LEADER 03689nam 2200589Ia 450 001 9910782388003321 005 20230607222142.0 010 $a1-281-95657-0 010 $a9786611956578 010 $a981-281-101-X 035 $a(CKB)1000000000537983 035 $a(StDuBDS)AH24685593 035 $a(SSID)ssj0000221431 035 $a(PQKBManifestationID)11192553 035 $a(PQKBTitleCode)TC0000221431 035 $a(PQKBWorkID)10161297 035 $a(PQKB)10996464 035 $a(MiAaPQ)EBC1681753 035 $a(WSP)00004774 035 $a(Au-PeEL)EBL1681753 035 $a(CaPaEBR)ebr10255448 035 $a(CaONFJC)MIL195657 035 $a(OCoLC)815755997 035 $a(EXLCZ)991000000000537983 100 $a20020214d2001 uy 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt 182 $cc 183 $acr 200 14$aThe physical foundation of protein architecture$b[electronic resource] /$fNobuhiko Saito, Yukio Kobayashi 210 $aSingapore ;$aRiver Edge, N.J. $cWorld Scientific$dc2001 215 $a1 online resource (156p. ) $cillustrations 300 $aBibliographic Level Mode of Issuance: Monograph 311 $a981-02-4710-9 320 $aIncludes bibliographical references (p. 135-142) and index. 327 $aGeneralities: helix-coil transition in polypeptide; some aspects of protein folding. Mechanism of protein folding: island model; a-helical proteins; lysozyme and phospholipase; bovine pancreatic trypsin inhibitor; flavodoxin and thioredoxin; ferredoxin. Folding of a protein of unknown structure: ab initio method of prediction of protein structure; search for the conformation of minimum energy. Topics related to protein structures: phase transition; module; molecular chaperones; membrane proteins; structure prediction based on protein data. 330 8 $aThis work elucidates the mechanism of various processes in protein folding. The main features of protein folding are shown to be described by the island model with long range hydrophobic interaction which is capable of finding the specific residue, and the lampshade criterion for disulfide bonding.$bA protein requires its own three-dimensional structure for its biological activity. If a chemical agent is added, the biological activity is lost, and the three-dimensional structure is destroyed to become a random coil state. But when the chemical agent is removed, the biological activity is recovered, implying that the random coil state turns back into the original complex structure spontaneously. This is an astonishing event.;"The Physical Foundation of Protein Architecture" is intended to solve this mystery from the physicochemical basis by elucidating the mechanism of various processes in protein folding. The main features of protein folding are shown to be described by the island model with long range hydrophobic interaction which is capable of finding the specific residue, and the lampshade criterion for disulfide bonding. Various proteins with known structure are refolded, with the purpose of uncovering the mechanism of protein folding. In addition, ab initio method for predicting protein structure from its amino acid sequence is proposed. 606 $aProteins$xStructure 606 $aBiomolecules$xStructure 615 0$aProteins$xStructure. 615 0$aBiomolecules$xStructure. 676 $a572.6 700 $aSaito?$b Nobuhiko$048405 701 $aKobayashi$b Yukio$0150970 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910782388003321 996 $aPhysical foundation of protein architecture$9471799 997 $aUNINA LEADER 03691oam 22008654a 450 001 9910819964203321 005 20221024203313.0 010 $a1-57506-355-7 024 7 $a10.1515/9781575063553 035 $a(CKB)3710000000374080 035 $a(EBL)3155730 035 $a(SSID)ssj0001550823 035 $a(PQKBManifestationID)16166086 035 $a(PQKBTitleCode)TC0001550823 035 $a(PQKBWorkID)14811189 035 $a(PQKB)10687369 035 $a(Au-PeEL)EBL3155730 035 $a(CaPaEBR)ebr11031271 035 $a(OCoLC)922991841 035 $a(DE-B1597)584500 035 $a(DE-B1597)9781575063553 035 $a(OCoLC)1273306038 035 $a(MdBmJHUP)musev2_80851 035 $a(MiAaPQ)EBC3155730 035 $a(OCoLC)1253313024 035 $a(EXLCZ)993710000000374080 100 $a20150311d2014 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aBabel und Bibel 8$eStudies in Sumerian Language and Literature: Festschrift Joachim Krecher /$fedited by N. Koslova, E. Vizirova, and G. Zo?lyomi 210 1$aWinona Lake, Indiana :$cEisenbrauns,$d2014. 210 4$d©2014. 215 $a1 online resource (669 p.) 225 0 $aOrientalia et classica ;$vvol. LVI 225 0 $aBabel und Bibel ;$v8 300 $aDescription based upon print version of record. 311 $a1-57506-354-9 320 $aIncludes bibliographical references at the end of each chapters. 327 $a""Blank Page"" 330 $aThis is the eighth volume of Babel und Bibel, an annual of ancient Near Eastern, Old Testament, and Semitic studies. The principal goal of the annual is to reveal the inherent relationship between Assyriology, Semitics, and biblical studies?a relationship that our predecessors comprehended and fruitfully explored but that is often neglected today. The title Babel und Bibel is intended to point to the possibility of fruitful collaboration among the three disciplines, in an effort to explore the various civilizations of the ancient Near East.This volume is a festschrift for Joachim Krecher, Professor of Assyriology in the Westfälische Wilhelms-Universität Münster. Krecher is best known, perhaps, for his seminal Sumerische Kultlyrik, published already in 1966. This compendium includes 17 essays by friends and colleagues, all focusing on Sumerian language and literature. 410 0$aOrientalia et classica ;$vVolume LVI. 410 0$aBabel und Bibel ;$v8. 606 $aSumerian language$2fast$3(OCoLC)fst01138450 606 $aSemitic philology$2fast$3(OCoLC)fst01112420 606 $aMiddle Eastern philology$2fast$3(OCoLC)fst01020346 606 $aPhilologie se?mitique 606 $aSemitic philology 606 $aPhilologie moyen-orientale 606 $aMiddle Eastern philology 606 $aSume?rien (Langue) 606 $aSumerian language 608 $aCriticism, interpretation, etc. 615 7$aSumerian language. 615 7$aSemitic philology. 615 7$aMiddle Eastern philology. 615 7$aPhilologie se?mitique. 615 7$aSemitic philology. 615 7$aPhilologie moyen-orientale. 615 7$aMiddle Eastern philology. 615 7$aSume?rien (Langue) 615 7$aSumerian language. 676 $a499.95 702 $aZo?lyomi$b Ga?bor 702 $aVizirova$b E. 702 $aKoslova$b Natalia V. 712 02$aRossii?skii? gosudarstvennyi? gumanitarnyi? universitet. 801 0$bMdBmJHUP 801 1$bMdBmJHUP 906 $aBOOK 912 $a9910819964203321 996 $aBabel und Bibel 8$93942052 997 $aUNINA