LEADER 09883nam 2200673 a 450 001 9910825974003321 005 20240410172550.0 010 $a1-62257-030-8 035 $a(CKB)2550000001043293 035 $a(EBL)3021369 035 $a(SSID)ssj0000876058 035 $a(PQKBManifestationID)12395941 035 $a(PQKBTitleCode)TC0000876058 035 $a(PQKBWorkID)10895470 035 $a(PQKB)10839469 035 $a(MiAaPQ)EBC3021369 035 $a(Au-PeEL)EBL3021369 035 $a(CaPaEBR)ebr10683027 035 $a(OCoLC)923665824 035 $a(EXLCZ)992550000001043293 100 $a20110519d2012 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aSilica nanoparticles$b[electronic resource] $epreparation, properties and uses /$fJuan Vivero-Escoto, editor 205 $a1st ed. 210 $aNew York $cNova Science Publishers$dc2012 215 $a1 online resource (302 p.) 225 1 $aNanaotechnology science and technology 225 1 $aChemical engineering methods and technology 300 $aDescription based upon print version of record. 311 $a1-61324-452-5 320 $aIncludes bibliographical references and index. 327 $aIntro -- SILICA NANOPARTICLES PREPARATION, PROPERTIES AND USES -- SILICA NANOPARTICLES PREPARATION, PROPERTIES AND USES -- Library of Congress Cataloging-in-Publication Data -- CONTENTS -- PREFACE -- Chapter 1 SILICA NANOPARTICLE AS CARRIER FOR BIOSENSING -- ABSTRACT -- 1. INTRODUCTION -- 2. SYNTHESIS OF SILICA-BASED NPS -- 3. DOPED SILICA NPS -- 3.1. Luminophore-Doped Silica NPs -- 3.2. Quantum Dots-Doped Silica NPs -- 3.3. Magnetic Particles-Doped Silica NPs -- 3.4. Noble Metal Particles-Doped Silica NPs -- 3.5. Bifunctional Silica-Based NPs -- 4. CONJUGATION OF SILICA-BASED NPS WITH DESIRED BIOMOLECULES -- 4.1. Physisorption of Biomolecules -- 4.2. Entrapment of Biomolecules by the Sol-Gel Method -- 4.3. Affinity-Based Interactions -- 4.4. Covalent Binding -- 5. SILICA-BASED NPS AS CARRIERS FOR BIOSENSING -- 5.1. Targeting of Cells -- 5.2. Ultrasensitive DNA Detection -- 5.3. Biosenors -- 5.4. Immunoassay -- CONCLUSION -- REFERENCES -- Chapter 2 REACTIVITY OF INORGANIC RADICALS AND EXCITED TRIPLET STATES IN COLLOIDAL SILICA SUSPENSIONS -- ABSTRACT -- 1. INTRODUCTION -- 2. QUENCHING OF BENZOPHENONE TRIPLET STATES BY MODIFIED SILICA NANOPARTICLES -- 2.1. Time- Resolved Phosphorescence Experiments -- 2.2. Laser Flash-Photolysis (LFP) Experiments -- 2.2.1. LFP with BP Solutions -- 2.2.2. LFP with NP1 and NP2 Suspensions in BP Solutions -- 3. REACTION MECHANISMS OF INORGANIC RADICALS AT THE SILICA/WATER INTERFACE -- 3.1. Generation of Grafted Radicals -- 3.2. SO4- -- 3.2.1. NPS Formation and Reactivity -- 3.2.2. SiO Formation and Reactivity -- 3.2. Cl / Cl2- -- 3.3. HPO4- -- 3.4. (SCN)2- -- CONCLUSION -- REFERENCES -- Chapter 3 MULTIFUNCTIONAL MESOPOROUS SILICA NANOPARTICLES FOR CONTROLLED DRUG DELIVERY, MULTIMODAL IMAGING AND SIMULTANEOUS IMAGING AND DRUG DELIVERY -- DEDICATION -- ABSTRACT -- 1. INTRODUCTION. 