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100   $a20120424d2013      uy         0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 00$aReverse genetics of RNA viruses$b[electronic resource] $eapplications and perspectives /$fedited by Anne Bridgen
205   $a1st ed.
210   $aChichester, West Sussex $cJohn Wiley & Sons$d2013
215   $a1 online resource (414 p.)
300   $aDescription based upon print version of record.
311   $a0-470-97965-8 
320   $aIncludes bibliographical references and index.
327   $aDefinitions of reverse genetics, +ve, -ve, sense and doubled stranded (DS) RNA viruses / Anne Bridgen -- Coronavirus reverse genetics / Paul Britton -- Hepatitis C and use of reverse genetics in drug design / Natalia Frias Staheli -- Norovirus reverse genetics / Ian Goodfellow -- Rhabdovirus reverse genetics / Klaus Conzelmann -- Modification of measles virus and application to pathogenesis studies / Paul Duprex -- Bunyavirus reverse genetics and application to interaction with host cells / Richard Elliott -- Influenza A virus vaccines / Wendy Barclay -- Bluetongue virus reverse genetics / Mark Boyce -- Reovirus reverse genetics / Rob Hoeben -- Reverse genetics and quasispecies / Marco Vignuzzi -- Summary and perspectives / Anne Bridgen.
330   $a Reverse genetics, the genetic manipulation of RNA viruses to create a wild-type or modified virus, has led to important advances in our understanding of viral gene function and interaction with host cells. Since many severe viral human and animal pathogens are RNA viruses, including those responsible for polio, measles, rotaviral diarrhoea  and influenza infections, it is also an extremely powerful technique with important potential application for the prevention and control of a range of human and animal viral diseases.  Reverse Genetics of RNA Viruses provides a comprehensive 
606   $aRNA viruses
606   $aReverse genetics
606   $aViral proteins
606   $aViral vaccines
615  0$aRNA viruses.
615  0$aReverse genetics.
615  0$aViral proteins.
615  0$aViral vaccines.
676   $a579.2/5
701   $aBridgen$b Anne$f1961-$01634529
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910817603703321
996   $aReverse genetics of RNA viruses$93974780
997   $aUNINA