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100   $a19900918d1987      uy         0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 10$aAging in today's environment /$fCommittee on Chemical Toxicity and Aging, Board on Environmental Studies and Toxicology, Commission on Life Sciences, National Research Council
205   $a1st ed.
210   $aWashington, D.C. $cNational Academy Press$d1987
215   $a1 online resource (234 p.)
300   $aCommittee chairmen: Robert N. Butler and Emil A. Pfitzer.
311   $a0-309-06227-6 
320   $aIncludes bibliographical references (p. 171-208).
327   $aAGING In Today's Environment; Copyright; Preface; Contents; Executive Summary; AGING AND NUTRITION; AGING AND SUSCEPTIBILITY TO DISEASE; AGING, DISEASE, PHARMACEUTICAL USE, AND CHEMICAL RESPONSE; AGING AND ENVIRONMENTAL FACTORS; MODEL SYSTEMS FOR RESEARCH; CONCLUSIONS; 1 Aging and Environmental Exposure ; BASIS OF THE SCIENTIFIC PROBLEM; STRUCTURE OF THE REPORT; 2 The Aging Population and the Psychosocial Implications of Aging ; DEMOGRAPHIC CONSIDERATIONS OF AN AGING POPULATION; PSYCHOSOCIAL ENVIRONMENT; 3 Principles of Gerontology ; CONCEPTUAL CONTEXT OF GERONTOLOGY; THEORIES OF AGING
327   $aDeterministic TheoriesDevelopmental Switches in Gene Expression; Neuroendocrine-Cascade Theories; Stochastic Theories; Intrinsic Mutagenesis Theory; Protein-Synthesis Error Catastrophe; Free Radicals; Posttranslational Glycation of Proteins and DNA; Thymic Involution as a Pacemaker of Immunosenescence; BIOMARKERS OF AGE OR AGING; ALTERED SUSCEPTIBILITY OF THE AGED; 4 Principles of Toxicology in the Context of Aging ; CHEMICAL FATE AND EFFECT; Absorption; Distribution; Metabolism and Elimination; MECHANISMS OF TOXICITY AT THE MOLECULAR, CELLULAR, AND TISSUE LEVEL; Molecular Action
327   $aCellular EffectsEffects at the Tissue Level; PHARMACOGENETICS; BIOLOGIC MARKERS; TOXICITY TESTING; 5 Characteristics of the Environment, Aging, and the Aged ; NUTRITION; Effects of Nutrition on Toxicity; Nutrition and Cancer; Nutrition and Aging; Background and Criteria for Evaluating Aging; Food Restriction; Dietary Protein Intake; Dietary Fat Intake; Dietary Carbohydrate Intake; Dietary Vitamin Intake; Dietary Mineral Intake; Special Dietary Requirements of the Aged; PHARMACEUTICALS; Demographic Considerations; Patterns of Drug Use and Drug Prescribing; Ambulatory Populations
327   $aHospital PopulationsLong-Term-Care Facilities; Medication Compliance in the Elderly; Adverse Drug Reactions; LIFE-STYLE; Deliberate Chemical Exposure; Learned Helplessness; Atrophy of Disuse; Indoor Pollutants; Temperature; Radon; Formaldehyde; Combustion Products; Asbestos; Environmental Tobacco Smoke; Pesticides; 6 Environmental Effects on Age-Associated Diseases and Changes in Organ Function ; DEMOGRAPHICS OF AGE-ASSOCIATED DISEASES; SKIN; VISION; Cataracts; Glaucoma; Diabetic Retinopathy; Aging-Related Macular Degeneration; HEARING; NERVOUS SYSTEM; Changes Associated with Aging
327   $aInduced Disorders and DiseasesNeurotoxicants; RESPIRATORY SYSTEM; CARDIOVASCULAR SYSTEM; RENAL SYSTEM; IMMUNE SYSTEM; SEXUALITY; ROLE OF ENVIRONMENT IN BONE METABOLISM AND VITAMIN D NUTRITION; 7 Model Systems for the Evaluation of Toxic Agents Affecting Aging or Age-Related Diseases ; CONSIDERATIONS IN CHOOSING AND DESIGNING MODEL SYSTEMS; EXAMPLES OF MODEL SYSTEMS; In Vitro Models; Nonmammalian Animal [Models; Mammalian Models; Epidemiologic Models; LIFE-SPAN MODULATION BY DRUG TREATMENT; 8 Conclusions ; 9 Recommendations ; RESEARCH; EDUCATION; FUNDING AND RESOURCES; References
327   $aAppendix Resources for Studying Aging
606   $aOlder people$xEffect of environment on
606   $aAging
606   $aEnvironmental health
606   $aHuman beings$xEffect of environment on
615  0$aOlder people$xEffect of environment on.
615  0$aAging.
615  0$aEnvironmental health.
615  0$aHuman beings$xEffect of environment on.
676   $a612.67
701   $aButler$b Robert N.$f1927-2010.$01713202
701   $aPfitzer$b Emil A$01713203
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910825510403321
996   $aAging in today's environment$94105998
997   $aUNINA