LEADER 04828nam 22006134a 450 001 9910817426603321 005 20240417001303.0 010 $a0-309-17171-7 010 $a1-280-18534-1 010 $a9786610185344 010 $a0-309-56970-2 035 $a(CKB)110986584753150 035 $a(EBL)3377375 035 $a(SSID)ssj0000284928 035 $a(PQKBManifestationID)11912606 035 $a(PQKBTitleCode)TC0000284928 035 $a(PQKBWorkID)10261691 035 $a(PQKB)10380620 035 $a(MiAaPQ)EBC3377375 035 $a(Au-PeEL)EBL3377375 035 $a(CaPaEBR)ebr10071402 035 $a(CaONFJC)MIL18534 035 $a(OCoLC)923270163 035 $a(EXLCZ)99110986584753150 100 $a20000829d2000 ua 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aToxicological effects of methylmercury /$fCommittee on the Toxicological Effects of Methylmercury, Board on Environmental Studies and Toxicology, Commission on Life Sciences, National Research Council 205 $a1st ed. 210 $aWashington, DC $cNational Academy Press$dc2000 215 $a1 online resource (368 p.) 300 $aDescription based upon print version of record. 311 $a0-309-07140-2 320 $aIncludes bibliographical references. 327 $a""Toxicological Effects of Methylmercury""; ""Copyright""; ""PREFACE""; ""Contents""; ""EXECUTIVE SUMMARY""; ""THE CHARGE TO THE COMMITTEE""; ""THE COMMITTEE'S APPROACH TO ITS CHARGE""; ""THE COMMITTEE'S EVALUATION""; ""Health Effects of Methylmercury""; ""Determination of the Critical Study for the RfD""; ""Estimation of Dose and Biological Variability""; ""Modeling the Dose-Response Relationships""; ""Public Health Implications""; ""RESEARCH NEEDS""; ""RECOMMENDATIONS""; ""1 INTRODUCTION""; ""SOURCES OF HG""; ""FATE AND TRANSPORT""; ""HEALTH EFFECTS""; ""EXPOSURE EVENTS AND STUDIES"" 327 $a""SUMMARY OF RISK ASSESSMENTS FOR MEHG""""SCIENTIFIC CONTROVERSIES AND SOURCES OF UNCERTAINTY""; ""ORGANIZATION OF THE REPORT""; ""REFERENCES""; ""2 CHEMISTRY, EXPOSURE, TOXICOKINETICS, AND TOXICODYNAMICS ""; ""PHYSICAL AND CHEMICAL PROPERTIES""; ""METHODS OF CHEMICAL ANALYSIS""; ""EXPOSURES TO MEHG IN THE U.S. POPULATION""; ""TOXICOKINETICS""; ""Absorption and Distribution""; ""Methylmercury""; ""Dimethylmercury""; ""Elemental Mercury""; ""Inorganic Mercury""; ""Biotransformation""; ""Excretion""; ""MOBILIZATION OF BODY HG""; ""CHEMICAL FORMS OF HG IN TOXICITY"" 327 $a""TOXIC EFFECTS AND TARGET ORGANS""""BIOCHEMICAL MECHANISMS OF TOXICITY""; ""SUMMARY AND CONCLUSIONS""; ""RECOMMENDATIONS""; ""REFERENCES""; ""3 BIOLOGICAL VARIABILITY ""; ""AGE-RELATED SUSCEPTIBILITY""; ""GENDER DIFFERENCES""; ""GENETICS""; ""MECHANISMS OF NUTRITIONAL INFLUENCE ON MEHG HEALTH EFFECTS""; ""Dietary Interactions and Confounding""; ""Selenium""; ""Garlic""; ""Omega-3 Fatty Acids""; ""Protein""; ""Alcohol""; ""Other Foods That Might Influence Hg Uptake""; ""Vitamin E""; ""Nutrient Enhancement of Toxicity""; ""Beneficial Effects of Fish Consumption""; ""TOXICOKINETIC VARIABILITY"" 327 $a""CONCLUSIONS""""RECOMMENDATIONS""; ""REFERENCES""; ""4 DOSE ESTIMATION ""; ""DIETARY ASSESSMENT""; ""BIOMARKERS OF EXPOSURE""; ""Methylmercury in Blood""; ""Methylmercury in Hair""; ""Comparison of Biomarkers of Exposure""; ""ANALYTICAL ERROR IN BIOMARKER MEASUREMENTS""; ""EXPOSURE AND DOSE ASSESSMENT IN THE SEYCHELLES, FAROE ISLANDS, AND NEW ZEALAND STUDIES""; ""SUMMARY AND CONCLUSIONS""; ""RECOMMENDATIONS""; ""REFERENCES""; ""5 HEALTH EFFECTS OF METHYLMERCURY ""; ""CARCINOGENICITY""; ""Human Studies""; ""Animal Studies""; ""GENOTOXICITY""; ""Human Studies""; ""Animal Studies"" 327 $a""In Vitro Studies""""IMMUNOTOXICITY""; ""Human Studies""; ""Animal Studies""; ""Effects on the Adult Immune System""; ""Effects on the Developing Immune System""; ""In Vitro Studies""; ""Autoimmune Response""; ""Human Studies""; ""Animal Studies""; ""REPRODUCTIVE EFFECTS""; ""Human Studies""; ""Animal Studies""; ""RENAL TOXICITY""; ""Human Studies""; ""Animal Studies""; ""CARDIOVASCULAR EFFECTS""; ""Human Studies""; ""Animal Studies""; ""HEMATOLOGICAL EFFECTS""; ""DEVELOPING CENTRAL-NERVOUS-SYSTEM TOXICITY""; ""Human Studies""; ""High-Dose Poisonings""; ""Poisoning Episode in Japan"" 327 $a""Poisoning Episode in Iraq"" 606 $aMethylmercury$xToxicology 615 0$aMethylmercury$xToxicology. 676 $a615.9/25663 712 02$aNational Research Council (U.S.).$bCommittee on the Toxicological Effects of Methylmercury. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910817426603321 996 $aToxicological effects of methylmercury$94024091 997 $aUNINA