LEADER 05423nam 2200673 450 001 9910813257303321 005 20200520144314.0 010 $a0-323-35303-7 035 $a(CKB)3710000000331146 035 $a(EBL)1913317 035 $a(SSID)ssj0001435326 035 $a(PQKBManifestationID)11883602 035 $a(PQKBTitleCode)TC0001435326 035 $a(PQKBWorkID)11429503 035 $a(PQKB)10334603 035 $a(Au-PeEL)EBL1913317 035 $a(CaPaEBR)ebr11001787 035 $a(CaONFJC)MIL688890 035 $a(OCoLC)899739224 035 $a(MiAaPQ)EBC1913317 035 $a(EXLCZ)993710000000331146 100 $a20150114h20152015 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aNanotechnology applications for tissue engineering /$fedited by Sabu Thomas, Yves Grohens, Neethu Ninan 210 1$aOxford, England ;$aWaltham, Massachusetts :$cWilliam Andrew,$d2015. 210 4$dİ2015 215 $a1 online resource (336 p.) 225 1 $aMicro & Nano Technologies Series 300 $aDescription based upon print version of record. 311 $a1-322-57608-4 311 $a0-323-32889-X 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $aFront Cover; Nanotechnology Applications for Tissue Engineering; Copyright Page; Contents; List of Contributors; About the Editors; Preface; 1 Nanomedicine and Tissue Engineering; 1.1 Introduction; 1.1.1 Nanomedicine; 1.1.2 Tissue Engineering; 1.2 Relationship of Nanomedicine and Tissue Engineering; 1.2.1 Nanomedicine Approaches in Bone Tissue Engineering; 1.2.2 Nanomedicine Approaches in Cardiac Tissue Engineering; 1.2.3 Nanomedicine Approaches in Skin Tissue Engineering; 1.2.4 Nanomedicine Approaches in Brain Tissue Engineering 327 $a1.2.5 Nanomedicine Approaches for Other Tissue Engineering Disciplines1.3 Nanodrug Delivery Systems for Tissue Regeneration; 1.3.1 Nanotheranostics; 1.3.2 Nanoregeneration Medicine; 1.3.3 Nanodrug Delivery; 1.3.3.1 Dendrimers; 1.3.3.2 Liposomes; 1.3.3.3 Carbon Nanotubes; 1.3.3.4 Nanocomposite Hydrogel; 1.4 Medical Applications of Molecular Nanotechnology; 1.4.1 Nanorobots; 1.4.2 Cell Repair Machines; 1.5 Summary and Future Directions; References; 2 Biomaterials: Design, Development and Biomedical Applications; 2.1 Overview; 2.2 Design of Biomaterials; 2.2.1 Polymers; 2.2.2 Metals 327 $a2.2.3 Composite Materials2.2.4 Ceramics; 2.3 Basic Considerations to Design Biomaterial; 2.4 Characteristics of Biomaterials; 2.4.1 Nontoxicity; 2.4.2 Biocompatible; 2.4.3 Absence of Foreign Body Reaction; 2.4.4 Mechanical Properties and Performance; 2.5 Fundamental Aspects of Tissue Responses to Biomaterials; 2.5.1 Injury; 2.5.2 Blood-Material Interactions and Initiation of the Inflammatory Response; 2.5.3 Provisional Matrix Formation; 2.5.4 Acute Inflammation; 2.5.5 Chronic Inflammation; 2.5.6 Granulation Tissue; 2.5.7 Foreign Body Reaction; 2.5.8 Fibrosis and Fibrous Encapsulation 327 $a2.6 Evaluation of Biomaterial Behavior2.6.1 Assessment of Physical Properties; 2.6.2 In vitro Assessment; 2.6.3 In vivo Assessment; 2.7 Properties of Biomaterials Assessed Through In Vivo Experiments; 2.7.1 Sensitization, Irritation, and Intracutaneous Reactivity; 2.7.2 Systemic, Subacute, and Subchronic Toxicity; 2.7.3 Genotoxicity; 2.7.4 Implantation; 2.7.5 Hemocompatibility; 2.7.6 Chronic Toxicity; 2.7.7 Carcinogenicity; 2.7.8 Reproductive and Developmental Toxicity; 2.7.9 Biodegradation; 2.7.10 Immune Responses; 2.8 Applications of Biomaterials; 2.8.1 Orthopedic Applications 327 $a2.8.2 Ophthalmologic Applications2.8.3 Cardiovascular Applications; 2.8.4 Dental Applications; 2.8.5 Wound Dressing Applications; 2.8.6 Other Applications; 2.9 Future Directions in Biomaterials; 2.10 Conclusions; Acknowledgments; References; 3 Electrospinning of Polymers for Tissue Engineering; 3.1 Introduction; 3.2 History of Electrospinning; 3.3 Experimental Setup and Basic Principle; 3.3.1 Theoretical Background; 3.4 Effects of Parameters on Electrospinning; 3.4.1 Solution Parameters; 3.4.2 Concentration and Viscosity; 3.4.3 Molecular Weight; 3.4.4 Surface Tension 327 $a3.4.5 Conductivity of the Solution 330 $a Tissue engineering involves seeding of cells on bio-mimicked scaffolds providing adhesive surfaces. Researchers though face a range of problems in generating tissue which can be circumvented by employing nanotechnology. It provides substrates for cell adhesion and proliferation and agents for cell growth and can be used to create nanostructures and nanoparticles to aid the engineering of different types of tissue. Written by renowned scientists from academia and industry, this book covers the recent developments, trends and innovations in the application of nanotechnologies in tissue engineer 410 0$aMicro & nano technologies. 606 $aTissue engineering 606 $aNanotechnology 615 0$aTissue engineering. 615 0$aNanotechnology. 676 $a610.28 702 $aThomas$b Sabu 702 $aGrohens$b Yves 702 $aNinan$b Neethu 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910813257303321 996 $aNanotechnology applications for tissue engineering$93924778 997 $aUNINA