LEADER 03706nam 2200637 450 001 9910818956103321 005 20230807213621.0 010 $a0-19-936462-1 010 $a0-19-936461-3 035 $a(CKB)3710000000356151 035 $a(EBL)1962961 035 $a(SSID)ssj0001437902 035 $a(PQKBManifestationID)12633611 035 $a(PQKBTitleCode)TC0001437902 035 $a(PQKBWorkID)11372987 035 $a(PQKB)11410540 035 $a(MiAaPQ)EBC1962961 035 $a(Au-PeEL)EBL1962961 035 $a(CaPaEBR)ebr11021971 035 $a(CaONFJC)MIL731276 035 $a(OCoLC)903584734 035 $a(EXLCZ)993710000000356151 100 $a20150227h20152015 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 14$aThe ethics police? $ethe struggle to make human research safe /$fRobert L. Klitzman 210 1$aNew York, New York :$cOxford University Press,$d2015. 210 4$dİ2015 215 $a1 online resource (433 p.) 300 $aIncludes index. 311 $a1-322-99994-5 311 $a0-19-936460-5 327 $aCover; Series; The Ethics Police?; Copyright; Dedication; Contents; Part I Introduction; Chapter 1. Protecting the People We Experiment On; Part II Who IRBs Are; Chapter 2. "Inside the Black Box": Becoming and Being IRB Members; Part III What IRBs Do: The Contents of IRB Decisions; Chapter 3. Weighing Risks and Benefits, and Undue Inducement; Chapter 4. Defining Research and How Good It Needs to Be; Chapter 5. What to Tell Subjects: Battles over Consent Forms; Chapter 6. From "Nitpicky" to "User-Friendly": Inter-IRB Variations and Their Causes 327 $aPart IV IRBs vs. Institutions: The Contexts of DecisionsChapter 7. Federal Agencies vs. Local IRBs; Chapter 8. The Roles of Industry; Chapter 9. The Local Ecologies of Institutions; Part V IRBs vs. Researchers; Chapter 10. Trusting vs. Policing Researchers; Chapter 11. Bad Behavior: Research Integrity; Chapter 12. Researchers Abroad: Studies in the Developing World; Part VI The Future; Chapter 13. Changing National Policies; Chapter 14. Conclusions: Other Changes; Appendices; Appendix A Additional Methodological Information; Appendix B Sample Semistructured Interview Questions 327 $aAppendix C AcronymsSources; Acknowledgments; Notes; Index 330 $aResearch on human beings saves countless lives, but has at times harmed the participants. To what degree then should government regulate science, and how? The horrors of Nazi concentration camp experiments and the egregious Tuskegee syphilis study led the US government, in 1974, to establish Research Ethics Committees, known as Institutional Review Boards (IRBs) to oversee research on humans. The US now has over 4,000 IRBs, which examine yearly tens of billions of dollars of research -- all studies on people involving diseases, from cancer to autism, and behavior. Yet ethical violations persis 606 $aHuman experimentation in medicine$xMoral and ethical aspects$zUnited States 606 $aResearch$xMoral and ethical aspects$zUnited States 606 $aEthics Committees, Research$zUnited States 606 $aGovernment Regulation$zUnited States 615 0$aHuman experimentation in medicine$xMoral and ethical aspects 615 0$aResearch$xMoral and ethical aspects 615 0$aEthics Committees, Research 615 0$aGovernment Regulation 676 $a174.2/8 700 $aKlitzman$b Robert$01086748 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910818956103321 996 $aThe ethics police$93968432 997 $aUNINA