LEADER 04104nam 2200673 a 450 001 9910813138703321 005 20200520144314.0 010 $a1-280-84154-0 010 $a9786610841547 010 $a92-4-068194-9 035 $a(CKB)1000000000334689 035 $a(SSID)ssj0000083634 035 $a(PQKBManifestationID)11120585 035 $a(PQKBTitleCode)TC0000083634 035 $a(PQKBWorkID)10162807 035 $a(PQKB)11247257 035 $a(MiAaPQ)EBC286833 035 $a(Au-PeEL)EBL286833 035 $a(CaPaEBR)ebr10161462 035 $a(CaONFJC)MIL84154 035 $a(OCoLC)476039042 035 $a(EXLCZ)991000000000334689 100 $a20081017d2006 uy 0 101 0 $aeng 135 $aurcn||||||||| 181 $ctxt 182 $cc 183 $acr 200 10$aEvaluation of certain veterinary drug residues in food $esixty-sixth report of the Joint FAO/WHO Expert Committee on Food Additives 205 $a1st ed. 210 $aGeneva $cWorld Health Organization$d2006 215 $avi, 80 p 225 1 $aWHO technical report series,$x0512-3054 ;$v939 300 $aBibliographic Level Mode of Issuance: Monograph 311 $a92-4-120939-9 320 $aIncludes bibliographical references. 327 $aIntro -- Contents -- Introduction -- General considerations -- Comments on residues of specific veterinary drugs -- Future work -- Recommendations -- Acknowledgement -- References -- Reports and other documents resulting from previous meetings of the Joint FAO/WHO Expert Committee on Food Additives -- Recommendations on compounds on the agenda and further information required. 330 $aThis report represents the conclusions of a Joint FAO/WHO Expert Committee convened to evaluate the safety of residues of certain veterinary drugs in food and to recommend maximum levels for such residues in food. The first part of the report considers general principles regarding the evaluation of veterinary drugs within the terms of reference of JECFA, including compounds without an ADI or MRL; recommendations on principles and methods in derivation of MRLs, including a new procedure for estimating chronic dietary intakes; the use of a spreadsheet-based procedure for the statistical evaluation of residue depletion data; a revised approach for the derivation of microbiological ADIs; and the Committee's review of and comments on documents provided by the Codex Committee on Residues of Veterinary Drugs. Summaries follow of the Committee's evaluations of toxicological and residue data on a variety of veterinary drugs: three antimicrobial agents (colistin, erythromycin, flumequine), two production aids (melengestrol acetate, ractopamine hydrochloride, an insecticide (trichlorfon (metrifonate)), and an anthelminthic (triclabendazole). In addition, the attempt by the Committee to use tylosin as an example to investigate if evaluations are possible based on published data in the absence of data submissions from sponsors is described. Annexed to the report is a summary of the Committee's recommendations on these drugs, including acceptable daily intakes and proposed maximum residue limits. 410 0$aTechnical report series (World Health Organization) ;$v939. 517 3 $a66th report of the Joint FAO/WHO Expert Committee on Food Additives 517 3 $aSixty-sixth report of the Joint FAO/WHO Expert Committee on Food Additives 606 $aVeterinary drug residues$vCongresses 606 $aFood additives$vCongresses 606 $aVeterinary drugs$vCongresses 606 $aFood contamination$vCongresses 615 0$aVeterinary drug residues 615 0$aFood additives 615 0$aVeterinary drugs 615 0$aFood contamination 676 $a664.06 712 02$aWorld Health Organization. 712 02$aFood and Agriculture Organization of the United Nations. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910813138703321 996 $aEvaluation of certain veterinary drug residues in food$91940650 997 $aUNINA