LEADER 06276nam 2200637Ia 450 001 9910825483203321 005 20240514073806.0 010 $a1-280-59259-1 010 $a9786613622426 010 $a1-118-18072-0 010 $a1-118-18073-9 010 $a1-118-18070-4 035 $a(CKB)2670000000177366 035 $a(EBL)822073 035 $a(OCoLC)787842595 035 $a(SSID)ssj0000638332 035 $a(PQKBManifestationID)11354306 035 $a(PQKBTitleCode)TC0000638332 035 $a(PQKBWorkID)10707900 035 $a(PQKB)10218820 035 $a(MiAaPQ)EBC822073 035 $a(Au-PeEL)EBL822073 035 $a(CaPaEBR)ebr10560591 035 $a(CaONFJC)MIL362242 035 $a(PPN)176948724 035 $a(EXLCZ)992670000000177366 100 $a20110817d2012 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aMass spectrometry handbook /$fedited by Mike S. Lee 205 $a1st ed. 210 $aHoboken, NJ $cJ. Wiley & Sons$dc2012 215 $a1 online resource (1340 p.) 225 1 $aWiley series on pharmaceutical science and biotechnology: practices, applications and methods 300 $aIncludes index. 311 $a0-470-53673-X 327 $aIntro -- MASS SPECTROMETRY HANDBOOK -- CONTENTS -- FOREWORD -- PREFACE -- CONTRIBUTORS -- SECTION I: BIOTECHNOLOGY/PROTEINS -- 1: TARGETED PROTEOMICS USING IMMUNOAFFINITY PURIFICATION -- 2: MASS SPECTROMETRY-BASED METHODS TO INVESTIGATE POSTTRANSLATIONAL PROTEIN MODIFICATIONS BY LIPID PEROXIDATION PRODUCTS -- 3: IMAGING MASS SPECTROMETRY (IMS) FOR BIOLOGICAL APPLICATION -- 4: METHODOLOGIES FOR IDENTIFYING MICROORGANISMS AND VIRUSES BY MASS CATALOGING OF RNAs -- SECTION II: PHARMACEUTICAL -- 5: PRECLINICAL PHARMACOKINETICS: INDUSTRIAL PERSPECTIVE -- 6: LC-MS IN DRUG METABOLISM AND PHARMACOKINETICS: A PHARMACEUTICAL INDUSTRY PERSPECTIVE -- 7: QUANTITATIVE MASS SPECTROMETRY IN SUPPORT OF PHARMACOKINETIC STUDIES -- 8: DETERMINATION OF PHARMACOKINETIC PARAMETERS BY HPLC-MS/MS AND UPLC-MS/MS -- 9: METHODS FOR SCREENING ENANTIOSELECTIVE INTERACTIONS IN THE SOLUTION PHASE USING ESI-MS -- 10: HYDROGEN/DEUTERIUM EXCHANGE MASS SPECTROMETRY (HDX MS) IN THE STUDIES OF ARCHITECTURE, DYNAMICS, AND INTERACTIONS OF BIOPHARMACEUTICAL PRODUCTS -- 11: TOF-SIMS APPLICATIONS TO BIOIMAGING AND BIOMOLECULE EVALUATION METHODS -- 12: ACCELERATOR MASS SPECTROMETRY IN PHARMACEUTICAL DEVELOPMENT -- SECTION III: CLINICAL ANALYSIS -- 13: MASS SPECTROMETRY IN CLINICAL ANALYSIS: SCREENING FOR INBORN ERRORS IN METABOLISM -- 14: MASS SPECTROMETRY FOR STEROID ANALYSIS -- SECTION IV: FORENSICS -- 15: FORENSIC APPLICATIONS OF ISOTOPE RATIO MASS SPECTROMETRY -- 16: ANALYSIS OF TRIACETONE TRIPEROXIDE EXPLOSIVE BY MASS SPECTROMETRY -- SECTION V: SPACE EXPLORATION -- 17: MASS SPECTROMETRY IN SOLAR SYSTEM EXPLORATION -- 18: APPLICATION OF GC × GC-TOFMS TO THE CHARACTERIZATION OF EXTRATERRESTRIAL ORGANIC MATTER -- SECTION VI: HOMELAND SECURITY -- 19: METHODS OF MASS SPECTROMETRY IN HOMELAND SECURITY APPLICATIONS -- 20: HOMELAND SECURITY -- 21: MASS SPECTROMETRY IN HOMELAND SECURITY. 