LEADER 02830nam 2200661 a 450 001 9910813588703321 005 20240313183816.0 010 $a3-527-67040-8 010 $a3-527-67038-6 010 $a1-299-40220-8 010 $a3-527-67039-4 035 $a(CKB)2550000001017928 035 $a(EBL)1157730 035 $a(OCoLC)833767002 035 $a(SSID)ssj0000904913 035 $a(PQKBManifestationID)11494291 035 $a(PQKBTitleCode)TC0000904913 035 $a(PQKBWorkID)10941255 035 $a(PQKB)10801533 035 $a(MiAaPQ)EBC1157730 035 $a(MiAaPQ)EBC4044500 035 $a(Au-PeEL)EBL1157730 035 $a(CaPaEBR)ebr10677831 035 $a(CaONFJC)MIL471470 035 $a(PPN)194570274 035 $a(EXLCZ)992550000001017928 100 $a20130403d2013 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aTrypanosomatid diseases $emolecular routes to drug discovery /$fedited by Timo Ja?ger, Oliver Koch, and Leopold Flohe? 205 $a1st ed. 210 $aWeinheim $cWiley-VCH$d2013 215 $a1 online resource (578 p.) 225 1 $aDrug discovery in infectious diseases ;$vv. 4 300 $aDescription based upon print version of record. 311 $a3-527-33255-3 320 $aIncludes bibliographical references and index. 327 $apt. 1. Disease burden, current treatments, medical needs, and strategic approaches -- pt. 2. Metabolic peculiarities in the trypanosomatid family guiding drug discovery -- pt. 3. Validation and selection of drug targets in kinetoplasts -- pt. 4. Examples of target-based approaches and compounds under consideration. 330 $aThis is the first resource to provide researchers in academia and industry with an urgently needed update summarizing the current knowledge and possibilities for drug intervention against Trypanosomatides all in one volume. As such, it covers every aspect of the topic from basic research findings, via current treatments to translational approaches in drug development and includes both human and livestock diseases. The outstanding editor and contributor team reads like a Who?s Who of the field, thus guaranteeing the outstanding quality of this ready reference. 410 0$aDrug discovery in infectious diseases ;$vv. 4. 606 $aParasitic diseases 606 $aTrypanosomatidae 615 0$aParasitic diseases. 615 0$aTrypanosomatidae. 676 $a616.936061 701 $aJa?ger$b Timo$01618464 701 $aKoch$b Oliver$01618465 701 $aFlohe?$b Leopold$01618466 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910813588703321 996 $aTrypanosomatid diseases$93950201 997 $aUNINA