LEADER 04822nam 2200649 450 001 9910821834103321 005 20230808212514.0 010 $a0-8261-2913-7 035 $a(CKB)3710000000499920 035 $a(EBL)4102349 035 $a(SSID)ssj0001570614 035 $a(PQKBManifestationID)16220193 035 $a(PQKBTitleCode)TC0001570614 035 $a(PQKBWorkID)12218699 035 $a(PQKB)11207216 035 $a(MiAaPQ)EBC4102349 035 $a(Au-PeEL)EBL4102349 035 $a(CaPaEBR)ebr11121634 035 $a(CaONFJC)MIL838068 035 $a(OCoLC)932332605 035 $a(EXLCZ)993710000000499920 100 $a20151209h20162016 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aLashley's essentials of clinical genetics in nursing practice /$fChristine E. Kasper, Tonya A. Schneidereith, Felissa R. Lashley, editors 205 $aSecond edition. 210 1$aNew York, New York :$cSpringer Publishing Company,$d2016. 210 4$dİ2016 215 $a1 online resource (531 p.) 300 $aDescription based upon print version of record. 311 $a0-8261-2912-9 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $aCover; Title; Copyright; Contents; Contributors; Editor's Note; Preface; Reference; Share Lashley's Essentials of Clinicals Genetics in Nursing Practice: Second Edition; Part I: The Basics; Chapter 1: Genomics in Health Care; Human Genome Project; Increasing Genetic Literacy; Nursing Roles in a Genomic Era; Summary; Key Points; References; Bibliography; Chapter 2: Basic Concepts in Molecular Biology; Chromosomes; Cell Division; Chromosomes and Inheritance; Genes and DNA; Gene Expression; The Genetic Code; Gene Action and Expression; Mutations 327 $aMolecular Techniques and Tools for Detection and Diagnosis of Genetic DiseasesKey Points; References; Bibliography; Chapter 3: Human Diversity and Variation; We are Not All Genetically Identical; Genetic Individuality; Variations and Polymorphisms in Proteins; Variations and Polymorphisms in DNA; Maintenance of Variation and Polymorphism in Populations; Other Examples of Human Genetic Variation; Key Points; References; Bibliography; Chapter 4: Inheritance Patterns in Human Phenotypes and Types of Genetic Disorders; Inheritance Patterns of Human Phenotypes; Nontraditional Inheritance 327 $aSingle Gene Inherited Biochemical DisordersChromosomal Abnormalities; Factors in Numerical Chromosome Errors; Multifactorial Disorders; Environmental Disorders; Factors Affecting the Expression of the Phenotype; Summary; Questions for Discussion; References; Bibliography; Chapter 5: Prevention, Genetic Testing, and Treatment of Genetic Disease; Prevention; Genetic and Genomic Testing; Therapeutic Strategies Employed in Genetic Disorders; Key Points; References; Bibliography; Part II: The Integration of Genetics Into Nursing Curricula; Chapter 6: The Application of Genomics to Pharmacology 327 $aCommon Gene Mutations and Variations Affecting Drug MetabolismLess Common Single Gene Disorders with Pharmacogenetic Implications; Ethical, Legal, and Social Issues Related to Pharmacogenomics; Summary; Key Points and Questions for Discussion; Bibliography; Resources; Chapter 7: Assessing Patients With a Genetic "Eye": Family History and Physical Assessment; Family History; Pedigrees; Developmental and Physical Assessment; Suspecting a Genetic Component and Referral to a Geneticist; Key Points; Reference; Bibliography; Chapter 8: Maternal-Child Nursing: Obstetrics 327 $aPreconception or Prepregnancy CounselingPregnancy; The Vulnerable Fetus and Teratogenesis; Prenatal Detection and Diagnosis; Assisted Reproductive Techniques; Screening Gamete Donors; Newborn Screening; Conclusions; Social and Ethical Issues Associated with Screening; The Future; Key Points; Bibliography; Chapter 9: Maternal-Child Nursing: Pediatrics; Birth Defects; Chromosome Disorders; Inborn Errors of Metabolism; Selected Genetic Disorders Commonly Seen in Childhood; Hemoglobin and Its Inherited Variants; Key Points; Bibliography 327 $aChapter 10: Adult Health and Illness and Medical-Surgical Nursing 606 $aMedical genetics 606 $aNursing 615 0$aMedical genetics. 615 0$aNursing. 676 $a616/.042 700 $aLashley$b Felissa R.$f1941- ,$01095686 702 $aKasper$b Christine E. 702 $aSchneidereith$b Tonya A. 702 $aLashley$b Felissa R.$f1941- 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910821834103321 996 $aLashley's essentials of clinical genetics in nursing practice$94079298 997 $aUNINA