327 $a22: MEASUREMENTS OF SURFACE CONTAMINANTS AND SORBED ORGANICS USING AN ION TRAP SECONDARY ION MASS SPECTROMETER -- 23: DETERMINATION OF ACTINIDES: DETERMINATION OF LOW-CONCENTRATION URINE URANIUM 235/238 ISOTOPE RATIOS -- SECTION VII: FOOD ANALYSIS -- 24: MASS SPECTROMETRY IN AGRICULTURE, FOOD, AND FLAVORS: SELECTED APPLICATIONS -- 25: TOP-DOWN PROTEOMIC IDENTIFICATION OF PROTEIN BIOMARKERS OF FOOD-BORNE PATHOGENS USING MALDI-TOF-TOF-MS/MS -- SECTION VIII: ENVIRONMENTAL -- 26: DETERMINATION OF DITHIOCARBAMATE FUNGICIDES IN FOOD BY HYDROPHILIC INTERACTION LIQUID CHROMATOGRAPHY/MASS SPECTROMETRY -- 27: DISINFECTANT AND BY-PRODUCT ANALYSIS IN WATER TREATMENT BY MEMBRANE INTRODUCTION MASS SPECTROMETRY -- 28: PROTON TRANSFER REACTION MASS SPECTROMETRY (PTR-MS) -- 29: DETERMINATION OF CHLORINATED COMPOUNDS IN DIALYSIS WATER AND IN BIOLOGICAL FLUIDS/MATRICES -- SECTION IX: GEOLOGICAL -- 30: MASS SPECTROMETRY TECHNIQUES FOR ANALYSIS OF OIL AND GAS TRAPPED IN FLUID INCLUSIONS -- 31: LA-MC-ICP-MS APPLIED TO U-PB ZIRCON GEOCHRONOLOGY -- 32: HYDROCARBON PROCESSING -- 33: HYDROCARBON PROCESSING: MALDI-MS OF POLYDISPERSE HYDROCARBON SAMPLES -- 34: RENEWABLE ENERGY: MASS SPECTROMETRY IN BIOFUEL RESEARCH -- SECTION X: ARCHAEOLOGY -- 35: MASS SPECTROMETRY IN ARCHAEOLOGY -- 36: ARCHAEOMETRIC DATA FROM MASS SPECTROMETRIC ANALYSIS OF ORGANIC MATERIALS: PROTEINS, LIPIDS, TERPENOID RESINS, LIGNOCELLULOSIC POLYMERS, AND DYESTUFF -- 37: LASER ABLATION ICP-MS IN ARCHAEOLOGY -- 38: SPATIALLY RESOLVED MS IN THE STUDY OF ART AND ARCHAEOLOGICAL OBJECTS -- 39: LASER ABLATION-INDUCTIVELY COUPLED PLASMA MASS SPECTROMETRY FOR THE INVESTIGATION OF ARCHAEOLOGICAL SAMPLES -- SECTION XI: SURFACE ANALYSIS -- 40: MASS SPECTROMETRY IN SEMICONDUCTOR RESEARCH -- 41: ANALYSIS OF THIN AND THICK FILMS -- 42: SIMS FOR ORGANIC FILM ANALYSIS. 327 $a43: CERAMICS: CONTRIBUTION OF SECONDARY ION MASS SPECTROMETRY (SIMS) TO THE STUDY OF CRYSTAL CHEMISTRY OF MICA MINERALS -- SECTION XII: POLYMERS -- 44: ETV-ICPMS FOR ANALYSIS OF POLYMERS -- 45: POLYMERS -- 46: MASS SPECTROSCOPY IN POLYMER RESEARCH -- 47: LASER MASS SPECTROMETRY APPLIED TO THE ANALYSIS OF POLYMERS -- SECTION XIII: ANALYTICAL TECHNIQUES -- 48: MEASURING THERMODYNAMIC PROPERTIES OF METALS AND ALLOYS -- 49: HIGH-PERFORMANCE THIN-LAYER CHROMATOGRAPHY-MASS SPECTROMETRY FOR ANALYSIS OF SMALL MOLECULES -- 50: LASER IONIZATION MASS SPECTROMETRY OF INORGANIC IONS -- 51: MASS SPECTROMETRY IN THE SSITKA STUDIES -- 52: PROTON TRANSFER REACTION MASS SPECTROMETRY: APPLICATIONS IN THE LIFE SCIENCES -- INDEX. 410 0$aWiley series on pharmaceutical science and biotechnology: practices, applications and methods. 606 $aMass spectrometry$vHandbooks, manuals, etc 606 $aSpectrum analysis 615 0$aMass spectrometry 615 0$aSpectrum analysis. 676 $a543/.65 701 $aLee$b Mike S.$f1960-$01593247 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 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