LEADER 05233nam 22006014a 450 001 9910816272403321 005 20230828222103.0 010 $a1-281-18982-0 010 $a9786611189822 010 $a0-08-047207-9 035 $a(CKB)1000000000364735 035 $a(EBL)288993 035 $a(OCoLC)476043241 035 $a(SSID)ssj0000109054 035 $a(PQKBManifestationID)11132784 035 $a(PQKBTitleCode)TC0000109054 035 $a(PQKBWorkID)10044932 035 $a(PQKB)11589180 035 $a(MiAaPQ)EBC288993 035 $a(Au-PeEL)EBL288993 035 $a(CaPaEBR)ebr10169920 035 $a(EXLCZ)991000000000364735 100 $a20060413d2006 uy 0 101 0 $aeng 135 $aurcn||||||||| 181 $ctxt 182 $cc 183 $acr 200 00$aBasic neurochemistry $emolecular, cellular, and medical aspects /$feditor-in-chief, George J. Siegel ; editors, R. Wayne Albers, Scott T. Brady, Donald L. Price 205 $a7th ed. 210 $aAmsterdam ;$aBoston $cElsevier$dc2006 215 $a1 online resource (1020 p.) 300 $aDescription based upon print version of record. 311 $a0-12-088397-X 320 $aIncludes bibliographical references. 327 $aBasic Neurochemistry; Basic Neurochemistry; Contents; Section Editors; Contributors; Acknowledgments and History; Preface to the Seventh Edition; Pierre Morell, Ph.D. 1941-2003; Cellular Neurochemistry and Neural Membranes; Neurocellular Anatomy; UNDERSTANDING NEUROANATOMY IS NECESSARY TO STUDY NEUROCHEMISTRY; CHARACTERISTICS OF THE NEURON; CHARACTERISTICS OF NEUROGLIA; ACKNOWLEDGMENTS; REFERENCES; Cell Membrane Structures and Functions; PHOSPHOLIPID BILAYERS; MEMBRANE PROTEINS; BIOLOGICAL MEMBRANES; REFERENCES; Lipids; PROPERTIES OF BRAIN LIPIDS; COMPLEX LIPIDS; ANALYSIS OF BRAIN LIPIDS 327 $aBRAIN LIPID BIOSYNTHESISGENES FOR LIPID-SYNTHESIZING ENZYMES; LIPIDS IN THE CELLULAR MILIEU; GENERAL REFERENCES; REFERENCES; Myelin Formation, Structure and Biochemistry; THE MYELIN SHEATH; CHARACTERISTIC COMPOSITION OF MYELIN; DEVELOPMENTAL AND METABOLIC ASPECTS OF MYELIN; ACKNOWLEDGMENTS; REFERENCES; Membrane Transport; INTRODUCTION; PRIMARY ION TRANSPORTERS; Ca2+ PUMPS; V0V1- PROTON PUMPS; ATP-BINDING CASSETTES; SECONDARY ACTIVE TRANSPORT; PHYSIOLOGICAL ASPECTS OF THE NEUROTRANSMITTER TRANSPORTERS; CATION ANTIPORTERS; FACILITATORS; REFERENCES; Electrical Excitability and Ion Channels 327 $aMEMBRANE POTENTIALS AND ELECTRICAL SIGNALS IN EXCITABLE CELLS ACTION POTENTIALS IN ELECTRICALLY EXCITABLE CELLS; FUNCTIONAL PROPERTIES OF VOLTAGE- GATED ION CHANNELS; THE VOLTAGE-GATED ION CHANNEL SUPER FAMILY; THE MOLECULAR BASIS FOR ION CHANNEL FUNCTION; ION CHANNEL DIVERSITY; ACKNOWLEDGMENTS; REFERENCES; Cell Adhesion Molecules; OVERVIEW; THE IMMUNOGLOBULIN GENE SUPER FAMILY; THE CADHERIN FAMILY; CELL ADHESION MOLECULES AND AXONAL OUTGROWTH; CELL ADHESION MOLECULES IN MYELINATION; SUMMARY; REFERENCES; The Cytoskeleton of Neurons and Glia; MOLECULAR COMPONENTS OF THE NEURONAL CYTOSKELETON 327 $aULTRASTRUCTURE AND MOLECULAR ORGANIZATION OF NEURONS AND GLIACYTOSKELETAL STRUCTURES IN THE NEURON HAVE COMPLEMENTARY DISTRIBUTIONS AND FUNCTIONS; CONCLUSIONS; REFERENCES; Intracellular Trafficking; GENERAL MECHANISMS OF INTRACELLULAR MEMBRANE TRAFFICKING IN MAMMALIAN CELLS INCLUDE BOTH UNIVERSAL AND HIGHLY SPECIALIZED PROCESSES; FUNDAMENTALS OF MEMBRANE TRAFFICKING ARE BASED ON A SET OF COMMON PRINCIPLES; THE BIOSYNTHETIC SECRETORY PATHWAY INCLUDES SYNTHETIC, PROCESSING, TARGETING AND SECRETORY STEPS; THE ENDOCYTIC PATHWAY PLAYS MULTIPLE ROLES IN CELLS OF THE NERVOUS SYSTEM 327 $aSYNAPTIC VESICLE TRAFFICKING IS A SPECIALIZED FORM OF REGULATED SECRETION AND RECYCLING OPTIMIZED FOR SPEED AND EFFICIENCY ACKNOWLEDGMENTS; REFERENCES; Intercellular Signaling; Synaptic Transmission and Cellular Signaling: An Overview; SYNAPTIC TRANSMISSION; CELLULAR SIGNALING MECHANISMS; ACKNOWLEDGMENTS; REFERENCES; Acetylcholine; CHEMISTRY OF ACETYLCHOLINE; ORGANIZATION OF THE CHOLINERGIC NERVOUS SYSTEM; FUNCTIONAL ASPECTS OF CHOLINERGIC NEUROTRANSMISSION; SYNTHESIS, STORAGE AND RELEASE OF ACETYLCHOLINE; ACETYLCHOLINESTERASE AND THE TERMINATION OF ACETYLCHOLINE ACTION; NICOTINIC RECEPTORS 327 $aMUSCARINIC RECEPTORS 330 $aBasic Neurochemistry: Molecular, Cellular and Medical Aspects, the outstanding and comprehensive classic text on neurochemistry, is now newly updated and revised in its Seventh Edition. This well-established text has been accepted worldwide as a resource for postgraduate trainees and teachers in neurology, psychiatry, and basic neuroscience, as well as for graduate and postgraduate students and instructors in the neurosciences. It is an excellent source of current information on basic biochemical processes in brain function and disease for qualifying examinations and continuing medical 606 $aNeurochemistry 615 0$aNeurochemistry. 676 $a612.8/042 701 $aSiegel$b George J$01700383 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910816272403321 996 $aBasic neurochemistry$94083342 997 $aUNINA