LEADER 04531nam 2200757Ia 450 001 9910819263803321 005 20200520144314.0 010 $a1-107-14931-2 010 $a1-280-47791-1 010 $a9786610477913 010 $a0-511-19533-8 010 $a0-511-19599-0 010 $a0-511-19393-9 010 $a0-511-31434-5 010 $a0-511-54522-3 010 $a0-511-19467-6 035 $a(CKB)1000000000353122 035 $a(EBL)259897 035 $a(OCoLC)171138791 035 $a(SSID)ssj0000257442 035 $a(PQKBManifestationID)11215216 035 $a(PQKBTitleCode)TC0000257442 035 $a(PQKBWorkID)10253994 035 $a(PQKB)11604189 035 $a(UkCbUP)CR9780511545221 035 $a(MiAaPQ)EBC259897 035 $a(Au-PeEL)EBL259897 035 $a(CaPaEBR)ebr10130350 035 $a(CaONFJC)MIL47791 035 $a(OCoLC)560222948 035 $a(PPN)261293303 035 $a(EXLCZ)991000000000353122 100 $a20040114d2004 uy 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aTestosterone $eaction, deficiency, substitution /$fedited by E. Nieschlag, H.M. Behre, S. Nieschlag 205 $a3rd ed. 210 $aCambridge, U.K. ;$aNew York, NY, USA $cCambridge University Press$dc2004 215 $a1 online resource (xiii, 747 pages) $cdigital, PDF file(s) 300 $aTitle from publisher's bibliographic system (viewed on 05 Oct 2015). 311 $a0-521-83380-9 320 $aIncludes bibliographical references and index. 327 $aCover; Half-title; Title; Copyright; Contents; Contributors; Preface; 1 Testosterone: an overview of biosynthesis, transport, metabolism and non-genomic actions; 2 The androgen receptor: molecular biology; 3 Androgen receptor: pathophysiology; 4 Behavioural correlates of testosterone; 5 The role of testosterone in spermatogenesis; 6 Androgens and hair: a biological paradox; 7 Androgens and bone metabolism; 8 Testosterone effects on the skeletal muscle; 9 Androgens and Erythropoiesis; 10 Testosterone and cardiovascular diseases; 11 Testosterone and erection; 12 Testosterone and the prostate 327 $a13 Clinical uses of testosterone in hypogonadism and other conditions14 Pharmacology of testosterone preparations; 15 Androgen therapy in non-gonadal disease; 16 Androgens in male senescence; 17 The pathobiology of androgens in women; 18 Clinical use of 5alpha-reductase inhibitors; 19 Dehydroepiandrosterone (DHEA) and androstenedione; 20 Selective androgen receptor modulators (SARMs); 21 Methodology for measuring testosterone, DHT and SHBG in a clinical setting; 22 Synthesis and pharmacological profiling of new orally active steroidal androgens 327 $a23 Hormonal male contraception: the essential role of testosterone24 Abuse of androgens and detection of illegal use; Subject index 330 $aThis book provides information on testosterone and other androgens, and their role in human physiology and pathology. It covers biosynthesis and mechanisms of action and reviews their effects on brain and behaviour, spermatogenesis, hair growth, bones, muscles, erythropoiesis, the cardiovascular system and lipids, erection, and the prostate. Therapeutic uses of testosterone preparations are carefully evaluated, including use in women, the aging male, and its abuse and detection in sport. The book reviews applications in male contraception, the role of 5a-reductase inhibitors and the controversial use of DHEA. For this book the editors have assembled the world leaders in testosterone research and clinical andrology and endocrinology. A special feature of the book is the fact that its 24 chapters were submitted simultaneously to insure rapid publication. This revised and significantly expanded edition will serve as the standard source of reference for many years. 606 $aTestosterone$xTherapeutic use 606 $aTestosterone$xPhysiological effect 606 $aAndrogens 615 0$aTestosterone$xTherapeutic use. 615 0$aTestosterone$xPhysiological effect. 615 0$aAndrogens. 676 $a615/.366 701 $aNieschlag$b E$01435995 701 $aBehre$b H. M$g(Hermann M.),$f1961-$01435996 701 $aNieschlag$b S$g(Susan)$01435998 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910819263803321 996 $aTestosterone$94200157 997 $aUNINA