LEADER 00771nam1 22002531i 450 001 SUN0029323 005 20100903120000.0 100 $a20041202d1992 |0itac50 ba 101 $aita 102 $aIT 105 $a|||| ||||| 200 1 $aOpere$fCesare Arzelą$ga cura dell'Unione matematica italiana 210 $aBologna$cEdizioni Cremonese$d1992 215 $a2 v.$d24 cm. 463 \1$1001SUN0029324$12001 $a<<>>Opere 1 463 \1$1001SUN0029325$12001 $a<<>>Opere 2 620 $dBologna$3SUNL000003 700 1$aArzelą$b, Cesare$3SUNV024226$0104907 712 02$aUnione matematica italiana$3SUNV020871 712 $aCremonese$3SUNV001098$4650 801 $aIT$bSOL$c20181109$gRICA 912 $aSUN0029323 996 $aOpere$91406240 997 $aUNICAMPANIA LEADER 04980nam 2200637 450 001 9910818706403321 005 20230807221130.0 010 $a0-309-31655-3 010 $a0-309-31653-7 035 $a(CKB)3710000000450897 035 $a(EBL)3439784 035 $a(SSID)ssj0001606584 035 $a(PQKBManifestationID)16317014 035 $a(PQKBTitleCode)TC0001606584 035 $a(PQKBWorkID)14896842 035 $a(PQKB)10237016 035 $a(MiAaPQ)EBC3439784 035 $a(Au-PeEL)EBL3439784 035 $a(CaPaEBR)ebr11091693 035 $a(OCoLC)928987538 035 $a(EXLCZ)993710000000450897 100 $a20150903h20152015 uy| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt 182 $cc 183 $acr 200 00$aIndustrialization of biology $ea roadmap to accelerate the advanced manufacturing of chemicals /$fCommittee on Industrialization of Biology: A Roadmap to Accelerate the Advanced Manufacturing of Chemicals, Board on Chemical Sciences and Technology, Board on Life Sciences, Division on Earth and Life Studies, National Research Council of the National Academies 210 1$aWashington, District of Columbia :$cThe National Academies Press,$d[2015] 210 4$d©2015 215 $a1 online resource (176 p.) 300 $aDescription based upon print version of record. 311 $a0-309-31652-9 320 $aIncludes bibliographical references. 327 $aFront Matter; Preface; Acknowledgment of Reviewers; Contents; Summary; 1 Introduction and Context; 2 Industrial Biotechnology: Past and Present; 3 Vision of the Future: What New Chemicals Could Be Made?; 4 How Do We Get There?; 5 What Is Success and How to Get There: Recommendations; References; Appendix A: Glossary; Appendix B: The Current Regulatory Framework; Appendix C: Committee Member and Staff Biographies; Appendix D: Workshop Agenda and Attendees; Figures S-1 and 5-1 (foldout) 330 $a"The tremendous progress in biology over the last half century - from Watson and Crick's elucidation of the structure of DNA to today's astonishing, rapid progress in the field of synthetic biology - has positioned us for significant innovation in chemical production. New bio-based chemicals, improved public health through improved drugs and diagnostics, and biofuels that reduce our dependency on oil are all results of research and innovation in the biological sciences. In the past decade, we have witnessed major advances made possible by biotechnology in areas such as rapid, low-cost DNA sequencing, metabolic engineering, and high-throughput screening. The manufacturing of chemicals using biological synthesis and engineering could expand even faster. A proactive strategy - implemented through the development of a technical roadmap similar to those that enabled sustained growth in the semiconductor industry and our explorations of space - is needed if we are to realize the widespread benefits of accelerating the industrialization of biology. Industrialization of Biology presents such a roadmap to achieve key technical milestones for chemical manufacturing through biological routes. This report examines the technical, economic, and societal factors that limit the adoption of bioprocessing in the chemical industry today and which, if surmounted, would markedly accelerate the advanced manufacturing of chemicals via industrial biotechnology. Working at the interface of synthetic chemistry, metabolic engineering, molecular biology, and synthetic biology, Industrialization of Biology identifies key technical goals for next-generation chemical manufacturing, then identifies the gaps in knowledge, tools, techniques, and systems required to meet those goals, and targets and timelines for achieving them. This report also considers the skills necessary to accomplish the roadmap goals, and what training opportunities are required to produce the cadre of skilled scientists and engineers needed."--$cPublisher's description. 606 $aBiotechnology industries 606 $aChemical industry$xTechnological innovations 606 $aChemical industry$zUnited States 606 $aBiotechnology industries$zUnited States 607 $aUnited States$2fast 615 0$aBiotechnology industries. 615 0$aChemical industry$xTechnological innovations. 615 0$aChemical industry 615 0$aBiotechnology industries 676 $a660.63 712 02$aNational Research Council (U.S.).$bCommittee on Industrialization of Biology: A Roadmap to Accelerate the Advanced Manufacturing of Chemicals, 712 02$aNational Research Council (U.S.).$bBoard on Chemical Sciences and Technology, 712 02$aNational Research Council (U.S.).$bDivision on Earth and Life Studies, 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910818706403321 996 $aIndustrialization of biology$94118628 997 $aUNINA