LEADER 03599nam 2200613 450 001 9910812874103321 005 20230803201931.0 010 $a1-118-39626-X 010 $a1-118-39629-4 010 $a1-118-39627-8 035 $a(CKB)3710000000093473 035 $a(EBL)1650820 035 $a(SSID)ssj0001132598 035 $a(PQKBManifestationID)11592085 035 $a(PQKBTitleCode)TC0001132598 035 $a(PQKBWorkID)11154812 035 $a(PQKB)11292197 035 $a(MiAaPQ)EBC4388567 035 $a(DLC) 2014001135 035 $a(MiAaPQ)EBC1650820 035 $a(Au-PeEL)EBL1650820 035 $a(CaPaEBR)ebr10849275 035 $a(OCoLC)868150760 035 $a(EXLCZ)993710000000093473 100 $a20140327h20142014 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aMolecular aspects of aging $eunderstanding lung aging /$fedited by Mauricio Rojas, Silke Meiners, Claude Jourdan LeSaux 210 1$aHoboken, New Jersey :$cWiley-Blackwell,$d2014. 210 4$dİ2014 215 $a1 online resource (231 p.) 300 $aDescription based upon print version of record. 311 $a1-118-39624-3 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $aThe demography of aging / David E. Bloom and Sinead Shannon -- The "OMICS" of aging : insights from genomes upon stress / Ismene Karakasilioti, Anna Ioannidou, and George A. Garinis -- Protein quality control coming of age / Silke Meiners -- Telomerase function in aging / Rodrigo T. Calado -- The cellular senescence progtam / Pooja Shivshankar and Claude Jourdan Lesaux -- Signaling networks controlling cellular senescence / Leena P. Desar, Yan Y. Sanders, and Victor J. Thannickal -- Immune senescence / Kevin P. High -- Developmental and physiological aging of the lung / Kent E. Pinkerton, Lei Wang, Suzette M. Smiley-Jewell, Jingyi Xu, and Francis H. Y. Green -- Mouse models to explore the aging lung / Mingyi Wang and Deepak A. Deshpande -- Evidence for premature lung aging of the injured neonatal lung as exemplified by bronchopulmonary dysplasia / Anne Hilgenderff -- Remodeling of the extracellular matrix in the aging lung / Jesse Roman -- Aging Mesenchymal Stem Cells in lung disease / Maria G. Kapetanaki, Ana L. Mora, and Mauricio Rojas -- COPD as a disease of premature aging / Laurent Boyer, Jorge Boczkowski, and Serge Adnot -- Lung infections and aging / Jacqueline M. Kehler and Keith C. Meyer. 330 $aMolecular Aspects of Aging: Understanding Lung Aging covers recent research in the mechanisms that contribute to cellular senescence. Covering universal themes in aging, such as the exhaustion of stem cells and subsequent loss of the regenerative refueling of organs as well as immunosenescence, this text illuminates new directions for research not yet explored in the still poorly investigated area of molecular mechanisms of lung aging. The molecular nature of general aging processes is explored with targeted coverage on how to analyze lung aging through experimental approaches. 606 $aAging$xPhysiology 606 $aLungs$xDiseases 615 0$aAging$xPhysiology. 615 0$aLungs$xDiseases. 676 $a612.6/7 702 $aRojas$b Mauricio$f1963- 702 $aMeiners$b Silke 702 $aLe Saux$b Claude Jourdan 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910812874103321 996 $aMolecular aspects of aging$94125620 997 $aUNINA