LEADER 05659nam 2200757 a 450 001 9910815012703321 005 20240516114921.0 010 $a9786613639912 010 $a9783527645176 010 $a3527645179 010 $a9781280662980 010 $a1280662980 010 $a9783527645206 010 $a3527645209 010 $a9783527645183 010 $a3527645187 035 $a(CKB)2550000000083742 035 $a(EBL)849024 035 $a(OCoLC)775302062 035 $a(SSID)ssj0000636964 035 $a(PQKBManifestationID)11458229 035 $a(PQKBTitleCode)TC0000636964 035 $a(PQKBWorkID)10678767 035 $a(PQKB)11595528 035 $a(MiAaPQ)EBC849024 035 $a(Au-PeEL)EBL849024 035 $a(CaPaEBR)ebr10529305 035 $a(CaONFJC)MIL363991 035 $a(PPN)168392054 035 $a(Perlego)1012684 035 $a(EXLCZ)992550000000083742 100 $a20120218d2012 uy 0 101 0 $aeng 135 $aurcn||||||||| 181 $ctxt 182 $cc 183 $acr 200 00$aIndustrial crystallization process monitoring and control /$fedited by Angelo Chianese and Herman J. M. Kramer 205 $a1st ed. 210 $aWeinheim, Germany $cWiley-VCH$d2012 215 $a1 online resource (253 p.) 300 $aDescription based upon print version of record. 311 08$a9783527331734 311 08$a3527331735 320 $aIncludes bibliographical references and index. 327 $aIndustrial Crystallization Process Monitoring and Control; Contents; Preface; Scope of the Book; List of Contributors; 1 Characterization of Crystal Size Distribution; 1.1 Introduction; 1.2 Particle Size Distribution; 1.3 Particle Size Distribution Moments; 1.4 Particle Size Distribution Characterization on the Basis of Mass Distribution; References; 2 Forward Light Scattering; 2.1 Introduction; 2.2 Principles of Laser Diffraction; 2.3 Scatter Theory; 2.3.1 Generalized Lorenz-Mie Theory; 2.3.2 Anomalous Diffraction; 2.3.3 Fraunhofer Diffraction; 2.4 Deconvolution 327 $a2.4.1 Direct Inversion Using the Nonnegativity Constraint 2.4.2 Philips Twomey Inversion Method; 2.4.3 Iterative Methods; 2.5 The Effects of Shape; 2.6 Multiple Scattering; 2.7 Application of Laser Diffraction for Monitoring and Control of Industrial Crystallization Processes; 2.8 Conclusions; References; Further Reading; 3 Focused Beam Reflectance Measurement; 3.1 Measurement Principle; 3.2 Application Examples; 3.2.1 Solubility and Metastable Zone Width (MSZW); 3.2.2 Seed Effectiveness; 3.2.3 Polymorph Transformations; 3.2.4 Effect of Different Impurity Levels; 3.2.5 Nucleation Kinetics 327 $a3.2.6 Improved Downstream Processing 3.2.7 Process Control; 3.3 Advantages and Limitations; References; 4 Turbidimetry for the Estimation of Crystal Average Size; 4.1 Introduction; 4.2 Determination of Average Particle Size from Specific Turbidity; 4.3 Procedure to Evaluate Average Crystal Size by Turbidimetry for a High Solid Slurry Concentration; 4.4 Conclusion; References; Further Reading; 5 Imaging; 5.1 Introduction; 5.2 Literature Overview; 5.3 The Sensor Design; 5.3.1 Optics and Illumination; 5.3.2 The Camera System and the Resolution; 5.3.3 Image Analysis; 5.3.4 Statistics 327 $a5.4 Application of In Situ Imaging for Monitoring Crystallization Processes 5.4.1 Example 1; 5.4.2 Example 2; 5.5 Conclusions; References; Further Reading; 6 Turbidimetry and Nephelometry; 6.1 Introduction; 6.2 Measurement of Nucleation and Solubility Points; 6.3 The Developed Turbidimetric and Nephelometric Instruments; 6.4 The Examined Systems; 6.5 Obtained Results; References; 7 Speed of Sound; 7.1 Introduction; 7.2 In-Process Ultrasound Measurement; 7.3 Determining Solubility and Metastable Zone Width; 7.4 Measuring Crystal Growth Rates; 7.5 Detecting Phase Transitions with Ultrasound 327 $aReferences 8 In-Line Process Refractometer for Concentration Measurement in Sugar Crystallizers; 8.1 Introduction; 8.2 Measurement Principle; 8.3 In-Line Instrument Features and Benefits; 8.3.1 Accuracy; 8.3.2 Concentration Determination; 8.3.3 Process Temperature Compensation Factor; 8.3.4 Process Sensor; 8.4 Features and Benefits; 8.5 Example of Application in the Crystallization; 8.5.1 Seeding Point and Supersaturation Control in Sugar Vacuum Pan; 8.6 Conclusion; References; 9 ATR-FTIR Spectroscopy; 9.1 Introduction; 9.2 Calibration; 9.3 Speciation Monitoring; 9.4 Co-Crystal Formation 327 $a9.5 Solubility Measurement 330 $aCrystallization is an important technique for separation and purification of substances as well as for product design in chemical, pharmaceutical and biotechnological process industries. This ready reference and handbook draws on research work and industrial practice of a large group of experts in the various areas of industrial crystallization processes, capturing the essence of current trends, the markets, design tools and technologies in this key field. Along the way, it outlines trouble free production, provides laboratory controls, analyses case studies and discusses new ch 606 $aCrystallization$xIndustrial applications 606 $aCrystallization 615 0$aCrystallization$xIndustrial applications. 615 0$aCrystallization. 676 $a660.284298 701 $aChianese$b Angelo$07917 701 $aKramer$b Herman J. M$01625849 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910815012703321 996 $aIndustrial crystallization process monitoring and control$93961566 997 $aUNINA