LEADER 02762nam 2200685 a 450 001 9910821507803321 005 20240516104827.0 010 $a9786613432131 010 $a9783527647989 010 $a3527647988 010 $a9781283432139 010 $a1283432137 010 $a9783527636778 010 $a3527636773 035 $a(CKB)2550000000079578 035 $a(EBL)837577 035 $a(OCoLC)773565121 035 $a(SSID)ssj0000621376 035 $a(PQKBManifestationID)12283784 035 $a(PQKBTitleCode)TC0000621376 035 $a(PQKBWorkID)10617430 035 $a(PQKB)10175523 035 $a(MiAaPQ)EBC837577 035 $a(Au-PeEL)EBL837577 035 $a(CaPaEBR)ebr10526571 035 $a(CaONFJC)MIL343213 035 $a(PPN)179385127 035 $a(Perlego)1004102 035 $a(EXLCZ)992550000000079578 100 $a20120217d2012 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aAlternative pre-mRNA splicing $etheory and protocols /$fedited by Stefan Stamm, Chris Smith, and Reinhard Lu?hrmann 205 $a1st ed. 210 $aWeinheim, Germany $cWiley-Blackwell$dc2012 215 $a1 online resource (662 p.) 300 $aDescription based upon print version of record. 311 08$a9783527636785 311 08$a3527636781 311 08$a9783527326068 311 08$a3527326065 320 $aIncludes bibliographical references and index. 327 $apt. 1. Theory -- pt. 2. Basic methods -- pt. 3. Detection of splicing events -- pt. 4. Analysis of splicing in vitro -- pt. 5. Analysis of splicing in vivo -- pt. 6. Manipulation of splicing events -- pt. 7. Bioinformatic analysis of splicing. 330 $aThis book was written for graduate and medical students, as well as clinicians and postdoctoral researchers. It describes the theory of alternative pre-mRNA splicing intwelve introductory chapters and then introduces protocols and their theoretical background relevant for experimental research. These 43 practical chapters cover: Basic methods, Detection of splicing events, Analysis of alternative pre-mRNA splicing in vitro and in vivo, Manipulation of splicing events, and Bioinformatic analysis of alternative splicing.A theoretical introduction and practical guide for molecular biologi 606 $aMessenger RNA 615 0$aMessenger RNA. 676 $a572.88 701 $aStamm$b Stefan$01665622 701 $aSmith$b Chris$0373829 701 $aLu?hrmann$b Reinhard$01665623 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910821507803321 996 $aAlternative pre-mRNA splicing$94024366 997 $aUNINA