LEADER 06270nam 2200601Ia 450 001 9910823537503321 005 20200520144314.0 010 $a1-61122-229-X 035 $a(CKB)2550000001041577 035 $a(EBL)3018603 035 $a(SSID)ssj0000852956 035 $a(PQKBManifestationID)12308008 035 $a(PQKBTitleCode)TC0000852956 035 $a(PQKBWorkID)10854206 035 $a(PQKB)11334143 035 $a(MiAaPQ)EBC3018603 035 $a(Au-PeEL)EBL3018603 035 $a(CaPaEBR)ebr10661541 035 $a(OCoLC)831625640 035 $a(EXLCZ)992550000001041577 100 $a20100824d2011 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aOrganic solvents $eproperties, toxicity, and industrial effects /$fRyan E. Carter, editor 205 $a1st ed. 210 $aNew York $cNova Science Publishers$dc2011 215 $a1 online resource (185 p.) 225 1 $aChemical engineering methods and technology 225 1 $aBiotechnology in agriculture, industry and medicine 300 $aDescription based upon print version of record. 311 $a1-61761-881-0 320 $aIncludes bibliographical references and index. 327 $aIntro -- ORGANIC SOLVENTS: PROPERTIES, TOXICITY, AND INDUSTRIAL EFFECTS -- ORGANIC SOLVENTS: PROPERTIES, TOXICITY, AND INDUSTRIAL EFFECTS -- CONTENTS -- PREFACE -- Chapter 1 CO-SOLVENT APPLICATION FOR BIOLOGICAL SYSTEMS -- ABSTRACT -- 1. INTRODUCTION -- 2. SOLVENT EFFECT OVERVIEW -- APPLICATIONS OF CO-SOLVENTS -- 1. Enhancing Protein Stability -- B. Protein Biopharmaceuticals -- C. Chromatography -- D. Sub-Zero Temperature Enzymology -- E. Application of the Organic Solvent for NMR Studies -- F. Powder Enzyme Reaction in Organic Solvent: Low Water Activity -- G. Protein Precipitation -- H. Virus Inactivation and Processing -- Virus Inactivation -- Virus and Plasmid Processing/Purification -- CONCLUSION -- REFERENCES -- Chapter 2 LIPASE-CATALYZED SYNTHESIS OF EDIBLE SURFACTANTS IN MICROAQUEOUS ORGANIC SOLVENTS -- ABSTRACT -- INTRODUCTION -- 1. EQUILIBRIUM CONSTANT FOR LIPASE-CATALYZED CONDENSATION OF SACCHARIDE AND LAURIC ACID IN WATER-MISCIBLE ORGANIC SOLVENTS IN A BATCH REACTION -- 2. CONTINUOUS PRODUCTION OF ACYL ,MANNOSES BY IMMOBILIZED LIPASE USING A PACKED-BED REACTOR AND THEIR SURFACTANT PROPERTIES -- 3. SYNTHESES OF LAUROYL PHENOLIC GLYCOSIDES BY IMMOBILIZED LIPASE IN ORGANIC SOLVENT AND THEIR ANTIOXIDATIVE ACTIVITIES -- CONCLUSION -- ACKNOWLEDGMENTS -- REFERENCES -- Chapter 3 ANALYSIS OF THE ORGANIC SOLVENT EFFECT ON THE STRUCTURE OF DEHYDRATED PROTEINS BY ISOTHERMAL CALORIMETRY, DIFFERENTIAL SCANNING CALORIMETRY AND FTIR SPECTROSCOPY -- ABSTRACT -- 1. BACKGROUND AND SIGNIFICANCE -- 2. METHODOLOGY -- 2.1. FTIR Spectroscopy -- 2.2. Isothermal Calorimetry -- 2.3. Differential Scanning Calorimetry -- 2.4. Solubility Control -- 2.5. Water Content of Organic Solvents -- 3. DRIED PROTEINS IN ANHYDROUS ORGANIC SOLVENTS -- 3.1. Choice of Proteins -- 3.2. Choice of Organic Solvents -- 3.3. Solvent Hydrophilicity. 