327 $a2. MSN-BASED CONTROLLED DRUG DELIVERY SYSTEMS -- 2.1. MSN-Based Stimuli-Responsive Drug Delivery Systems -- 2.2. MSN-Based Internal Stimuli-Responsive Drug Delivery Systems -- 2.2.1. pH -- 2.2.2. Redox Potential -- 2.2.3. Biomolecules -- 2.3. External Stimuli-Responsive Drug Release -- 2.3.1 Radiation -- 2.3.2. Oscillating Magnetic Field -- 3. MSN-BASED IMAGING PROBES -- 3.1. MSN-Based Optical Imaging Agents -- 3.2. MSN-Based MR Imaging Agents -- 4. BIOCOMPATIBILITY, PHARMACOKINETICS AND BIODISTRIBUTION OF MESOPOROUS SILICANANOPARTICLES -- 5. IN VIVO SIMULTANEOUS IMAGING AND DRUG DELIVERY -- CONCLUSION -- ACKNOWLEDGMENTS -- REVIEWED BY -- REFERENCES -- Chapter 4 MESOPOROUS SILICA NANOPARTICLES AS A DRUG DELIVERY SYSTEM -- ABSTRACT -- 1. INTRODUCTION -- 2. SILICA PREPARATION METHODS -- 2.1. Conventional Preparation Method -- 2.2. Fluorescent Silica Nanoparticles -- 2.3. Functionalised Silica Nanoparticles -- 3. INFLUENCE OF STRUCTURAL CHARACTERISTICS -- 3.1. Pore Size -- 3.2. Surface Area -- 3.3. Pore Volume -- 4. SILICA NANOPARTICLES AS A DRUG DELIVERY SYSTEM -- 4.1. Controlled Drug Delivery -- 4.2. MSNs in Cancer Treatment -- 4.3. MSNs as Biosensors -- 4.4. Gatekeeping -- 5. BIOCOMPATIBILITY OF SILICA NANOPARTICLES -- 5.2. Cellular Uptake -- 5.3. Cytotoxicity -- REFERENCES -- Chapter 5 SILICA-BASED HYBRID NANOMATERIALS WITH WELL-DEFINED ARCHITECTURES -- ABSTRACT -- 1. INTRODUCTION -- 2. FABRICATION OF SILICA NANOSTRUCTURES -- 2.1. Solid Silica Nanostructures -- 2.2. Hollow Silica Nanostructures -- 2.3. Nanoporous Silica Nanostructures -- 2.4. Other Silica Nanostructures -- 3. SILICA/POLYMER HYBRID NANOSTRUCTURES -- 3.1. Polymer Grafting from Silica Surfaces -- 3.2. Silica Deposited onto Polymer Self-Assembled Architectures -- 4. SILICA/METAL NANOPARTICLES HYBRID NANOSTRUCTURES -- 4.1. Surfaces Immobilized Metal Nanoparticles. 327 $a4.2. Matrix Entrapped Metal Nanoparticles -- 4.2.1. Route I to Silica/Metal Nanostructures -- 4.2.2. Route II to Silica/Metal Nanostructures -- 4.3. Rattle-Like Silica/Metal Nanoparticle Hybrids -- 5. SILICA/CARBON NANOSTRUCTURES -- 5.1. Silica/CNT Hybrid Nanostructures -- 5.1.1. Covalent Processes -- 5.1.2. Non-Covalent Processes -- 5.2. Silica/Graphene Sheets Nanostructures -- 5.3. Other Silica/Carbon Nanomaterials -- 6. SILICA-BASED JANUS NANOSTRUCTURES -- 7. CHALLENGES AND OUTLOOK -- ACKNOWLEDGMENTS -- REFERENCES -- Chapter 6 FUNCTIONAL SILICA NANOPARTICLES SYNTHESIZED BY WATER-IN-OIL MICROEMULSION -- ABSTRACT -- 1. INTRODUCTION -- 1.1. Interest of Functional Nanoparticles and Interest of Silica as Matrix -- 1.2. Possibilities for the Synthesis of Silica Nanoparticles -- 1.3. Synthesis of Silica Nanoparticles by Water-in-Oil Microemulsion -- 1.4. Different Synthesis Strategies -- 1.5. Different Nanoparticle Microstructures -- 1.6. A Wide Range of Already-Published Materials -- 1.7. Complementary of Microemulsions to Other Techniques -- 1.8. Surface Functionalization in Microemulsions -- 1.9. Our Materials and Chapter Topic -- 2. SYNTHESIS OF THE FUNCTIONAL SILICA NANOPARTICLES -- 2.1. Water-in-Oil Microemulsions -- 2.2. Silica Synthesis in Water-in-Oil Microemulsions -- 2.3. Washing and Collection of the Silica Nanoparticles -- 2.4. Experimental Part -- 3. CHARACTERIZATIONS AND POTENTIAL APPLICATIONS OF THE FUNCTIONAL SILICA NANOPARTICLES -- 3.1. SiO2 Nanoparticles for Scratch Resistant Glass -- 3.2. CeO2@SiO2 Anti-UV Nanoparticles -- 3.3. ZnFe2O4@SiO2 and ?