; 2.2.5 Aliphatic Urea Foldamers; 2.2.6 Foldamers of ?-Aminoxy Acids; 2.2.7 Foldamers Containing Amido Groups; 2.3 Abiotic Foldamers; 2.4 Organization Induced by External Agents; 2.4.1 Organization Induced by Solvents; 2.4.2 Organization Induced by Anions 327 $a2.5 Applications2.6 Conclusions and Outlook; References; 3 Self-Assembly Principles of Helicates; 3.1 Introduction; 3.2 Thermodynamic Considerations in Self-Assembly; 3.2.1 Mononuclear Coordination Complexes; 3.2.2 Extension to Polynuclear Edifices; 3.3 Cooperativity in Self-Assembly; 3.3.1 Allosteric Cooperativity; 3.3.2 Chelate Cooperativity; 3.3.3 Interannular Cooperativity; 3.4 Kinetic Aspects of Multicomponent Organization; 3.5 Understanding Self-Assembly Processes; 3.5.1 Assessment of Cooperativity; 3.5.2 Thermodynamic Modelling; 3.5.3 Solvation Energies and Electrostatic Interactions 327 $a3.6 Secondary Structure and Stabilizing Interactions3.7 Conclusions; References; 4 Structural Aspects of Helicates; 4.1 Introduction; 4.2 Structural Dynamics; 4.3 Template Effects; 4.4 Sequence Selectivity; 4.5 Self-Sorting Effects in Helicate Formation; 4.6 Diastereoselectivity I - "Meso"-Helicate versus Helicate Formation; 4.7 Diastereoselectivity II - Enantiomerically Pure Helicates from Chiral Ligands; 4.7.1 2,2'-Bipyridine Ligands; 4.7.2 2,2':6',2''-Terpyridine and 2,2':6',2'':6'',2-Quaterpyridine Ligands; 4.7.3 2-Pyridylimine Ligands; 4.7.4 Further Hexadentate N-Donor Ligands 327 $a4.7.5 Oxazoline Ligands4.7.6 P-Donor Ligands; 4.7.7 Hydroxamic Acid Ligands; 4.7.8 ?-Diketonate Ligands; 4.7.9 Catecholate Ligands and Other Dianionic Ligand Units; 4.7.10 Non-Covalently Assembled Ligand Strands; 4.8 Summary and Outlook; References; 5 Helical Structures Featuring Thiolato Donors; 5.1 Introduction; 5.2 Coordination Chemistry of Bis- and Tris(Benzene-o-Dithiolato) Ligands; 5.2.1 Mononuclear Chelate Complexes; 5.2.2 Dinuclear Double-Stranded Complexes; 5.2.3 Dinuclear Triple-Stranded Complexes; 5.2.4 Coordination Chemistry of Tripodal Tris(Benzene-o-Dithiolato) Ligands 327 $a5.3 Coordination Chemistry of Mixed Bis(Benzene-o-Dithiol)/Catechol Ligands 330 $aMetallofoldamers are oligomers that fold into three-dimensional structures in a controlled manner upon coordination with metal ions. Molecules in this class have shown an impressive ability to form single-handed helical structures and other three-dimensional architectures. Several metallofoldamers have been applied as sensors due to their selective folding when binding to a specific metal ion, while others show promise for applications as responsive materials on the basis of their ability to fold and unfold upon changes in the oxidation state of the coordinated metal ion, and as novel catal 606 $aMetallofoldamers 606 $aOligomers 606 $aSupramolecular chemistry 615 0$aMetallofoldamers. 615 0$aOligomers. 615 0$aSupramolecular chemistry. 676 $a547/.7 701 $aMaayan$b Galia G$01624731 701 $aAlbrecht$b M$g(Markus)$01624732 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910825996403321 996 $aMetallofoldamers$93959883 997 $aUNINA