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100   $a20121108d2013      uy         0
101 0 $aeng
135   $aur|||||||||||
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 00$aPaternal influences on human reproductive success /$f[edited by] Douglas T. Carrell
205   $a1st ed.
210   $aCambridge $cCambridge University Press$d2013
215   $a1 online resource (xi, 195 pages) $cdigital, PDF file(s)
300   $aTitle from publisher's bibliographic system (viewed on 05 Oct 2015).
311   $a1-107-02448-X 
320   $aIncludes bibliographical references and index.
327   $asection 1. Advances in understanding the male gamete -- section 2. The influence of aging and environmental factors on male reproductive success -- section 3. Clinical laboratory concepts and considerations.
330   $aHistorically, sperm have been seen as simply a mechanism of transferring a haploid set of chromosomes to the oocyte. However, data from assisted reproduction therapies (ART) have demonstrated that in many couples the sperm appears to be responsible for abnormal embryogenesis. Recent advances in genetic and epigenetic techniques have identified key mechanisms by which the sperm, and the DNA carried by the sperm, can affect early embryonic development. Paternal Influences on Human Reproductive Success examines the genetic and epigenetic influences on embryogenesis, as well as practical clinical factors related to the male contribution to reproductive success. It also provides 'cutting edge' data and analysis of recent evaluations of the role of advanced paternal age, environmental influences and lifestyle factors on male reproductive fitness, making this an invaluable text for physicians treating patients for infertility, recurrent pregnancy loss, and developmental anomalies, as well as basic scientists studying embryogenesis and spermatogenesis.
606   $aInfertility, Male$xSocial aspects
615  0$aInfertility, Male$xSocial aspects.
676   $a616.6/921
701   $aCarrell$b Douglas T$01759255
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910818181703321
996   $aPaternal influences on human reproductive success$94197659
997   $aUNINA