LEADER 05815nam 2200709 450 001 9910822629703321 005 20230803222448.0 010 $a1-118-84701-6 010 $a1-118-84694-X 010 $a1-118-84723-7 035 $a(CKB)2560000000148553 035 $a(EBL)1676381 035 $a(SSID)ssj0001181778 035 $a(PQKBManifestationID)11634854 035 $a(PQKBTitleCode)TC0001181778 035 $a(PQKBWorkID)11146171 035 $a(PQKB)10398450 035 $a(OCoLC)869847755 035 $a(MiAaPQ)EBC1676381 035 $a(DLC) 2014003283 035 $a(Au-PeEL)EBL1676381 035 $a(CaPaEBR)ebr10862633 035 $a(CaONFJC)MIL599913 035 $a(OCoLC)877771918 035 $a(EXLCZ)992560000000148553 100 $a20140506h20142014 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aRibosome-inactivating proteins $ericin and related proteins /$fedited by Fiorenzo Stirpe, Douglas A. Lappi 210 1$aAmes, Iowa ;$aChichester, England ;$aOxford, England :$cWiley,$d2014. 210 4$dİ2014 215 $a1 online resource (326 p.) 300 $aDescription based upon print version of record. 311 $a1-306-68662-8 311 $a1-118-12565-7 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $aRibosome-inactivating Proteins: Ricin and Related Proteins; Copyright; Contents; Contributors; Preface; 1 Introduction and History; Introduction; Identification and Distribution in Nature; Mechanism of Action; Effects on Cells and Animals; Role in Nature; Practical Applications; In Agriculture; In Medicine; Bioweapons; Future Challenges; References; 2 Occurrence and Taxonomical Distribution of Ribosome-inactivating Proteins Belonging to the Ricin/Shiga Toxin Superfamily; Introduction; How to Investigate the Distribution of Proteins with an N-glycosidase Domain? 327 $aOverview of the Occurrence of the N-glycosidase Domain in Living OrganismsPlant RIPs; Bacterial RIPs - Shiga Toxin Group; Distantly Related Non-secreted Protein Homolog of Stx A Subunit; RIPs in Actinobacteria; Fungal RIPs; Insect RIPs; Conclusions; Acknowledgments; References; 3 Ribosome-inactivating Proteins from Phytolaccaceae; Introduction; Physicochemical Properties and Structure; Enzymatic Activities of RIPs from Phytolaccaceae; Biological Activity; 4 Ribosome-inactivating Proteins in Caryophyllaceae, Cucurbitaceae, and Euphorbiaceae; Introduction; Caryophyllaceae RIPs; Agrostin 327 $aDianthinGypsophilin; Petroglaucin 1 and Petrograndin; Saporin; RIPs from Saponaria Ocymoides and Vaccaria Pyramidata; Cucurbitaceae RIPs; Bryodin; Colocin 1 and Colocin 2; Cucumis Melo; Cucurmosin; Hispin; Lagenin; Luffangulin; Luffa Cylindrica Protein Synthesis Inhibitors; Luffin; Luffacylin (Small RIP); LuffinS (Small RIP); Luffin P1 (Small RIP); Balsamin; Bitter Gourd Protein (MRK29); MAP30; Alpha- and Beta-Momorcharins; Charantin (Small RIP); Momorcochin; Cochinin B; Momorgrosvin; MOR-I and MOR-II; Moschatin; Cucurbita Moschata RIP; Pepocin; Sechiumin; Trichoanguin; Trichobitacin 327 $aTrichokirinTrichokirin-S1 (Small RIP); Trichomaglin; Trichosanthin; Karasurin-A, Karasurin-B, and Karasurin-C; Trichosanthrip (Small RIP); Euphorbiaceae RIPs; Croton Tiglium and Jatropha Curcas Protein Synthesis Inhibitors; Curcin; Gelonin; Lychnin; Mapalmin; Type 1 RIPs from other Families; Amaranthin (Family Amaranthaceae); Basella Rubra RIPs (Family Basellaceae) and Bougainvillea Spectabilis RIP (Family Nyctaginaceae); Beta Vulgaris RIP (Family Chamnopodiaceae); Nigritins f1 and f2 (Family Caprifoliaceae); Charybdin (Family Hyacinthaceae); Iris RIP (Family Iridaceae) 327 $aCamphorin (Family Lauraceae)Mirabilis Jalapa RIP (Family Nyctaginaceae); Barley (Family Poaceae); Wheat (Family Poaceae); Algal RIPs; Lamjapin (Family Laminariaceae); Fungal RIPs; Clavin (Family Trichocomaceae); Flammin and Velin (Family Tricholomataceae); Flammulin (Family Tricholomataceae); Hypsin (Family Tricholomataceae); Lyophyllin (Family Tricholomataceae); Marmorin (Family Tricholomataceae); Pleuturegin (Family Pleurotaceae); Velutin (Family Tricholomataceae); Volvarin (Family Plutaceae); Crystal Structures of RIPs; Production of Recombinant RIPs; Immunoreactivity of RIPs 327 $aEffects of Thiolation on the Immunoreactivity of the RIP gelonin 330 $a"This important reference provides up-to-date information on all aspects of ribosome-inactivating proteins (RIPs). Including a list of all known RIPs, their distribution in nature, structure, genetics and chemical and immunological properties, this reference covers mechanisms of action, including the enzymatic activity on various polynucleotide substrates; the interaction with, and entry into cells; the toxicity to animals, including the pathology of poisoning; and the immunomodulatory and allergenic activity. The book further emphasizes the use of immunotoxins and other conjugates in clinical trials for the therapy of cancer and intractable pain"--$cProvided by publisher. 330 $a"Ribosome-inactivating Proteins is a reference book which will provide up-to-date information on all aspects of ribosome-inactivating proteins (RIPs)"--$cProvided by publisher. 606 $aProteins$xSynthesis 606 $aRibosomes$xStructure 615 0$aProteins$xSynthesis. 615 0$aRibosomes$xStructure. 676 $a571.6/58 686 $aSCI017000$2bisacsh 702 $aLappi$b Douglas A. 702 $aStirpe$b Fiorenzo 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910822629703321 996 $aRibosome-inactivating proteins$94017440 997 $aUNINA