LEADER 05486nam 2200697 450 001 9910817991203321 005 20200520144314.0 010 $a0-85709-850-0 010 $a0-85709-844-6 035 $a(CKB)3710000000453347 035 $a(EBL)2111104 035 $a(SSID)ssj0001568588 035 $a(PQKBManifestationID)16217354 035 $a(PQKBTitleCode)TC0001568588 035 $a(PQKBWorkID)14835670 035 $a(PQKB)11493560 035 $a(Au-PeEL)EBL2111104 035 $a(CaPaEBR)ebr11082358 035 $a(CaONFJC)MIL822636 035 $a(OCoLC)915311708 035 $a(MiAaPQ)EBC2111104 035 $a(PPN)192177354 035 $a(EXLCZ)993710000000453347 100 $a20150808h20152015 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aNanotechnology-enhanced orthopedic materials $efabrications, applications and future trends /$fLei Yang 210 1$aAmsterdam, [Netherlands] :$cWoodhead Publishing,$d2015. 210 4$dİ2015 215 $a1 online resource (218 p.) 225 1 $aWoodhead Publishing Series in Biomaterials ;$vNumber 102 300 $aDescription based upon print version of record. 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $aFront Cover; Nanotechnology-Enhanced Orthopedic Materials: Fabrications, Applications and Future Trends; Copyright; Contents; Woodhead Publishing Series in Biomaterials; Foreword; Acknowledgments; Chapter 1: Fundamentals of nanotechnology and orthopedic materials; 1.1 Introduction: nanotechnology and nanomaterials; 1.2 Fundamentals of fabrication and modification of nanomaterials; 1.2.1 Fabrication strategies: top-down and bottom-up; 1.2.1.1 Top-down strategy; Patterning techniques; Additive techniques; Subtractive techniques; Comminution (break-down) techniques 327 $a1.2.1.2 Bottom-up strategyColloidal synthesis; Unguided self-assembly; Template-assisted self-assembly; Phase separation approaches; 1.2.1.3 Combination of top-down and bottom-up strategies; 1.2.2 Modification of nanomaterials; 1.2.2.1 Coating deposition; 1.2.2.2 Discharge and plasma treatments; 1.2.2.3 Molecular grafting; 1.2.2.4 Enzymatic modification; 1.3 Interactions between musculoskeletal tissue and biomaterial; 1.3.1 Biological responses to biomaterials; 1.3.2 Nanomaterial properties affecting biological responses; 1.3.2.1 Size and surface area 327 $a1.3.2.2 Topography and roughness1.3.2.3 Surface chemistry; 1.3.2.4 Surface wettability and surface energy; 1.3.2.5 Other nanomaterial properties; 1.4 Summary; References; Chapter 2: Nanotechnology-enhanced metals and alloys for orthopedic implants; 2.1 Fabrication techniques of nanostructured metals and alloys; 2.1.1 Vapor condensation or deposition; 2.1.2 High-energy ball milling; 2.1.3 Wet-chemical synthesis; 2.1.4 Severe plastic deformation; 2.1.5 Anodization; 2.1.6 Other fabrication methods 327 $a2.2 Nanostructured metals for better orthopedic implants with improved biological functions2.2.1 Ti-based biomaterials; 2.2.2 Nanophase CoCrMo; 2.2.3 Nanostructured selenium (Se) for inhibiting cancer cell; 2.3 Nanotechnology-enabled functionality in metallic implants; 2.3.1 Nanostructured metals for preventing infection; 2.3.2 Drug delivery via nanostructured implants; 2.3.3 Metallic nanoparticles for sensing and detection; 2.4 Nanostructured metallic implants with superior mechanical properties; 2.5 Commercialization status of nanostructured metallic implants; 2.6 Summary 327 $aReferencesChapter 3: Orthopedic nanoceramics; 3.1 Fabrication of nanoceramics; 3.1.1 Synthesis of ceramic nanoparticles; 3.1.2 Fabrication of ceramic nanocoatings; 3.1.3 Fabrication of ceramic nanoscaffolds; 3.2 Nanoceramics for orthopedic applications; 3.2.1 Nanoparticles; 3.2.1.1 Iron oxides; 3.2.1.2 Calcium phosphates; 3.2.1.3 Other ceramic nanoparticles; 3.2.2 Nanocoatings; 3.2.2.1 Oxides; 3.2.2.2 Calcium phosphates and apatite; 3.2.3 Nanotechnology-enhanced structural ceramics; 3.2.4 Nanoscaffolds; 3.3 Commercialization status of orthopedic nanoceramics; 3.4 Summary 327 $aReferences 330 $a Nanotechnology-Enhanced Orthopedic Materials provides the latest information on the emergence and rapid development of nanotechnology and the ways it has impacted almost every aspect of biomedical engineering. This book provides readers with a comprehensive overview of the field, focusing on the fabrication and applications of these materials, presenting updated, practical, and systematic knowledge on the synthesis, processing, and modification of nanomaterials, along with the rationale and methodology of applying such materials for orthopedic purposes. Topics covered include a wide ra 410 0$aWoodhead Publishing series in biomaterials ;$vNumber 102. 606 $aOrthopedic implants 606 $aBiomedical materials 606 $aOrthopedic surgery 606 $aOrthopedics 615 0$aOrthopedic implants. 615 0$aBiomedical materials. 615 0$aOrthopedic surgery. 615 0$aOrthopedics. 676 $a610.28 700 $aYang$b Lei$0909422 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910817991203321 996 $aNanotechnology-enhanced orthopedic materials$94071712 997 $aUNINA