LEADER 04801oam 2200601Ia 450 001 9910818385103321 005 20231102195644.0 010 $a1-281-20373-4 010 $a9786611203733 010 $a0-470-18067-6 010 $a0-470-18066-8 035 $a(CKB)1000000000376506 035 $a(EBL)331557 035 $a(OCoLC)476130980 035 $a(SSID)ssj0000216053 035 $a(PQKBManifestationID)11199418 035 $a(PQKBTitleCode)TC0000216053 035 $a(PQKBWorkID)10195431 035 $a(PQKB)10394543 035 $a(OCoLC)608622392 035 $a(MiAaPQ)EBC331557 035 $a(EXLCZ)991000000000376506 100 $a19841022d2008 uy 0 101 0 $aeng 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 04$aThe organic chemistry of drug synthesis$hVolume 7 /$fDaniel Lednicer 210 1$aHoboken, N.J. :$cJohn Wiley & Sons,$d2008. 215 $a1 online resource (xiii, 272 pages) $cillustrations 225 0 $aOrganic chemistry of drug synthesis 300 $a"Wiley-Interscience." 311 0 $a0-470-10750-2 327 $aTHE ORGANIC CHEMISTRY OF DRUG SYNTHESIS; CONTENTS; Preface; 1 OPEN-CHAIN COMPOUNDS; 1. Peptidomimetic Compounds; A. Antiviral Protease Inhibitors; 1. Human Immunodeficiency Virus; 2. Human Rhinovirus; 2. Miscellaneous Peptidomimetic Compounds; References; 2 ALICYCLIC COMPOUNDS; 1. Monocyclic Compounds; A. Prostaglandins; B. Antiviral Agents; C. Miscellaneous Monocyclic Compounds; 2. Polycyclic Compounds: Steroids; A. 19-Nor Steroids; B. Corticosteroid Related Compounds; 3. Polycyclic Compounds; References; 3 MONOCYCLIC AROMATIC COMPOUNDS; 1. Arylcarbonyl Derivatives; 2. Biphenyls 327 $a3. Compounds Related to Aniline 4. Compounds Related to Arylsulfonic Acids; 5. Diarylmethanes; 6. Miscellaneous Monocyclic Aromatic Compounds; References; 4 CARBOCYCLIC COMPOUNDS FUSED TO A BENZENE RING; 1. Indenes; 2. Naphthalenes; 3. Tetrahydronaphthalenes; 4. Other benzofused carbocyclic compounds; References; 5 FIVE-MEMBERED HETEROCYCLES; 1. Compounds with One Heteroatom; 2. Compounds with Two Heteroatoms; A. Oxazole and Isoxazoles; B. Imidazoles and a Pyrrazole; C. Thiazoles; D. Triazoles; E. Tetrazoles; References; 6 SIX-MEMBERED HETEROCYCLES; 1. Compounds with One Heteroatom 327 $aA. PyridinesB. Reduced Pyridines; C. Miscellaneous; 2. Compounds with Two Heteroatoms; A. Pyrimidines; B. Miscellaneous Six-Membered Heterocycles; References; 7 FIVE-MEMBERED HETEROCYCLES FUSED TO ONE BENZENE RING; 1. Compounds with One Heteroatom; A. Benzofurans; B. Indoles; C. Indolones; D. Miscellaneous Compounds with One Heteroatom; 2. Five-Membered Rings with Two Heterocyclic Atoms; A. Benzimidazoles; B. Miscellaneous Compounds; References; 8 SIX-MEMBERED HETEROCYCLES FUSED TO ONE BENZENE RING; 1. Compounds with One Heteroatom; A. Benzopyrans; B. Quinolines and Their Derivatives 327 $aC. Quinolone Antibacterial Agents 2. Compounds with Two Heteroatoms; A. Benzoxazines; B. Quinazolines; C. Miscellaneous Benzo-Fused Heterocycles; References; 9 BICYCLIC FUSED HETEROCYCLES; 1. Compounds with Five-Membered Rings Fused to Six-Membered Rings; A. Compounds with Two Heteroatoms; B. Compounds with Three Heteroatoms; C. Compounds with Four Heteroatoms; 2. Compounds with Two Fused Six-Membered Rings; 3. Miscellaneous Compounds with Two Fused Heterocyclic Rings: Beta Lactams; References; 10 POLYCYCLIC FUSED HETEROCYCLES; 1. Compounds with Three Fused Rings; 2. Compounds with Four Fused Rings 3. Compounds with Five or More Fused Rings: Camptothecins; References; Subject Index; Cross Index of Biological Activity; Cumulative Index 330 $aThe classic reference on the synthesis of medicinal agents --now completely updated The seventh volume in the definitive series that provides a quick yet thorough overview of the synthetic routes used to access specific classesof therapeutic agents, this volume covers approximately 220 new non-proprietary drug entities introduced since the publication of Volume 6.Many of these compounds represent novel structural types firstidentified by sophisticated new cell-based assays. Specifically, a significant number of new antineoplastic and antiviral agents are covered. 410 0$aOrganic Chemistry Series of Drug Synthesis;$v7 606 $aPharmaceutical chemistry 606 $aOrganic compounds$xSynthesis 615 0$aPharmaceutical chemistry. 615 0$aOrganic compounds$xSynthesis. 676 $a547.2 676 $a615/.19 701 $aLednicer$b Daniel$f1929-$091622 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910818385103321 996 $aThe organic chemistry of drug synthesis$93946923 997 $aUNINA