LEADER 04744nam 2200661Ia 450 001 9910822759303321 005 20210623195137.0 010 $a1-281-23942-9 010 $a9786611239428 010 $a0-387-73364-7 024 7 $a10.1007/978-0-387-73364-7 035 $a(CKB)1000000000398905 035 $a(EBL)371946 035 $a(OCoLC)261325349 035 $a(SSID)ssj0000166872 035 $a(PQKBManifestationID)11161937 035 $a(PQKBTitleCode)TC0000166872 035 $a(PQKBWorkID)10169355 035 $a(PQKB)10558166 035 $a(DE-He213)978-0-387-73364-7 035 $a(MiAaPQ)EBC371946 035 $a(Au-PeEL)EBL371946 035 $a(CaPaEBR)ebr10223342 035 $a(CaONFJC)MIL123942 035 $a(PPN)123744180 035 $a(EXLCZ)991000000000398905 100 $a20071009d2008 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aHair cell regeneration, repair, and protection$b[electronic resource] /$fRichard J. Salvi, Arthur N. Popper, Richard R. Fay, editors 205 $a1st ed. 2008. 210 $aNew York $cSpringer$dc2008 215 $a1 online resource (322 p.) 225 1 $aSpringer handbook of auditory research ;$vv. 33 300 $aDescription based upon print version of record. 311 $a0-387-73363-9 320 $aIncludes bibliographical references and index. 327 $aOverview: Regeneration and Repair -- Morphological Correlates of Regeneration and Repair in the Inner Ear -- Recovery of Function in the Avian Auditory System After Ototrauma -- Functional Recovery After Hair Cell Regeneration in Birds -- Hair Cell Regeneration: Mechanisms Guiding Cellular Proliferation and Differentiation -- Protection and Repair of Inner Ear Sensory Cells -- Gene Arrays, Cell Lines, Stem Cells, and Sensory Regeneration in Mammalian Ears. 330 $aThe sensory hair cells in the inner ear and vestibular system convert mechanical stimuli, sound and motion into neural activity that is responsible for the sensations of hearing, motion and head position. In mammals, the loss of hair cells from acoustic overstimulation, ototoxic drugs and aging is irreversible, leading to a permanent loss of function. However, it is now clear that hair cells in other vertebrates are capable of regenerating and recovering partial or complete function. Moreover, partially damaged hair cells can undergo self-repair or be protected from traumatic insults by external compounds. Hair Cell Regeneration, Repair, and Protection provides a comprehensive survey of what is currently known about the regeneration, repair and protection of sensory hair cells and subsequent recovery of function in the auditory and vestibular system. The aim is to provide graduate students, postdoctoral fellows, clinicians and scientists in related disciplines with the biological bases of hair cells and with an understanding of the factors that contribute to their regeneration and repair. Table of Contents: Overview: Regeneration and repair Richard J. Salvi Morphological Correlates of Regeneration and Repair in the Inner Ear Jason R. Meyers and Jeffrey T. Corwin The recovery of function in the avian auditory system following ototrauma James C. Saunders and Richard J. Salvi Functional recovery following hair cell regeneration in birds Robert J. Dooling, Micheal L. Dent, Amanda M. Lauer, and Brenda M. Ryals Hair cell regeneration: Mechanisms guiding cellular proliferation and differentiation Elizabeth C. Oesterle and Jennifer S. Stone Protection and repair of inner ear sensory cells Andrew Forge and Thomas R. Van De Water Gene arrays, cell lines, stem cells, and sensory regeneration in mammalian ears Marcelo N. Rivolta and Matthew C. Holley About the editors: Richard J. Salvi, Center for Hearing and Deafness, University of Buffalo, NY. Arthur N. Popper is Professor in the Department of Biology and Co-Director of the Center for Comparative and Evolutionary Biology of Hearing at the University of Maryland, College Park. Richard R. Fay is Director of the Parmly Hearing Institute and Professor of Psychology at Loyola University of Chicago. 410 0$aSpringer handbook of auditory research ;$vv. 33. 606 $aHair cells 606 $aHair cells$xRegeneration 615 0$aHair cells. 615 0$aHair cells$xRegeneration. 676 $a612.7/99 701 $aSalvi$b Richard$0290594 701 $aPopper$b Arthur N$0935643 701 $aFay$b Richard R$01562148 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910822759303321 996 $aHair cell regeneration, repair, and protection$94059804 997 $aUNINA