LEADER 06069nam 2200841I 450 001 9910817010203321 005 20240924135614.0 010 $a9783527639328 010 $a1-283-60404-3 010 $a9786613916495 010 $a3-527-33214-6 010 $a3-527-63934-9 010 $a3-527-63932-2 035 $a(CKB)3280000000000389 035 $a(EBL)1023281 035 $a(OCoLC)815389167 035 $a(SSID)ssj0000622250 035 $a(PQKBManifestationID)11388574 035 $a(PQKBTitleCode)TC0000622250 035 $a(PQKBWorkID)10655010 035 $a(PQKB)10378417 035 $a(MiAaPQ)EBC1023281 035 $a(Au-PeEL)EBL1023281 035 $a(CaPaEBR)ebr10602115 035 $a(CaONFJC)MIL391649 035 $a(PPN)224947826 035 $a(EXLCZ)993280000000000389 100 $a20110616d2011 uy 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aBoronic acids$hVolume 2$iPreparation and applications in organic synthesis, medicine and materials /$fedited by Dennis G. Hall ; with a foreword by Akira Suszuki 205 $aSecond completely revised edition 210 1$aWeinheim :$cWiley-VCH,$d[2011]. 215 $a1 online resource (729 pages) 300 $aDescription based upon print version of record. 311 1 $a9783527325986 311 1 $a3-527-32598-0 320 $aIncludes bibliographical references and index. 327 $aBoronic Acids: Preparation and Applications in Organic Synthesis, Medicine and Materials; Foreword; Contents to Volume 1; Contents to Volume 2; Preface; List of Contributors; 1 Structure, Properties, and Preparation of Boronic Acid Derivatives: Overview of Their Reactions and Applications; 1.1 Introduction and Historical Background; 1.2 Structure and Properties of Boronic Acid Derivatives; 1.2.1 General Types and Nomenclature of Boronic Acid Derivatives; 1.2.2 Boronic Acids; 1.2.2.1 Structure and Bonding; 1.2.2.2 Physical Properties and Handling; 1.2.2.3 Safety Considerations 327 $a1.2.2.4 Acidic Character1.2.2.5 Chemical Stability; 1.2.3 Boronic Acid Derivatives; 1.2.3.1 Boroxines (Cyclic Anhydrides); 1.2.3.2 Boronic Esters; 1.2.3.3 Acyloxy- and Diacyloxyboronates; 1.2.3.4 Dialkoxyboranes and Other Heterocyclic Boranes; 1.2.3.5 Diboronyl Esters; 1.2.3.6 Azaborolidines and Other Boron-Nitrogen Heterocycles; 1.2.3.7 Dihaloboranes and Dihydroalkylboranes; 1.2.3.8 Trifluoro- and Trihydroxyborate Salts; 1.3 Preparation of Boronic Acids and Their Esters; 1.3.1 Arylboronic Acids; 1.3.1.1 Electrophilic Trapping of Arylmetal Intermediates with Borates 327 $a1.3.1.2 Transmetalation of Aryl Silanes and Stannanes1.3.1.3 Coupling of Aryl Halides with Diboronyl Reagents; 1.3.1.4 Direct Boronation by Transition Metal-Catalyzed Aromatic C-H Functionalization; 1.3.1.5 Cycloadditions of Alkynylboronates; 1.3.1.6 Other Methods; 1.3.2 Diboronic Acids; 1.3.3 Heterocyclic Boronic Acids; 1.3.4 Alkenylboronic Acids; 1.3.4.1 Electrophilic Trapping of Alkenylmetal Intermediates with Borates; 1.3.4.2 Transmetalation Methods; 1.3.4.3 Transition Metal-Catalyzed Coupling between Alkenyl Halides/ Triflates and Diboronyl Reagents; 1.3.4.4 Hydroboration of Alkynes 327 $a1.3.4.5 Alkene Metathesis1.3.4.6 Diboronylation and Silaboration of Unsaturated Compounds; 1.3.4.7 Other Methods; 1.3.5 Alkynylboronic Acids; 1.3.6 Alkylboronic Acids; 1.3.7 Allylic Boronic Acids; 1.3.8 Chemoselective Transformations of Compounds Containing a Boronic Acid (Ester) Substituent; 1.3.8.1 Oxidative Methods; 1.3.8.2 Reductive Methods; 1.3.8.3 Generation and Reactions of a-Boronyl-Substituted Carbanions and Radicals; 1.3.8.4 Reactions of a-Haloalkylboronic Esters; 1.3.8.5 Other Transformations; 1.3.8.6 Protection of Boronic Acids for Orthogonal Transformations 327 $a1.4 Isolation and Characterization1.4.1 Recrystallization and Chromatography; 1.4.2 Solid Supports for Boronic Acid Immobilization and Purification; 1.4.2.1 Diethanolaminomethyl Polystyrene; 1.4.2.2 Other Solid-Supported Diol Resins; 1.4.3 Analytical and Spectroscopic Methods for Boronic Acid Derivatives; 1.4.3.1 Melting Points, Combustion Analysis, and HPLC; 1.4.3.2 Mass Spectrometry; 1.4.3.3 Nuclear Magnetic Resonance Spectroscopy; 1.4.3.4 Other Spectroscopic Methods; 1.5 Overview of the Reactions of Boronic Acid Derivatives; 1.5.1 Metalation and Metal-Catalyzed Protodeboronation 327 $a1.5.2 Oxidative Replacement of Boron 330 $aFollowing the huge success of the first edition, which has become THE reference source for everyone working in the field, this long-awaited, completely updated edition features almost 50% new content.The world-renowned chemist Prof Dennis Hall is joined by a select group of top authors to cover all modern aspects of boronic acid derivatives in one comprehensive handbook. The experimental procedures described make for extremely useful reading. From the reviews of the first edition: ""...deserves to be on the bookshelf of all synthetic chemists, whether in discovery or process chemistry. 606 $aĀcids orgānics$2lemac 606 $aCompostos organobōrics$2lemac 606 $aOrganic acids 606 $aOrganoboron compounds 606 $aOrganic acids$xTherapeutic use 606 $aOrganoboron compounds$xTherapeutic use 606 $aOrganic acids$xSynthesis 606 $aOrganoboron compounds$xSynthesis 615 7$aĀcids orgānics 615 7$aCompostos organobōrics 615 0$aOrganic acids. 615 0$aOrganoboron compounds. 615 0$aOrganic acids$xTherapeutic use. 615 0$aOrganoboron compounds$xTherapeutic use. 615 0$aOrganic acids$xSynthesis. 615 0$aOrganoboron compounds$xSynthesis. 676 $a547.05671 702 $aHall$b Dennis G.$f1968- 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910817010203321 996 $aBoronic acids$94244385 997 $aUNINA