327 $a3.4. Definition of the System under Study -- 3.5. Analysis and Band Assignment of Protein Infrared Spectra -- 3.6. Interaction Enthalpies of the Dried Proteins with Organic Solvents -- 3.7. Effect of Solvent Hydrophilicity on the Enthalpy and Integral Absorbance Changes -- 3.8. The Dried Proteins in Anhydrous Organic Solvents as Studied by Differential Scanning Calorimetry -- 3.9. Effect of Hydrogen Bond Accepting Ability -- 3.10. Effect of Hydrogen Bond Donating Ability -- 3.11. Effect of Organic Solvents on the Structure of the Dehydrated Proteins -- ACKNOWLEDGMENTS -- REFERENCES -- Chapter 4 ORGANIC-SOLVENT TOLERANT GRAM-POSITIVE BACTERIA: APPLICATIONS AND MECHANISMS OF TOLERANCE -- ABSTRACT -- 1. INTRODUCTION -- 2. PREDICTING SOLVENT TOXICITY -- 3. ORGANIC-SOLVENT TOLERANCE IN GRAM POSITIVE BACTERIA -- 3.1. Environmental Niches for Isolation of Tolerant Bacteria -- 3.2. Bacterial Mechanisms of Tolerance and Adaptation to Organic Solvents -- 3.2.1. Biodegradation of Toxic Compounds -- 3.2.2. Adaptation by Cell Wall and Membrane Modifications -- 3.2.2.1. Fatty Acid Composition -- 3.2.2.2. Mycolic Acid Composition -- 3.2.3. Efflux Pumps and other Mechanisms -- CONCLUSIONS -- ACKNOWLEDGMENTS -- REFERENCES -- Chapter 5 TOXICITY OF ORGANIC SOLVENTS AND IONIC LIQUIDS TO LACTIC ACID-PRODUCING MICROBES -- ABSTRACT -- INTRODUCTION -- 1. TOXICITY OF ORGANIC SOLVENTS TO LACTIC ACID-PRODUCING MICROBES -- 2. TOXICITY OF IMIDAZOLIUM-BASED IONIC LIQUIDS ON LACTIC ACID-PRODUCING BACTERIA -- 3. GREENNESS OF IONIC LIQUIDS AS AN ALTERNATIVE SOLVENT -- CONCLUSION -- REFERENCES -- Chapter 6 EFFECT OF HYDROGEN BOND ACCEPTING ORGANIC SOLVENTS ON THE BINDING OF COMPETITIVE INHIBITOR AND STORAGE STABILITY OF -CHYMOTRYPSIN1 -- ABSTRACT -- 1. BACKGROUND AND SIGNIFICANCE. 327 $a2. BINDING OF THE COMPETITIVE INHIBITOR PROFLAVIN AND THE STORAGE STABILITY OF -CHYMOTRYPSIN IN ORGANIC SOLVENTS -- 2.1. Choice of Organic Solvents -- 2.2. Thermodynamic Activity of Water in Organic Solvents -- 2.3. Binding of Proflavin in Water -- 2.4. Spectra of Proflavin in Water-Organic Mixtures -- 2.5. Binding of Proflavin in Organic Solvents -- 2.6. Enzyme Storage Stability -- 2.7. The State of Hydrogen Bond Network of Water in Hydrogen Bond Accepting Organic Solvents as Studied By FTIR Spectroscopy -- 2.8. Excess Partial Molar Quantities of Water and Organic Solvents -- 2.9. Effect of Organic Solvents on Storage Stability and Binding of Competitive Inhibitor -- REFERENCES -- Chapter 7 REGULARITIES OF ORGANIC SOLVENTS PENETRATION INTO TETRAFLUOROETHYLENE-PROPYLENE COPOLYMER1 -- ABSTRACT -- REFERENCES -- INDEX. 410 0$aChemical engineering methods and technology. 410 0$aBiotechnology in agriculture, industry and medicine series. 606 $aOrganic solvents 606 $aOrganic compounds 615 0$aOrganic solvents. 615 0$aOrganic compounds. 676 $a660/.29482 701 $aCarter$b Ryan E$01599615 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910823537503321 996 $aOrganic solvents$93922371 997 $aUNINA