LEADER 04285nam 2200541 450 001 9910817720203321 005 20230808205232.0 010 $a1-119-27245-9 010 $a1-119-27375-7 010 $a1-119-27376-5 035 $a(CKB)4330000000009856 035 $a(EBL)4556823 035 $a(OCoLC)951978159 035 $a(MiAaPQ)EBC4556823 035 $a(MiAaPQ)EBC6267593 035 $a(EXLCZ)994330000000009856 100 $a20201119d2016 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $2rdacontent 182 $2rdamedia 183 $2rdacarrier 200 10$aMultiple biological sequence alignment $escoring functions, algorithms and applications /$fKen Nguyen, Xuan Guo, Yi Pan 210 1$aHoboken, New Jersey :$cJohn Wiley & Sons, Inc.,$d2016. 215 $a1 online resource (286 p.) 225 0 $aWiley series on bioinformatics: computational techniques and engineering 300 $aDescription based upon print version of record. 311 $a1-118-22904-5 320 $aIncludes bibliographical references and index. 327 $aTitle Page; Copyright; Table of Contents; Preface; Chapter 1: Introduction; 1.1 Motivation; 1.2 The Organization of this Book; 1.3 Sequence Fundamentals; Chapter 2: Protein/DNA/RNA Pairwise Sequence Alignment; 2.1 Sequence Alignment Fundamentals; 2.2 Dot-Plot Matrix; 2.3 Dynamic Programming; 2.4 Word Method; 2.5 Searching Sequence Databases; References; Chapter 3: Quantifying Sequence Alignments; 3.1 Evolution and Measuring Evolution; 3.2 Substitution Matrices and Scoring Matrices; 3.3 GAPS; 3.4 Scoring Multiple Sequence Alignments; 3.5 Circular Sum Score; 3.6 Conservation Score Schemes 327 $a3.7 Diversity Scoring Schemes3.8 Stereochemical Property Methods; 3.9 Hierarchical Expected Matching Probability Scoring Metric (HEP); Chapter 4: Sequence Clustering; 4.1 Unweighted Pair Group Method with Arithmetic Mean - UPGMA; 4.2 Neighborhood-Joining Method - NJ; 4.3 Overlapping Sequence Clustering; Chapter 5: Multiple Sequences Alignment Algorithms; 5.1 Dynamic Programming; 5.2 Progressive Alignment; 5.3 Consistency and Probabilistic MSA; 5.4 Genetic Algorithms; 5.5 New Development in Multiple Sequence Alignment Algorithms; 5.6 Test Data and Alignment Methods; 5.7 Results 327 $aChapter 6: Phylogeny in Multiple Sequence Alignments6.1 The Tree of Life; 6.2 Phylogeny Construction; 6.3 Inferring Phylogeny from Multiple Sequence Alignments; Chapter 7: Multiple Sequence Alignment on High-Performance Computing Models; 7.1 Parallel Systems; 7.2 Exiting Parallel Multiple Sequence Alignment; 7.3 Reconfigurable-Mesh Computing Models - (R-Mesh); 7.4 Pairwise Dynamic Programming Algorithms; 7.5 Progressive Multiple Sequence Alignment ON R-Mesh; Chapter 8: Sequence Analysis Services; 8.1 EMBL-EBI: European Bioinformatics Institute 327 $a8.2 NCBI: National Center for Biotechnology Information8.3 GenomeNet and Data Bank of Japan; 8.4 Other Sequence Analysis and Alignment Web Servers; 8.5 SeqAna: Multiple Sequence Alignment with Quality Ranking; 8.6 Pairwise Sequence Alignment and Other Analysis Tools; 8.7 Tool Evaluation; Chapter 9: Multiple Sequence for Next-Generation Sequences; 9.1 Introduction; 9.2 Overview of Next Generation Sequence Alignment Algorithms; Chapter 10: Multiple Sequence Alignment for Variations Detection; 10.1 Introduction; 10.2 Genetic Variants; 10.3 Variation Detection Methods Based on MSA 327 $a10.4 Evaluation Methodology10.5 Conclusion and Future Work; Chapter 11: Multiple Sequence Alignment for Structure Detection; 11.1 Introduction; 11.2 RNA Secondary Structure Prediction Based on MSA; 11.3 Protein Secondary Structure Prediction Based on MSA; 11.4 Conclusion and Future Work; References; Index; End User License Agreement 410 0$aWiley series on bioinformatics. 606 $aSequence alignment (Bioinformatics) 615 0$aSequence alignment (Bioinformatics) 676 $a572.8 700 $aNguyen$b Ken$f1975-$01647029 702 $aGuo$b Xuan$f1987- 702 $aPan$b Yi$f1960- 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910817720203321 996 $aMultiple biological sequence alignment$93994377 997 $aUNINA