LEADER 03548nam 2200541Ia 450 001 9910823409503321 005 20200520144314.0 010 $a1-60876-720-5 035 $a(CKB)2550000001041403 035 $a(EBL)3018589 035 $a(SSID)ssj0000836221 035 $a(PQKBManifestationID)11461968 035 $a(PQKBTitleCode)TC0000836221 035 $a(PQKBWorkID)11007781 035 $a(PQKB)10628907 035 $a(MiAaPQ)EBC3018589 035 $a(Au-PeEL)EBL3018589 035 $a(CaPaEBR)ebr10660450 035 $a(OCoLC)923659016 035 $a(EXLCZ)992550000001041403 100 $a20090213d2009 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aTelomeres $efunction, shortening and lengthening /$fLeonardo Mancini, editor 205 $a1st ed. 210 $aNew York $cNova Biomedical Books$dc2009 215 $a1 online resource (498 p.) 300 $aDescription based upon print version of record. 311 $a1-60692-350-1 320 $aIncludes bibliographical references and index. 327 $aTelomere dynamics and biology in human progeroid syndromes / Terence Davis, Hannah S.E. Tivey, and David Kipling -- The role of telomere-telomerase system in age-related fitness decline : a tameable process / Giacinto Libertini -- Cytogenetic evaluation of telomere dysfunction : chromosomal aberrations involving telomeres and interstitial telomeric sequences / Alejandro D. Bolza?n -- Telomeres-telomerase biology and their role in renal and other chronic diseases / Kordinas Vasileios ... [et al.] -- Telomerase and telomere dynamics in cancer : clinical application for cancer diagnosis / Eiso Hiyama, Keiko Hiyama -- Telomeres and chromosome segregation / Antonella Sgura and Daniela Cimini -- Telomere-based genome-protective responses : a mammalian improvement on the bacterial SOS response? / Barbara A. Gilchrest, Mark S. Eller -- Telomere lengthening from oocyte to embryonic stem cell / Eva Pericuesta ... [et al.] -- Transcriptional activity at the telomeres of chironomus (diptera) : its possible role in the lengthening of the telomeres / J.L. Diez ... [et al.] -- 327 $aTelomerase activity : application to diagnosis of human carcinoma / Liliana N. Guerra -- Telomere shortening in diabetes mellitus / Nicholas Tentolouris, Athanasia Papazafiropoulou -- Do alterations in the three-dimensional organization of telomeres indicate malignant transformation? / Sandrine Lacoste, Hans Knecht, and Sabine Mai -- Telomeres : function, shortening and lengthening / Barry Flanary -- Telomerase regulation in stem cells : how to flip the switch? / Rich Allsopp -- Telomere maintenance mechanisms in bone and soft tissue tumors / Toshihiro Matsuo ... [et al.] -- Genetic polymorphisms of human telomerase reverse transcriptase (hTERT) : mini review / Yumiko Matsubara, Mitsuru Murata, and Yasuo Ikeda -- Genetic inhibition of telomere lengthening in cancer prevention and treatment / F. Mathias Bollmann -- Telomeres : function, shortening, and lengthening / Barry Flanary -- Clinical implications of telomerase activity in human brain tumors / Hyoung-Joon Chun ... [et al.]. 606 $aTelomere 606 $aTelomerase 615 0$aTelomere. 615 0$aTelomerase. 676 $a572.8/7 701 $aMancini$b Leonardo$01658130 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910823409503321 996 $aTelomeres$94011945 997 $aUNINA