LEADER 02368nam 2200409 450 001 9910823001403321 005 20230809223525.0 010 $a0-309-45332-1 010 $a0-309-45330-5 035 $a(CKB)3710000001141061 035 $a(MiAaPQ)EBC4833793 035 $a(EXLCZ)993710000001141061 100 $a20170419h20172017 uy 0 101 0 $aeng 135 $aurcnu|||||||| 181 $2rdacontent 182 $2rdamedia 183 $2rdacarrier 200 13$aAn evidence framework for genetic testing /$fNational Academies of Sciences, Engineering, and Medicine (U.S.) 210 1$aWashington, District of Columbia :$cThe National Academies Press,$d2017. 210 4$dİ2017 215 $a1 online resource (136 pages) 311 $a0-309-45329-1 320 $aIncludes bibliographical references. 330 $a"Advances in genetics and genomics are transforming medical practice, resulting in a dramatic growth of genetic testing in the health care system. The rapid development of new technologies, however, has also brought challenges, including the need for rigorous evaluation of the validity and utility of genetic tests, questions regarding the best ways to incorporate them into medical practice, and how to weigh their cost against potential short- and long-term benefits. As the availability of genetic tests increases so do concerns about the achievement of meaningful improvements in clinical outcomes, costs of testing, and the potential for accentuating medical care inequality. Given the rapid pace in the development of genetic tests and new testing technologies, An Evidence framework for genetic testing seeks to advance the development of an adequate evidence base for genetic tests to improve patient care and treatment. Additionally, this report recommends a framework for decision-making regarding the use of genetic tests in clinical care"--$cPublisher's description. 606 $aGene expression$xResearch$xMethodology 606 $aHuman chromosome abnormalities$xDiagnosis 615 0$aGene expression$xResearch$xMethodology. 615 0$aHuman chromosome abnormalities$xDiagnosis. 676 $a572.865 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910823001403321 996 $aAn evidence framework for genetic testing$94047674 997 $aUNINA