LEADER 02175oam  2200493   450 
001 9910819352403321
005 20190911100031.0
010   $a0-12-800837-7
010   $a0-12-800994-2
035   $a(OCoLC)929781344
035   $a(MiFhGG)GVRL6QDP
035   $a(EXLCZ)993710000000483058
100   $a20160222h20162016  uy             0
101 0 $aeng
135   $aurun|---uuuua
181   $ctxt
182   $cc
183   $acr
200 10$aVirus as populations $ecomposition, complexity, dynamics, and biological implications /$fEsteban Domingo, Centro de Biologia Molecular Severo, Ochoa (CSIC-UAM), University Automona de Madrid, Cantoblanco, Madrid, Spain
205   $aFirst edition.
210  1$aLondon :$cAcademic Press,$d[2016]
210  4$d?2016
215   $a1 online resource (xvi, 412 pages) $cillustrations (some color)
225 0 $aGale eBooks
300   $aDescription based upon print version of record.
320   $aIncludes bibliographical references and index.
327   $aIntroduction to virus origins and their role in biological evolution -- Molecular basis of genetic variation of viruses : error-prone replication -- Darwinian principles acting on highly mutable viruses -- Interaction of virus populations with their hosts -- Viral fitness as a measure of adaptation -- Virus population dynamics examined with experimental model systems -- Long-term virus evolution in nature -- Quasispecies dynamics in disease prevention and control -- Trends in antiviral strategies -- Collective population effects in nonviral systems.
330   $aThis book explains fundamental concepts that arise from regarding viruses as complex populations when replicating in infected hosts.
606   $aViruses$xEvolution
606   $aViruses
606   $aVirology
606   $aViral genetics
615  0$aViruses$xEvolution.
615  0$aViruses.
615  0$aVirology.
615  0$aViral genetics.
676   $a576.64
700   $aDomingo$b Esteban$01658741
801  0$bMiFhGG
801  1$bMiFhGG
906   $aBOOK
912   $a9910819352403321
996   $aVirus as populations$94012953
997   $aUNINA