LEADER 04541nam 2200721 a 450 001 9910818862303321 005 20240516064821.0 010 $a9786613693938 010 $a9780470720233 010 $a0470720239 010 $a9781280783548 010 $a1280783540 010 $a9780470717912 010 $a0470717912 035 $a(CKB)1000000000688090 035 $a(SSID)ssj0000715204 035 $a(PQKBManifestationID)11454821 035 $a(PQKBTitleCode)TC0000715204 035 $a(PQKBWorkID)10700429 035 $a(PQKB)10195107 035 $a(MiAaPQ)EBC703865 035 $a(Au-PeEL)EBL703865 035 $a(CaPaEBR)ebr10575679 035 $a(CaONFJC)MIL369393 035 $a(OCoLC)797918363 035 $a(OCoLC)2048134 035 $a(FINmELB)ELB179125 035 $a(Perlego)2766646 035 $a(EXLCZ)991000000000688090 100 $a20760129d1976 uy 0 101 0 $aeng 135 $aurcn||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aPolypeptide hormones $emolecular and cellular aspects /$feditors, F. G. Young [et al.] 205 $a1st ed. 210 $aAmsterdam ;$aNew York $cElsevier$d1976 210 1$aAmsterdam ;$aNew York :$cElsevier,$d1976. 215 $a1 online resource (xii, 388 pages) $cillustrations 225 1 $aCiba Foundation symposium (new series) ;$v41 300 $a"Symposium on the Polypeptide Hormones: Molecular and Cellular Aspects held at the Ciba Foundation, London, 1st-3rd July, 1975"--Participants page. 300 $a"In honour of Sir Frank Young." 311 0 $a9780470663332 311 0 $a0470663332 311 0 $a9789021940465 311 0 $a9021940469 320 $aIncludes bibliographical references and indexes. 327 $aPolypeptide Hormones: molecular and cellular aspects -- Contents -- Chairman's opening remarks -- Biosynthesis of insulin and glucagon: a view of the current state of the art -- Discussion -- Molecular evolution of the polypeptide hormones -- Discussion -- Prohormones of ?-melanotropin (?-melanocyte-stimulating hormone, ?-MSH) and corticotropin (adrenocorticotropic hormone, ACTH) : structure and activation -- Discussion -- The nature of pituitary large growth hormone as studied by immunoabsorption -- Discussion -- Isolation of a biologically active messenger RNA : preparation from fish pancreatic islets by oligo(2'-deoxyrhymidylic acid) affinity chromatography -- Discussion -- The control of insulin release by sugars -- Discussion -- The mode of action of adenosine 3': 5'-cyclic phosphate in the regulation of insulin secretion -- Discussion -- Multiple forms of corticotropin (adrenocorticotropic hormone, ACTH) and their significance -- Discussion -- Carboxypeptidase B-like and trypsin-like activities in isolated rat pancreatic islets -- Discussion -- New concepts in the formation, regulation of release, and metabolism of parathyroid hormone -- Discussion -- Structure and structure-function relationships in glycoprotein hormones -- Discussion -- Heterogeneity of the gastrins in blood and tissue -- Discussion -- Membrane topology as revealed by the binding of macromolecules -- Discussion -- Protein phosphorylation and hormone action -- Discussion -- Growth-promoting actions of peptide hormones -- Discussion -- General discussion I : Somatostatin-clinical implications Cells containing somatostatin in the pancreas and the gastrointestinal tract -- Gastrointestinal effects of somatostatin -- Somatostatin and diabetes mellitus -- General discussion II: Peptide metabolism -- Post-synthetic modification of peptides -- Secretion and processing. 327 $aClosing remarks -- Index of contributors -- Subject index. 330 8 $aThe Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world. 410 0$aCiba Foundation symposium ;$vnew ser. 41. 606 $aPeptide hormones$vCongresses 615 0$aPeptide hormones 676 $a599/.01/927 701 $aYoung$b Frank$0939223 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910818862303321 996 $aPolypeptide hormones$92117157 997 $aUNINA