LEADER 03966nam 2200709 a 450 001 9910818860903321 005 20240516065005.0 010 $a9786613694232 010 $a9780470720578 010 $a0470720573 010 $a9781280783845 010 $a1280783842 010 $a9780470718254 010 $a0470718250 035 $a(CKB)1000000000688126 035 $a(StDuBDS)AH13351468 035 $a(SSID)ssj0000715465 035 $a(PQKBManifestationID)11434947 035 $a(PQKBTitleCode)TC0000715465 035 $a(PQKBWorkID)10703791 035 $a(PQKB)10390856 035 $a(MiAaPQ)EBC703896 035 $a(Au-PeEL)EBL703896 035 $a(CaPaEBR)ebr10575660 035 $a(CaONFJC)MIL369423 035 $a(OCoLC)797918455 035 $a(Perlego)2758618 035 $a(EXLCZ)991000000000688126 100 $a19800221d1980 uy 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt 182 $cc 183 $acr 200 10$aDrug concentrations in neuropsychiatry 205 $a1st ed. 210 $aAmsterdam ;$aNew York $cExcerpta Medica ;$aNew York, N.Y. $cElsevier/North-Holland$d1980 215 $a1 online resource (192 p.) 225 1 $aCiba Foundation symposium (new series) ;$v74 300 $a"Symposium on Drug Concentrations in Neuropsychiatry, held at the Ciba Foundation, London, 4th-5th July 1979"--Participants page. 311 08$a9780470663851 311 08$a0470663855 311 08$a9780444901378 311 08$a044490137X 320 $aIncludes bibliographical references and indexes. 327 $aIntro -- Drug Concentrations in Neuropsychiatry -- Contents -- Introduction: The rational use of plasma drug levels in clinical medicine -- Discussion -- Principles of pharmacokinetics -- Discussion -- Methodological pitfalls: the influence of experimental design on results -- Discussion -- Interpretation of drug levels: relevance of plasma binding -- Discussion -- Quality control of drug assays -- Discussion -- Lithium concentrations and clinical responses -- Discussion -- Blood levels of flupenthixol in patients with acute and chronic schizophrenia -- Discussion -- Clinical significance of monitoring plasma levels of psychotropic drugs -- Discussion -- Benzodiazepines: some aspects of their clinical pharmacology -- Discussion -- Adrenergic and serotonergic mechanisms in depression and their response to amitriptyline -- Discussion -- The role of plasma level monitoring of tricyclic antidepressant drugs as an aid to treatment -- Discussion -- Clinical application of the monitoring of anticonvulsant drug levels -- Discussion -- The logistics of drug monitoring -- Discussion -- Alternative approaches -- Discussion -- GENERAL DISCUSSION -- Statistics and experimental design -- Further research on drug levels -- A guide for the doctor -- Concluding remarks -- Appendix Monitoring plasma concentrations of psychotropic drugs as an aid to treatment -- Index of contributors -- Subject index. 330 8 $aThe Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world. 410 0$aCiba Foundation symposium ;$vnew ser. 74. 606 $aNeuropsychopharmacology$vCongresses 606 $aPsychotropic drugs$vCongresses 615 0$aNeuropsychopharmacology 615 0$aPsychotropic drugs 676 $a616.89/18 712 02$aCiba Foundation. 712 12$aSymposium on Drug Concentrations in Neuropsychiatry 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910818860903321 996 $aDrug concentrations in neuropsychiatry$91963084 997 $aUNINA