LEADER 03269nam 2200661 450 001 9910825339503321 005 20230803220647.0 010 $a0-19-756286-8 010 $a0-19-933716-0 010 $a0-19-933715-2 035 $a(CKB)2550000001181270 035 $a(EBL)1602520 035 $a(SSID)ssj0001080520 035 $a(PQKBManifestationID)12462479 035 $a(PQKBTitleCode)TC0001080520 035 $a(PQKBWorkID)11071191 035 $a(PQKB)10993607 035 $a(MiAaPQ)EBC1602520 035 $a(StDuBDS)EDZ0002341517 035 $a(Au-PeEL)EBL1602520 035 $a(CaPaEBR)ebr10826259 035 $a(CaONFJC)MIL561296 035 $a(OCoLC)868264144 035 $a(EXLCZ)992550000001181270 100 $a20140124h20142014 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aHallelujah moments $etales of drug discovery /$fEugene H. Cordes 210 1$aNew York, New York :$cOxford University Press,$d2014. 210 4$dİ2014 215 $a1 online resource (258 p.) 225 1 $aOxford scholarship online 300 $aIncludes index. 311 $a0-19-933714-4 311 $a1-306-30045-2 320 $aIncludes bibliographical references and index. 327 $aCover; Contents; Preface; Acknowledgments; 1. Seduced by Drug Discovery; 2. The Small Molecules of Life; 3. Proteins: Molecular Wonders in Three Dimensions; 4. Proteins Perform Multiple Functions: Enzymes, Receptors, Ion Channel Proteins; 5. Drug Discovery and Development: The Road from an Idea to Promoting Human Health; 6. Finasteride: The Gary and Jerry Show; 7. Basic Research, Snake Venoms, and ACE Inhibitors: Ondetti, Cushman, and Patchett; 8. Statins: Protection Against Heart Attacks and Strokes-Hallelujah!; 9. Th e Perils of Primaxin; 10. Avermectins: Molecules of Life Battle Parasites 327 $a11. Fludalanine: Nice Try But No Hallelujah12. Diabetes Breakthroughs: Januvia and Janumet; NOTES; INDEX; A; B; C; D; E; F; G; H; I; J; K; L; M; N; O; P; Q; R; S; T; U; V; W; X; Y; Z 330 8 $aPharmeceutical drug discovery has wide-reaching and obvious effects on the lives of people everywhere, and yet the general public knows very little about the way in which these important products are conceived. We rely on pharmaceuticals to keep us healthy in countless ways, with almost no understanding of the process behind the creation of the drugs we use. In this book, Eugene Cordes reveals just how some of the most important and influential drugs are made. He shares his firsthand knowledge of the drug-discovery world, having spent a long and distinguished career on both the academic and industrial side of pharmaceutical research. 410 0$aOxford scholarship online. 606 $aDrug development$xHistory 606 $aDrugs$xResearch 606 $aPharmaceutical chemistry 615 0$aDrug development$xHistory. 615 0$aDrugs$xResearch. 615 0$aPharmaceutical chemistry. 676 $a615.19 700 $aCordes$b Eugene H$0296633 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910825339503321 996 $aHallelujah moments$94125476 997 $aUNINA