LEADER 02879nam 2200541 450 001 9910815883603321 005 20231025162411.0 010 $a1-118-87493-5 010 $a1-118-87492-7 010 $a1-118-87490-0 035 $a(CKB)4330000000007355 035 $a(MiAaPQ)EBC5405939 035 $a(NjHacI)994330000000007355 035 $a(BIP)061473171 035 $a(EXLCZ)994330000000007355 100 $a20180620d2018 uy 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aSample sizes for clinical, laboratory and epidemiology studies /$fDavid Machin, [and three others] 205 $aFourth edition. 210 1$aHoboken, New Jersey :$cWiley,$d[2018] 215 $a1 online resource (409 pages) 225 0 $aTHEi Wiley ebooks. 311 $a1-118-87494-3 320 $aIncludes bibliographical references and index. 327 $aRanking the Multiple Endpoints2.5 Repeated Significance Tests; Bonferroni Correction; 2.6 Epidemiological Studies; 2.7 The Protocol and Publication; 2.8 Ethical Issues and Sample Size; References; Chapter 3 Binary Outcomes; 3.1 Introduction; 3.2 Comparing Proportions; Effect Size; Analysis; ?2 Test; Fisher's Exact Test; 3.3 One Proportion Known; ?2 Test; 3.4 Bibliography; 3.5 Examples and Use of the Tables; Table 3.1 and Equations 3.2 and 3.3; Table 3.1 and Equations 3.2, 3.3, 3.4 and 3.5; Equations 3.2 and 3.5; Table 3.2 and Equations 3.1, 3.2, 3.3 and 3.4; Equations 3.1, 3.3 and 3.4. 330 $a"Sample Size Tables for Clinical Studies provides the statistical tools - equations, formulae and numerical tables - statisticians and researchers need to design and plan valid clinical studies and to accurately analyse publishable results. It explains the sample size considerations that are important when designing and planning any type of clinical study. It clearly outlines the methodologies employed, within the context of clinical studies and trials, and provides relevant practical examples. Each chapter provides and explains sets of sample size tables. They also include Bibliography and References sections directed towards further guidance on the principles discussed and more detailed explanations"--Provided by publisher. 606 $aClinical trials 610 $aResearch 610 $aStatistics 610 $aReference 610 $aMathematics 615 0$aClinical trials. 676 $a615.5072/4 700 $aMachin$b David$f1939-$0520765 702 $aCampbell$b Michael J.$f1950- 702 $aTan$b Say Beng 702 $aTan$b Sze Huey 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910815883603321 996 $aSample sizes for clinical, laboratory and epidemiology studies$93993460 997 $aUNINA