LEADER 04888nam 2200661 450 001 9910821470003321 005 20200520144314.0 010 $a1-78242-087-8 010 $a1-78242-095-9 035 $a(CKB)3710000000499536 035 $a(EBL)4082037 035 $a(SSID)ssj0001586796 035 $a(PQKBManifestationID)16269761 035 $a(PQKBTitleCode)TC0001586796 035 $a(PQKBWorkID)14869387 035 $a(PQKB)10869599 035 $a(Au-PeEL)EBL4082037 035 $a(CaPaEBR)ebr11117796 035 $a(CaONFJC)MIL847040 035 $a(OCoLC)927969318 035 $a(MiAaPQ)EBC4082037 035 $a(EXLCZ)993710000000499536 100 $a20151123h20162016 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aCharacterisation and design of tissue scaffolds /$fedited by Paul Tomlins ; contributors, S. F. Badylak [and twenty others] 210 1$aAmsterdam, [Netherlands] :$cWoodhead Publishing,$d2016. 210 4$dİ2016 215 $a1 online resource (296 p.) 225 1 $aWoodhead Publishing Series in Biomaterials ;$vNumber 106 300 $aDescription based upon print version of record. 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $a""Front Cover""; ""Characterisation and Design of Tissue Scaffolds""; ""Copyright Page""; ""Contents""; ""List of contributors""; ""Woodhead publishing series in biomaterials""; ""1 Material types for tissue scaffolds""; ""Introduction""; ""Polymers""; ""Naturally occurring polymers""; ""Polysaccharides""; ""Alginates""; ""Chitosan""; ""Xanthan""; ""Proteins""; ""Collagen""; ""Fibrin and fibrinogen""; ""Hyaluronic acid""; ""Synthetic polymers""; ""Polyesters""; ""Polyethers""; ""Synthetic proteins""; ""Ceramics""; ""De-cellularized matrices""; ""Characterization of materials"" 327 $a""Sterilization""""Future trends""; ""Sources of further information""; ""References""; ""2 Designing and modeling pore size distribution in tissue scaffolds""; ""Background""; ""Modeling of pore architecture and its effect on the process of tissue engineering""; ""Selection of fabrication technique in terms of pore size distribution-with emphasis on polymer-based scaffolds""; ""Electrospinning of tissue engineered vascular grafts-the effect of pore morphology on the mechanical and biological functio...""; ""Conclusion""; ""References"" 327 $a""3 Computer modeling of the degradation behavior of polyester-based tissue engineering scaffolds""""Introduction""; ""Tissue engineering scaffolds""; ""Factors controlling the degradation rate of scaffolds""; ""Material factors""; ""The effect of geometry""; ""Environmental conditions""; ""A mathematical model for the degradation of bioresorbable polyesters""; ""Degradation maps""; ""Computer modeling of scaffold degradation using finite element methods""; ""FE modeling procedure""; ""Foamlike scaffolds""; ""Size effect zone""; ""Molecular weight""; ""Scission rate"" 327 $a""Short chain diffusion""""Fibrous scaffolds""; ""Size effect zone""; ""Molecular weight""; ""Scission rate""; ""Short chain diffusion""; ""Conclusion""; ""References""; ""4 Decellularization of mammalian tissues: preparing extracellular matrix bioscaffolds""; ""Introduction""; ""Rationale and relevance for clinical use of decellularized tissues""; ""Establishing a criteria for decellularization efficacy""; ""Decellularization agents""; ""Hypertonic and hypotonic solutions""; ""Acids and alkaline bases""; ""Acids""; ""Alkaline bases""; ""Detergents""; ""Nonionic detergents"" 327 $a""Ionic detergents""""Zwitterionic detergents""; ""Solvents""; ""Tri(n-butyl)phosphate""; ""Alcohols""; ""Biological agents""; ""Enzymes""; ""Nonenzymatic biologic agents""; ""Chelating agents""; ""Toxins""; ""Decellularization techniques""; ""Immersion and agitation""; ""Use of pressure as a decellularization technique""; ""Supercritical fluid""; ""Perfusion decellularization of whole organ constructs""; ""Terminal sterilization of decellularized tissues""; ""Decellularization agents that act as disinfectants""; ""Depyrogenation""; ""Ionizing radiation""; ""Ethylene oxide exposure"" 327 $a""Conclusion"" 410 0$aWoodhead Publishing series in biomaterials ;$vNumber 106. 606 $aTissue engineering$xMaterials 606 $aTissue scaffolds 606 $aBiomedical materials 615 0$aTissue engineering$xMaterials. 615 0$aTissue scaffolds. 615 0$aBiomedical materials. 676 $a610.284 702 $aTomlins$b Paul 702 $aBadylak$b S. F. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910821470003321 996 $aCharacterisation and design of tissue scaffolds$94083837 997 $aUNINA