LEADER 03474nam 2200685Ia 450 001 9910819213003321 005 20230607213027.0 010 $a1-280-04311-3 010 $a9786610043118 010 $a0-306-46848-4 024 7 $a10.1007/b111097 035 $a(CKB)111056485441784 035 $a(EBL)3035552 035 $a(SSID)ssj0000250604 035 $a(PQKBManifestationID)11176343 035 $a(PQKBTitleCode)TC0000250604 035 $a(PQKBWorkID)10232688 035 $a(PQKB)10327496 035 $a(DE-He213)978-0-306-46848-3 035 $a(MiAaPQ)EBC3035552 035 $a(MiAaPQ)EBC197146 035 $a(Au-PeEL)EBL3035552 035 $a(CaPaEBR)ebr10048313 035 $a(CaONFJC)MIL4311 035 $a(OCoLC)49852206 035 $a(Au-PeEL)EBL197146 035 $a(OCoLC)228373481 035 $a(EXLCZ)99111056485441784 100 $a20010214d2002 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aStaphylococcus aureus infection and disease /$fedited by Allen Honeyman, Herman Friedman and Mauro Bendinelli 205 $a1st ed. 2001. 210 $aNew York $cKluwer Academic$dc2002 215 $a1 online resource (351 p.) 225 1 $aInfectious agents and pathogenesis 300 $aDescription based upon print version of record. 311 $a0-306-46591-4 320 $aIncludes bibliographical references and index. 327 $aThe Regulation of Virulence in the Staphylococci -- Small Colony Variants of Staphylococcus aureus: Mechanisms for Production, Biology of Infection, and Clinical Significance -- Capsule Production -- Capsule and Vaccine Development -- Superantigen Activation of Macrophages -- Toxin Production -- Staphylococcal Enterotoxins -- Staphylococcal Extracellular/ Surface Enzymatic Activity -- Surface Protein Anchoring and Display in Staphylococci -- Pore-forming Cytolysins ? and ?-Hemolysins and Leukocidin from Staphylococcus aureus -- Osteomyelitis and Septic Arthritis -- Internalization of Staphylococcus aureus by Nonprofessional Phagocytes -- Staphylococcus aureus Mastitis -- Global Regulation of Virulence Determinants in Staphylococcus aureus. 330 $aStaphylococcus aureus is now acknowledged as being the most important bacterial pathogen of humans. It usually produces localized disease but can be rapidly invasive, spreading through the tissues, invading bone, and seeding the bloodstream to produce a fulminant picture of septic shock, disseminated intravascular coagulation, and rapid death. Moreover, most strains of staph infections are becoming resistant to most antibiotics, thus posing a significant problem for hospitals and health care facilities. This book, a volume in the Infectious Agents and Pathogenesis series, presents chapters by the major researchers in the field. 410 0$aInfectious agents and pathogenesis. 606 $aStaphylococcus aureus infections 606 $aPathogenic microorganisms 615 0$aStaphylococcus aureus infections. 615 0$aPathogenic microorganisms. 676 $a616/.01453 701 $aHoneyman$b Allen$01717318 701 $aFriedman$b Herman$f1931-2007.$01648774 701 $aBendinelli$b Mauro$0291109 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910819213003321 996 $aStaphylococcus aureus infection and disease$94113437 997 $aUNINA