LEADER 02922oam 2200529I 450 001 9910823477203321 005 20230807204148.0 010 $a0-429-17139-0 010 $a1-4822-0724-9 024 7 $a10.1201/b18060 035 $a(CKB)2670000000557263 035 $a(EBL)1441443 035 $a(SSID)ssj0001421379 035 $a(PQKBManifestationID)11770444 035 $a(PQKBTitleCode)TC0001421379 035 $a(PQKBWorkID)11424091 035 $a(PQKB)11014997 035 $a(MiAaPQ)EBC1441443 035 $a(OCoLC)903675836 035 $a(EXLCZ)992670000000557263 100 $a20180331h20152015 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aMechanobiology of the endothelium /$feditor, Helim Aranda-Espinoza, Fischell Department of Bioengineering, University of Maryland College Park, MD USA 210 1$aBoca Raton :$cCRC Press,$d[2015] 210 4$dİ2015 215 $a1 online resource (278 p.) 300 $aA Science Publishers Book. 311 $a1-322-97599-X 311 $a1-4822-0725-7 327 $aCover; Preface; Contents; Chapter 1: The Endothelium as a Mechanosensor; Chapter 2: Mechanobiology of the Endothelial Nucleus; Chapter 3: Cancer Metastasis and Biomechanics of the Endothelium; Chapter 4: Valvular Endothelial Mechanobiology; Chapter 5: Environmental Factors that Influence the Response of the Endothelium to Flow; Chapter 6: Differential Response of the Endothelium to Simultaneous Chemical and Mechanical Stimulation in Inflammation Response; Chapter 7: The Role of Cholesterol and Lipoproteins in Control of Endothelial Biomechanics 327 $aChapter 8: Implications of Fluid Shear Stress in Capillary Sprouting during Adult Microvascular Network RemodelingChapter 9: Endothelial Cell Adhesion Molecules and Drug Delivery Applications; Chapter 10: Leukocyte Transendothelial Migration: A Biophysical Event; Color Plate Section 330 $a

The endothelium is an excellent example of where biology meets physics and engineering. It must convert mechanical forces into chemical signals to maintain homeostasis. It also controls the immune response, drug delivery through the vasculature, and cancer metastasis. Basic understanding of these processes is starting to emerge and the knowledge gained from research is now being used in applications from drug delivery to imaging modalities. This book reviews current knowledge in mechanobiology of the endothelium and its implications for the development of theranostic devices.

606 $aEndothelium$xPhysiology 615 0$aEndothelium$xPhysiology. 676 $a611.0187 676 $a611/.0187 702 $aAranda-Espinoza$b Helim 801 0$bFlBoTFG 801 1$bFlBoTFG 906 $aBOOK 912 $a9910823477203321 996 $aMechanobiology of the endothelium$93941359 997 $aUNINA