LEADER 03443nam 2200601 a 450 001 9910823534303321 005 20240516061110.0 010 $a1-283-23971-X 010 $a9786613239716 010 $a1-118-02314-5 010 $a1-118-02315-3 010 $a1-118-02313-7 035 $a(CKB)2550000000046087 035 $a(EBL)693199 035 $a(OCoLC)761318487 035 $a(SSID)ssj0000608001 035 $a(PQKBManifestationID)12181343 035 $a(PQKBTitleCode)TC0000608001 035 $a(PQKBWorkID)10591922 035 $a(PQKB)10010094 035 $a(MiAaPQ)EBC693199 035 $a(Au-PeEL)EBL693199 035 $a(CaPaEBR)ebr10494666 035 $a(CaONFJC)MIL323971 035 $a(PPN)240481712 035 $a(EXLCZ)992550000000046087 100 $a20101105d2011 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aDrug discrimination $eapplications to medicinal chemistry and drug studies /$fedited by Richard A. Glennon, Richard Young 205 $a1st ed. 210 $aHoboken, N.J. $cWiley$d2011 215 $a1 online resource (533 p.) 300 $aDescription based upon print version of record. 311 $a0-470-43352-3 320 $aIncludes bibliographical references and index. 327 $aAn introduction to drug discrimination -- Methodological considerations -- Drug discrimination : practical considerations? -- Role of stereochemistry in drug discrimination studies -- Drug discrimination and in vivo structure-activity relationships -- Drug discrimination and mechanisms of drug action -- Drug discrimination and development of novel agents and pharmacological tools -- Perceptual drug discriminative aspects of the endocannabinoid signaling system in animals and man -- Discriminative stimulus properties of receptor antagonists -- The discrimination of drug mixtures -- Making the right choice : lessons from drug discrimination for research on drug reinforcement and drug self-administration -- Inhalant drug discrimination: methodology, literature review, and future directions -- Drug discrimination studies in rhesus monkeys : drug dependence and withdrawal -- Human drug discrimination : methodological considerations and application to elucidating the neuropharmacology of amphetamines -- Nicotine discrimination in humans -- Drug discrimination : a perspective. 330 $aDrug discrimination: a practical guide to its contributions to the invention of new chemical entities and evaluations of new or known pharmacological agents Drug discrimination can be described as a ""drug detection"" procedure that uses a pharmacologically active agent as the subjective stimulus. Although the procedure does require some effort to implement, it can be an extremely important tool for understanding drug action. Whereas medicinal chemists should come to learn the types of information that drug discrimination studies can offer, pharmacologists and psychologists might come to 606 $aDrug discrimination (Pharmacology) 615 0$aDrug discrimination (Pharmacology) 676 $a615/.19 701 $aGlennon$b Richard A.$f1945-$092557 701 $aYoung$b Richard$f1952 October 24-$01748643 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910823534303321 996 $aDrug discrimination$94181591 997 $aUNINA