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100   $a20030422d2004      uy         0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 00$aOncogenomics $emolecular approaches to cancer /$fedited by Charles Brenner, David J. Duggan
205   $a1st ed.
210   $aHoboken $cWiley-Liss$dc2004
215   $a1 online resource (411 p.)
300   $aDescription based upon print version of record.
311 08$a9780471225928 
311 08$a0471225924 
320   $aIncludes bibliographical references and index.
327   $aCONTENTS; Contributors; Preface; Section I INTRODUCTION; 1 AT THE PRECARIOUS CUSP OF ONCOGENOMICS; Section II MOLECULAR PROFILING IN CANCER: DNA, RNA, AND PROTEIN; 2 GENOME-WIDE SEARCHES FOR MUTATIONS IN HUMAN CANCER; 3 MOLECULAR CYTOGENETICS: INCREASING RESOLUTION USING ARRAY-BASED CGH; 4 SNPs AND FUNCTIONAL POLYMORPHISMS IN CANCER; 5 EXPRESSION PROFILING OF BREAST CANCER: FROM MOLECULAR PORTRAITS TO CLINICAL UTILITY; 6 CLASSIFYING HEREDITARY CANCERS AND PHENOCOPIES OF HEREDITARY CANCERS USING EXPRESSION ARRAYS
327   $a7 LINKING DRUGS AND GENES: PHARMACOGENOMICS, PHARMACOPROTEOMICS, BIOINFORMATICS, AND THE NCI-608 TISSUE MICROANALYSIS: PROFILING CANCER STAGES; 9 PROTEOMICS IN BLADDER CANCER; Section III MODEL SYSTEMS; 10 CHEMICAL AND GENETIC METHODS TO VALIDATE TARGETS IN NONMAMMALIAN ORGANISMS; 11 MOUSE MODELS OF CANCER; 12 GENOME-WIDE MODIFIER SCREENS: HOW THE GENETICS OF CANCER PENETRANCE MAY SHAPE THE FUTURE OF PREVENTION AND TREATMENT; Section IV MOLECULARLY TARGETED DRUGS; 13 PROTEIN KINASES AS TARGETS IN CANCER THERAPY: VALIDATED AND EMERGING APPROACHES; 14 RAS SUPERFAMILY-DIRECTED COMPOUNDS
327   $a15 CLINOMICS: POSTGENOMIC CANCER CARESection V CONCLUSION; 16 ONCOGENOMICS AND THE NCI DIRECTOR'S VISION FOR 2015; INDEX
330   $aThis book aims to assemble the only available rigorous, yet broadly accessible introduction to this new and exciting field. Oncogenomics: Molecular Approaches to Cancer is approachable by basic scientists, practitioners, and other health professionals required to familiarize themselves with the tremendous impact of genomics and proteomics on cancer research. Clearly written chapters offer reviews of state of the art topics such as molecular classification, early detection, SNPs in cancer, data mining, tissue microarrays, protein and antibody arrays, and drug targets.
606   $aCancer$xGenetic aspects
606   $aCancer$xMolecular aspects
606   $aGenomics
606   $aProteomics
606   $aOncogenes
615  0$aCancer$xGenetic aspects.
615  0$aCancer$xMolecular aspects.
615  0$aGenomics.
615  0$aProteomics.
615  0$aOncogenes.
676   $a616.99/4042
701   $aBrenner$b Charles$f1913-2008.$056577
701   $aDuggan$b David$01714102
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801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
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996   $aOncogenomics$94107632
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