LEADER 03557nam 2200565Ia 450 001 9910819729803321 005 20200520144314.0 010 $a0-429-18086-1 010 $a1-4822-6735-7 010 $a0-203-99989-4 024 7 $a10.1201/9781482267358 035 $a(CKB)1000000000001745 035 $a(SSID)ssj0000431909 035 $a(PQKBManifestationID)11295000 035 $a(PQKBTitleCode)TC0000431909 035 $a(PQKBWorkID)10476566 035 $a(PQKB)11240696 035 $a(MiAaPQ)EBC3059125 035 $a(Au-PeEL)EBL3059125 035 $a(CaPaEBR)ebr10017621 035 $a(OCoLC)712629045 035 $a(EXLCZ)991000000000001745 100 $a19930527d1993 uy 0 101 0 $aeng 135 $aurcn||||||||| 181 $ctxt 182 $cc 183 $acr 200 10$aControlled drug release of oral dosage forms /$fJean-Maurice Vergnaud 205 $aFirst edition. 210 $aNew York $cE. Horwood$d1993 215 $axii, 410 p. $cill 225 1 $aEllis Horwood series in pharmaceutical technology 300 $aBibliographic Level Mode of Issuance: Monograph 311 $a0-13-174954-4 320 $aIncludes bibliographical references and index. 327 $aPart 1 Mathematical treatment of diffusion: the plane dosage forms; cylinder of finite length; spherical dosage forms. Part 2 Numerical analysis for diffusion: plane dosage forms; cylinder of finite length; spherical dosage forms; other shapes; one or two matter transfers; models taking into account the swelling of the polymer matrix. Part 3 Description of various oral dosage forms: drug dispersed in a non-erodible polymer matrix, plane, spherical; drug dispersed in an erodible polymer matrix; dosage forms made of a core and shell, with an erodible shell; dosage forms made of a core and shell, with a non-erodible shell; dosage forms able to deliver the drug when the solubility of the drug is very low; problem of drying dosage forms made of drug and polymer. 330 2 $a"Numerical analysis of matter transfer is an area that pharmacists find difficult, but which is a technique frequently used in preparing controlled drug release and oral dosage forms. This book provides clear and straightforward information enabling the reader to carry out numerical analysis of matter transfer - a vital processs when looking at the formulation of oral dosage forms with controlled drug release. The drug is dispersed in a polymeric matrix either biodegradable or not, the basis of which is the transfer of the liquid and the drug through dosage form. Information on this diffusion is found either through mathematical treatment when the problem is simple, or through numerical analysis for more complex problems. Professor Vergnaud demonstrates and clarifies these, modelling the process of drug delivery by using numerical analysis and computerization. A simulation of the process is provided, together with a determination of the effects of all parameters, and the author uses both mathematical and numerical models to predict the preparation of new dosage forms able to fulfil specific conditions."--Provided by publisher. 410 0$aEllis Horwood series in pharmaceutical technology. 606 $aOral medication 615 0$aOral medication. 676 $a615/.6 700 $aVergnaud$b J. M$0753628 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910819729803321 996 $aControlled Drug Release Of Oral Dosage Forms$93930223 997 $aUNINA