LEADER 04566nam 2200589 450 001 9910815140603321 005 20230421054916.0 010 $a3-11-090666-X 024 7 $a10.1515/9783110906660 035 $a(CKB)3390000000034404 035 $a(SSID)ssj0000849216 035 $a(PQKBManifestationID)11536277 035 $a(PQKBTitleCode)TC0000849216 035 $a(PQKBWorkID)10813553 035 $a(PQKB)10709800 035 $a(MiAaPQ)EBC3042712 035 $a(DE-B1597)40776 035 $a(OCoLC)979764905 035 $a(DE-B1597)9783110906660 035 $a(Au-PeEL)EBL3042712 035 $a(CaPaEBR)ebr10754877 035 $a(OCoLC)922945714 035 $a(EXLCZ)993390000000034404 100 $a19960311d1996 uy 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt 182 $cc 183 $acr 200 00$aConcepts in vaccine development /$feditor, Stefan H.E. Kaufmann 205 $aReprint 2012 210 1$aBerlin ;$aNew York :$cWalter de Gruyter,$d1996. 215 $a1 online resource (605 pages) $cillustrations 300 $aBibliographic Level Mode of Issuance: Monograph 311 0 $a3-11-178051-1 311 0 $a3-11-014815-3 320 $aIncludes bibliographical references and index. 327 $tFront matter --$tPreface --$tBicentennial of the first vaccination by Edward Jenner /$rKaufmann, Stefan H.E. --$tContents --$t1. The Need for New Vaccines --$t1.1. Vaccines as Evolutionary Tools: The Virulence-Antigen Strategy /$rEwald, Paul W. --$t1.2. Economic Perspectives on Vaccine Needs /$rAshley, Robert V. / Murray, Christopher J. L. --$t1.3. Future Immunization Strategies - Considerations from the Public Health View /$rDittmann, Sieghart --$t1.4. The New Pertussis Vaccines /$rKlein, David L. / Heilman, Carole --$t2. General Principles of Immunology --$t2.1. Basic Principles of Immunity Against Intracellular Bacteria and Protozoa /$rSzalay, Gudrun / Kaufmann, Stefan H. E. --$t2.2. Viral Immunity and Vaccine Strategies /$rWoodland, David L. / Cole, Geoffrey A. / Doherty, Peter C. --$t2.3. Broadly Reactive HLA Restricted ? Cell Epitopes and Their Implications for Vaccine Design /$rSidney, John / Kubo, Ralph T. / Wentworth, Peggy A. / Alexander, Jeff / Chesnut, Robert W. / Grey, Howard M. / Sette, Alessandro --$t2.4. Quantitative Considerations in the Design of Vaccination Strategies Against Pathogens Uniquely Susceptible to Cell-Mediated Attack /$rBretscher, Peter --$t2.5. The Impact of the Type 1 and Type 2 ? Helper Cell Concept on Novel Vaccine Design with Emphasis on Protection Against Leishmania Parasites /$rBogdan, Christian / Röllinghoff, Martin --$t3. General Principles of Vaccinology --$t3.1. Modern Adjuvants. Functional Aspects /$rMorein, Bror / Lövgren-Bengtsson, Karin / Cox, John --$t3.2. Biodegradable Microspheres as Vehicles for Antigens /$rKersten, Gideon F.A. / Gander, Bruno --$t3.3. Peptide Based Vaccines /$rSchild, Hansjörg / Rammensee, Hans-Georg --$t3.4. Recombinant Bacteria as Vaccine Carriers of Heterologous Antigens /$rHormaeche, Carlos E. / Khan, C. M. Anjam --$t3.5. Genetic Detoxification of Bacterial Toxins /$rRappuoli, Rino / Pizza, Mariagrazia --$t3.6. Recombinant Virus as Vaccination Carrier of Heterologous Antigens /$rPerkus, Marion E. / Paoletti, Enzo --$t3.7. Naked DNA Vaccination /$rShiver, John W. / Ulmer, Jeffrey B. / Donnelly, John J. / Liu, Margaret A. --$t3.8. Oral Vaccination, Mucosal Immunity and Oral Tolerance with Special Reference to Cholera Toxin /$rHolmgren, Jan / Czerkinsky, Cecil / Sun, Jia-Bin / Svennerholm, Ann-Mari --$t4. Specific Vaccination Strategies --$t4.1. Helicobacter pylori: Pathogenic Determinants and Strategies for Vaccine Design /$rGhiara, Paolo / Covacci, Antonello / Telford, John L. / Rappuoli, Rino --$t4.2. Malaria Vaccination /$rPatarroyo, Manuel E. / Amador, Roberto --$t4.3. Vaccination Against Schistosomiasis: Concepts and Strategies /$rRiveau, Gilles J. / Capron, André --$t4.4. AIDS Vaccination /$rNorley, Stephen / Kurth, Reinhard --$t4.5. Vaccination Therapy Against Autoimmune Diseases /$rCohen, Irun R. / Mor, Felix --$tContributors --$tIndex 606 $aVaccines 606 $aImmunization 615 0$aVaccines. 615 0$aImmunization. 676 $a615/.372 686 $aXD 3300$2rvk 701 $aKaufmann$b S. H. E$g(Stefan H. E.)$042605 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910815140603321 996 $aConcepts in vaccine development$93925731 997 $aUNINA