LEADER 05452oam 2200625 450 001 9910815452003321 005 20170523091546.0 010 $a1-78402-348-5 010 $a0-12-397272-8 035 $a(OCoLC)853460658 035 $a(MiFhGG)GVRL6PAG 035 $a(EXLCZ)992660000000011235 100 $a20140102d2014 uy 0 101 0 $aeng 135 $aurun|---uuuua 181 $ctxt 182 $cc 183 $acr 200 10$aAvian immunology /$fedited by Karel A. Schat, Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Bernd Kaspers, Institute for Animal Physiology, University of Munich, Pete Kaiser, The Roslin Institute and R(D)SVS, University of Edinburgh 205 $a2nd ed. 210 $aSan Diego, Calif. $cAcademic Press$d2014 210 1$aAmsterdam ;$aBoston :$cElsevier :$cAcademic Press,$d2014. 215 $a1 online resource (xvi, 439 pages) $cillustrations (some color) 225 0 $aGale eBooks 300 $aPreceded by Avian immunology / edited by Fred Davison, Bernd Kaspers, Karel A. Schat. 2008. 311 $a1-299-73367-0 311 $a0-12-396965-4 320 $aIncludes bibliographical references and index. 327 $aFront Cover; Avian Immunology; Copyright Page; Contents; Acknowledgments; Foreword; List of Contributors; 1 The Importance of the Avian Immune System and its Unique Features; 1.1 Introduction; 1.2 The Contribution of Avian Lymphocytes; 1.3 The Contribution of the Bursa of Fabricius; 1.3.1 Gene Conversion and the Bursa; 1.4 The Contribution of the Chicken MHC; 1.5 The Contributions to Vaccinology; 1.5.1 Embryonic (In Ovo) Vaccination; 1.6 Conclusions; References; 2 Structure of the Avian Lymphoid System; 2.1 Introduction; 2.2 The Thymus; 2.2.1 Anatomy and Histological Organization 327 $a2.2.2 Thymic Cortex2.2.3 Thymic Medulla; 2.2.4 Thymic Cortico-Medullary Border; 2.3 The Bursa of Fabricius; 2.3.1 Anatomy and Histology; Bursal Surface Epithelium; 2.3.2 Bursal Follicle; 2.3.3 Medulla; Bursal Medullary Epithelial Cells; Bursal Secretory Dendritic Cells; Bursal Macrophages; Bursal Lymphocytes; 2.3.4 Cortex; Peripheral Lymphoid Tissue of the Bursa of Fabricius; 2.4 Germinal Center of the Peripheral Lymphoid Organs; 2.5 The Spleen; 2.5.1 Origin and Anatomy; 2.5.2 Red Pulp; 2.5.3 White Pulp; Peri-Arteriolar Lymphoid Sheath; Ellipsoids and Peri-Ellipsoid White Pulp 327 $aThe Marginal-Zone Equivalent and Antigen Handling2.6 Gut-Associated Lymphoid Tissue; 2.6.1 Follicle-Associated Epithelium or Lymphoepithelium; 2.6.2 Esophageal and Pyloric Tonsils; 2.6.3 Peyer's Patches; 2.6.4 Meckel's Diverticulum; 2.6.5 Cecal Tonsils; 2.7 Harderian and Conjunctiva-Associated Lymphoid Tissue; 2.8 Mural Lymph Node; 2.9 Ectopic Lymphatic Tissue and Pineal Gland; 2.10 Bone Marrow; 2.11 Blood; References; 3 Development of the Avian Immune System; 3.1 Introduction; 3.2 Origins and Migration Routes of Hematopoietic Cells Using Quail-Chick Complementary Chimeras 327 $a3.2.1 Looking for the Source of Hematopoeietic Cells during Development3.2.2 Macrophage Production by the Yolk Sac; 3.2.3 The Aortic Region Produces HSC; 3.3 Aortic Clusters as the Intra-Embryonic Source of Definitive Hematopoiesis; 3.3.1 Cellular and Molecular Identification of the Clusters; 3.3.2 The Para-Aortic Foci; 3.3.3 Tracing the Origins and Fates of the Aortic Clusters; 3.4 Formation of the Aorta: A Dorsal Angioblastic Lineage and a Ventral Hemangioblastic Lineage; 3.4.1 Two Endothelial Lineages Form the Vascular Network of the Embryo 327 $a3.4.2 Chimeric Origin of the Aortic Endothelial Cells3.4.3 The Allantois: Another Source of Hematopoiesis?; 3.4.4 Cellular and Molecular Identification of Allantois-Associated Hematopoiesis; 3.4.5 Hematopoietic Production by the Mammalian Allantois and the Placenta; 3.5 The Avian Thymus and T Cell Development; 3.5.1 Thymic Development; 3.5.2 Colonization of the Thymus; 3.5.3 T Cell Differentiation; 3.5.4 TCR Rearrangement; 3.5.5 T Cell Homing to the Periphery; 3.6 The Bursa of Fabricius, B-Cell Ontogeny and Immunoglobulins; 3.6.1 Formation of the Bursal Epithelial Anlage 327 $a3.6.2 Bursal Development 330 $aThe second edition of Avian Immunology provides an up-to-date overview of the current knowledge of avian immunology. From the ontogeny of the avian immune system to practical application in vaccinology, the book encompasses all aspects of innate and adaptive immunity in chickens. In addition, chapters are devoted to the immunology of other commercially important species such as turkeys and ducks, and to ecoimmunology summarizing the knowledge of immune responses in free-living birds often in relation to reproductive success. The book contains a detailed description of the avia 606 $aBirds$xImmunology 606 $aBirds$ximmunology 606 $aBird Diseases$ximmunology 606 $aImmune System 606 $aImmunity 615 0$aBirds$xImmunology. 615 12$aBirds$ximmunology. 615 22$aBird Diseases$ximmunology. 615 22$aImmune System. 615 22$aImmunity. 676 $a571.9618 702 $aSchat$b K. A$g(Karel Antoni),$f1944- 702 $aKaspers$b Bernd 702 $aKaiser$b P$g(Pete), 801 0$bMiFhGG 801 1$bMiFhGG 906 $aBOOK 912 $a9910815452003321 996 $aAvian immunology$9831232 997 $aUNINA