LEADER 02841nam 2200697Ia 450 001 9910822369803321 005 20200520144314.0 010 $a9781118354476 010 $a1118354478 010 $a9781118354483 010 $a1118354486 010 $a9781299464841 010 $a129946484X 010 $a9781118354469 010 $a111835446X 035 $a(CKB)2550000001019352 035 $a(EBL)1166776 035 $a(OCoLC)806456447 035 $a(SSID)ssj0000856037 035 $a(PQKBManifestationID)11470379 035 $a(PQKBTitleCode)TC0000856037 035 $a(PQKBWorkID)10805077 035 $a(PQKB)11433918 035 $a(MiAaPQ)EBC1166776 035 $a(DLC) 2012033430 035 $a(Au-PeEL)EBL1166776 035 $a(CaPaEBR)ebr10687828 035 $a(CaONFJC)MIL477734 035 $a(PPN)178874191 035 $a(Perlego)1001524 035 $a(EXLCZ)992550000001019352 100 $a20120813d2013 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aDrug discovery $epractices, processes, and perspectives /$fedited by Jie Jack Li, E.J. Corey 205 $a1st ed. 210 $aHoboken, N.J. $cJohn Wiley & Sons$dc2013 215 $a1 online resource (572 p.) 300 $aDescription based upon print version of record. 311 08$a9780470942352 311 08$a0470942355 320 $aIncludes bibliographical references and index. 327 $aHistory of drug discovery -- Target identification and validation -- In vitro and in vivo assays -- Drug metabolism and pharmacokinetics in drug discovery -- Cardiovascular drugs -- Diabetes drugs -- CNS drugs -- Cancer drugs -- Antiinflammatory and immunomodulatory drugs -- Anti-bacterial drugs -- Antiviral drug discovery. 330 $a Sets forth the history, state of the science, and future directions of drug discovery Edited by Jie Jack Li and Nobel laureate E. J. Corey, two leading pioneers in drug discovery and medicinal chemistry, this book synthesizes great moments in history, the current state of the science, and future directions of drug discovery into one expertly written and organized work. Exploring all major therapeutic areas, the book introduces readers to all facets and phases of drug discovery, including target selection, biological testing, drug metabolism, and computer-assisted drug design.