LEADER 03762nam 2200709Ia 450 001 9910823645003321 005 20200520144314.0 010 $a1-107-16320-X 010 $a1-280-54139-3 010 $a9786610541393 010 $a0-511-22556-3 010 $a0-511-22613-6 010 $a0-511-22424-9 010 $a0-511-31774-3 010 $a0-511-48913-7 010 $a0-511-22491-5 035 $a(CKB)1000000000352813 035 $a(EBL)268222 035 $a(OCoLC)560236069 035 $a(SSID)ssj0000224080 035 $a(PQKBManifestationID)11200774 035 $a(PQKBTitleCode)TC0000224080 035 $a(PQKBWorkID)10205532 035 $a(PQKB)11130588 035 $a(UkCbUP)CR9780511489136 035 $a(MiAaPQ)EBC268222 035 $a(Au-PeEL)EBL268222 035 $a(CaPaEBR)ebr10131641 035 $a(CaONFJC)MIL54139 035 $a(PPN)183064976 035 $a(EXLCZ)991000000000352813 100 $a20040319d2004 uy 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 14$aThe politics of personalised medicine $epharmacogenetics in the clinic /$fAdam Hedgecoe 205 $a1st ed. 210 $aCambridge, UK ;$aNew York $cCambridge University Press$d2004 215 $a1 online resource (vii, 208 pages) $cdigital, PDF file(s) 225 1 $aCambridge studies in society and the life sciences 300 $aTitle from publisher's bibliographic system (viewed on 05 Oct 2015). 311 $a0-521-60265-3 311 $a0-521-84177-1 320 $aIncludes bibliographical references (p. 182-204) and index. 327 $aPersonalised medicine : a revolution in healthcare -- Pharacogenetics, expectation and promissory science -- Genetics, moral risk and professional resistance -- Clinical resistance to Alzheimer's pharmacogenetics -- Research, industry and pharamacogenetic literacy -- Engineering the clinic : getting personalised medicine into practice -- The fourth hurdle : cost-effectiveness and the funding of pharmacogenetics -- Disappointment and disclosure in the pharmacogenetic clinic -- The personalised is political. 330 $aPharmacogenetics, the use of genetic testing to prescribe and develop drugs, has been hailed as a revolutionary development for the pharmaceutical industry and modern medicine. Supporters of 'personalised medicine' claim the result will be safer, cheaper, more effective drugs, and their arguments are beginning to influence policy debates. Based on interviews with clinicians, researchers, regulators and company representatives, this book explores the impact of pharmacogenetics on clinical practice, following two cases of personalised medicine as they make their way from the laboratory to the clinic. It highlights the significant differences between the views of supporters of pharmacogenetics in industry and those who use the technology at the clinical 'coal face'. Theoretically, this work builds on the developing area of the sociology of socio-technical expectations, highlighting the way in which promoters of new technologies build expectations around it, through citation and the creation of technological visions. 410 0$aCambridge studies in society and the life sciences. 606 $aPharmacogenetics$xSocial aspects 606 $aPharmacology$xSocial aspects 615 0$aPharmacogenetics$xSocial aspects. 615 0$aPharmacology$xSocial aspects. 676 $a615.5/8 700 $aHedgecoe$b Adam$01641940 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910823645003321 996 $aThe politics of personalised medicine$93986367 997 $aUNINA