LEADER 05396nam 2200673 a 450 001 9910817439903321 005 20200520144314.0 010 $a1-283-71647-X 010 $a0-12-397762-2 035 $a(CKB)2670000000268689 035 $a(EBL)1061963 035 $a(OCoLC)818819767 035 $a(SSID)ssj0000789787 035 $a(PQKBManifestationID)12398964 035 $a(PQKBTitleCode)TC0000789787 035 $a(PQKBWorkID)10733309 035 $a(PQKB)10937033 035 $a(Au-PeEL)EBL1061963 035 $a(CaPaEBR)ebr10619218 035 $a(CaONFJC)MIL402897 035 $a(MiAaPQ)EBC1061963 035 $a(PPN)176323384 035 $a(EXLCZ)992670000000268689 100 $a20121115d2013 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aBioactive food as dietary interventions for diabetes /$fedited by Ronald Ross Watson and Victor R. Preedy 205 $a1st ed. 210 $aBoston $cElsevier$d2013 215 $a1 online resource (659 p.) 225 0 $aBioactive foods in chronic disease states 300 $aDescription based upon print version of record. 311 $a0-12-397153-5 320 $aIncludes bibliographical references and index. 327 $aFront Cover; Bioactive Food as Dietary Interventions for Diabetes; Copyright; Contents; Preface: Diabetes Food; Contributors; Chapter 1: Role of Oxidative Stress in the Pathogenesis of Insulin Resistance and Type 2 Diabetes; 1. Introduction; 2. Systemic Glucose Homeostasis is a Multiorgan Process; 3. Glucose Dysregulation: The Pathogenesis of Insulin Resistance; 4. Origins of Oxidative Stress in Various Cell Types; 4.1. Renin-Angiotensin System and NADPH Oxidase; 4.2. Nutrient Excess and Mitochondrial Overactivity; 4.3. Hyperglycemia; 4.4. Dyslipidemia: Role of Excess FFAs 327 $a4.5. Endoplasmic Reticulum Stress4.6. Additional Role of Nitrosative Stress; 5. Mechanisms of Oxidative Stress-Associated Insulin Resistance; 5.1. Oxidative Stress and Defects in Insulin Signaling: Skeletal Muscle and Liver; 5.2. Oxidative Stress and Defects in Insulin Secretion: Pancreatic Beta-Cells; 5.3. Oxidative Stress and Defects in Vascular Function; 6. Utility of Select Antioxidants as Interventions in Oxidative Stress-Associated Insulin Resistance; 6.1. General Concepts of Antioxidant Properties; 6.2. ALA and Its Effects on Glucoregulation; 7. Conclusion and Perspectives 327 $aAcknowledgmentsReferences; Relevant Websites; Chapter 2: Diabetes and the Role of Dietary Supplements; 1. Introduction; 2. Alpha-Lipoic Acid; 3. Omega-3 Oils; 4. Chromium; 5. Gymnemma Sylvestre; 6. Fenugreek; 7. Vitamin D; 8. Conclusion; Glossary; References; Chapter 3: Government Regulation of Dietary Supplements and Foods: Role in Diabetes; 1. Introduction; 2. Nongovernmental Recommendations for Diabetics; 3. NHPs for Diabetics; 4. Food Label Information and Nutrition - Health Claims; 5. Nutrition Recommendations for Diabetics; 6. Conclusions; References 327 $aChapter 4: Diabetes as an Immune Dysfunction Syndrome1. Diagnostic Laboratory Testing; 1.1. First-Line Assessments; 1.1.1. Glucose and insulin levels; 1.1.2. HbA1c; 1.2. Additional Testing; 1.2.1. C-octanoic acid breath test; 1.2.2. C-peptide; 1.2.3. C-reactive protein (hsCRP); 1.2.4. Cortisol and DHEA; 1.2.5. Lymphocyte Response Assay (LRA) tests; 1.2.6. Fibrinogen; 1.2.7. Homocysteine; 1.2.8. Insulin-like growth factor binding protein-1; 1.2.9. Intestinal hyperpermeability test; 1.2.10. Iron and ferritin; 1.2.11. Oxidized LDL (oxLDL); 1.2.12. Metabolic acidosis risk 327 $a1.2.13. Sleep survey or evaluation2. Key Clinical Issues; 2.1. Energy Metabolism; 2.1.1. Glucose; 2.1.2. Fructose; 2.1.3. Protein metabolism in diabetes; 2.1.4. Fat metabolism; 2.2. Autonomic Neuropathy; 2.3. Immune Dysregulation and Increased Permeability; 2.4. Maldigestion; 2.4.1. Reflux; 2.4.2. Dyspepsia; 2.4.3. Dysbiosis; 2.4.4. Malabsorption; 2.4.5. Delayed gastric emptying; 2.5. Autacoids: Profound Biochemical Effects; 3. Diagnoses and Comorbidities; 3.1. Prevalent Comorbidities; 3.1.1. Vascular sequella and neurodegeneration; 3.1.2. Hyperlipidemia and hypertension 327 $a3.1.3. Kidney disease 330 $a The role of diet in the prevention, control and treatment of diabetes continues to provide significant opportunity for non-pharmaceutical interventions for many of the over 20 million people who live with this disease. Looking beyond traditional dietary controls may lead to more effective, cost efficient, and flexible options for many patients. Bioactive Food as Dietary Interventions for Diabetes is the only available scientific resource focused on exploring the latest advances in bioactive food research, and the potential benefit of bioactive food choice on the diabetic condi 606 $aDiabetes$xNutritional aspects 606 $aBioactive compounds 615 0$aDiabetes$xNutritional aspects. 615 0$aBioactive compounds. 676 $a613.2 676 $a616.4620654 701 $aWatson$b Ronald R$g(Ronald Ross)$0872276 701 $aPreedy$b Victor R$0858423 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910817439903321 996 $aBioactive food as dietary interventions for diabetes$94075418 997 $aUNINA