LEADER 04382nam 2200637 450 001 9910815581603321 005 20230807193029.0 010 $a0-19-100401-4 010 $a0-19-176941-X 010 $a0-19-100400-6 035 $a(CKB)3710000000470379 035 $a(EBL)2033523 035 $a(OCoLC)911191048 035 $a(SSID)ssj0001546310 035 $a(PQKBManifestationID)16134634 035 $a(PQKBTitleCode)TC0001546310 035 $a(PQKBWorkID)14792416 035 $a(PQKB)11509996 035 $a(MiAaPQ)EBC2033523 035 $a(StDuBDS)EDZ0001480147 035 $a(MiAaPQ)EBC5891125 035 $a(Au-PeEL)EBL2033523 035 $a(CaPaEBR)ebr11199724 035 $a(EXLCZ)993710000000470379 100 $a20170111h20152015 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aAntimicrobial chemotherapy /$fProfessor Peter Davey [and three others] 205 $aSeventh edition. 210 1$aOxford, [England] :$cOxford University Press,$d2015. 210 4$dİ2015 215 $a1 online resource (431 p.) 300 $aDescription based upon print version of record. 311 $a0-19-968977-6 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $aCover; Preface; Contents; List of Abbreviations; Part 1 General properties of antimicrobial agents; 1 Mechanisms of action and resistance to modern antibacterials, with a history of their development; 2 Inhibitors of bacterial cell wall synthesis; 3 Inhibitors of bacterial protein synthesis; 4 Synthetic antibacterial agents and miscellaneous antibiotics; 5 Antiviral agents; 6 Antiretroviral agents; 7 Drugs used in the treatment of viral hepatitis; 8 Antifungal agents; 9 Antiprotozoal and anthelminthic agents; Part 2 Resistance to antimicrobial agents; 10 The problem of resistance 327 $a11 The genetics and mechanisms of acquired resistancePart 3 General principles of usage of antimicrobial agents; 12 Laboratory investigations and the treatment of infection; 13 General principles of the treatment of infection; 14 Pharmacokinetic and pharmacodynamic principles; 15 Prescribing in special groups: effects of age, pregnancy, body weight, and hepatic and renal impairment; 16 OPAT: outpatient parenteral antimicrobial therapy; 17 Adverse drug reactions, and patient safety; 18 Chemoprophylaxis and immunization; 19 Guidelines, formularies, and antimicrobial policies 327 $a20 Antimicrobial stewardship, surveillance of antimicrobial consumption, and its consequencesPart 4 Therapeutic use of antimicrobial agents; 21 Respiratory tract infections; 22 Topical use of antimicrobial agents; 23 Urinary tract infections; 24 Sexually transmitted infections; 25 Gastrointestinal infections; 26 Serious bacterial bloodstream infections; 27 Bone and joint infections; 28 Infections of the central nervous system; 29 Skin and soft-tissue infections; 30 Tuberculosis and other mycobacterial diseases; 31 Infections in immunocompromised patients, including HIV/AIDS 327 $a32 Viral infections33 Management of HIV infection; 34 Treatment of chronic viral hepatitis; 35 Parasitic disease; 36 The development and marketing of antimicrobial drugs; Appendix: Recommendations for Further Reading; Index 330 $aAntimicrobial agents are essential for the treatment of life-threatening infections and for managing the burden of minor infections in the community. In addition, they play a key role in organ and bone marrow transplantation, cancer chemotherapy, artificial joint and heart valve surgery. Unlike other classes of medicines, they are vulnerable to resistance from mutations in target microorganisms, and their adverse effects may extend to other patients (increased riskof cross-infection). As a consequence, there is a constant requirement for new agents, as well as practices that ensure the continu 606 $aAnti-infective agents 606 $aCommunicable diseases$xChemotherapy 615 0$aAnti-infective agents. 615 0$aCommunicable diseases$xChemotherapy. 676 $a616.90461 702 $aDavey$b Peter G. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910815581603321 996 $aAntimicrobial chemotherapy$9745710 997 $aUNINA