-Fe2O3@SiO2 Magnetic Nanoparticles -- 3.4. Cluster@SiO2 Luminescent Nanoparticles -- 3.5. ?-Fe2O3-Cs2[Mo6Br14]@SiO2 Bi-Functional Nanoparticles -- CONCLUSION -- ACKNOWLEDGMENTS -- REFERENCES -- Chapter 7 BIOMEDICAL APPLICATIONS OF NANOSILICA -- ABSTRACT -- INTRODUCTION. 327 $aSILICA NANOPARTICLES -- Preparation and Properties of Silica Nanoparticles -- Modification by Chemical Interaction -- Modification by Physical Interaction -- Applications -- DRUG DELIVERY SYSTEMS -- Polymers Used in Drug Delivery Systems -- Application of Nanosilica in Drug Delivery -- TISSUE ENGINEERING -- Biomaterials and Tissue Engineering -- Polymers Used in Tissue Engineering Scaffolds -- Synthetic Polymers -- Natural Polymers -- Application of Nanosilica in Tissue Engineering -- DENTISTRY -- LIGHT-CURED DENTAL NANOCOMPOSITES -- APPLICATION OF NANOSILICA IN DENTISTRY -- CONCLUSION -- REFERENCES -- Chapter 8 MONODISPERSE LUMINESCENT SILICA NANOPARTICLES: SYNTHESIS, CHARACTERIZATION AND APPLICATION TO THE DNA MICROARRAY TECHNOLOGY -- ABSTRACT -- 1. INTRODUCTION -- 2. SYNTHESIS, FUNCTIONALIZATION AND CHARACTERIZATION OF DYE DOPED SILICA NANOPARTICLES -- 2.1. Synthesis and Functionalization Procedure -- 2.2. Optimization of Dye Loading -- 2.3. Influence of APTES -- 2.4. Influence of NH3 -- 2.5. Diluted Synthesis -- 3. APPLICATION OF DYE DOPED NANOPARTICLES TO DNA MICROARRAY TECHNOLOGY -- 3.1. Bioconjugation of Nanoparticles with Streptavidin -- 3.2. HPV Probe Oligonucleotide Design and Microarray Printing -- 3.3. PCR Amplification of the Sample DNA Strands and Hybridization -- 3.4. Application to the DNA Microarray Technology for HPV Detection -- CONCLUSION -- ACKNOWLEDGMENTS -- REFERENCES -- Chapter 9 DEGREE OF DISPERSION AND COAGULATION OF SILICA NANOPARTICLES DETERMINED BY USING AN ELECTRIC FIELD -- INTRODUCTION -- METHODOLOGY -- RESULTS AND DISCUSSION -- Effect of Supply Voltages -- Mechanism Verification: Configuration of Pearl Chains under an Electric Field -- CONCLUSION -- REFERENCES -- Chapter 10 TEMPERATURE-RESPONSIVE DNA-CAPPED MESOPOROUS SILICA NANOPARTICLES BASED DELIVERY SYSTEM -- DEDICATION -- ABSTRACT -- INTRODUCTION. 327 $aRESULTS AND DISCUSSION -- CONCLUSION -- EXPERIMENTAL SECTION -- Reagents and Materials -- Characterization of Materials -- Synthesis of PAP-MSNs -- Loading of the [Ru(bipy)3]2+ Complex to PAP-MSNs -- Capping of [Ru(bipy)3]2+-Loaded PAP-MSNs with ds-Oligonucleotides -- Release of [Ru(bipy)3]2+ from Oligo-Capped [Ru(bipy)3]2+-Loaded PAP-MSNs -- ACKNOWLEDGMENTS -- REVIEWED BY -- REFERENCES -- INDEX. 410 0$aNanotechnology science and technology series. 410 0$aChemical engineering methods and technology. 606 $aNanosilicon 606 $aNanoparticles 606 $aBiotechnology$xMaterials 606 $aSilica dust$xIndustrial applications 615 0$aNanosilicon. 615 0$aNanoparticles. 615 0$aBiotechnology$xMaterials. 615 0$aSilica dust$xIndustrial applications. 676 $a620.1/93 701 $aVivero-Escoto$b Juan$01637007 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910825974003321 996 $aSilica nanoparticles$93978571 997 $aUNINA