LEADER 02601nam 2200637 450 001 9910812853803321 005 20200520144314.0 010 $a1-77112-165-3 010 $a1-77112-164-5 035 $a(CKB)3710000000752663 035 $a(EBL)4530378 035 $a(OOCEL)468002 035 $a(OCoLC)949989572 035 $a(CaBNVSL)kck00236829 035 $a(MiAaPQ)EBC4530378 035 $a(OCoLC)915264071 035 $a(MdBmJHUP)muse55366 035 $a(Au-PeEL)EBL4530378 035 $a(CaPaEBR)ebr11213073 035 $a(CaONFJC)MIL923031 035 $a(PPN)250538717 035 $a(EXLCZ)993710000000752663 100 $a20150730d2016 uy 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 181 $2rdacontent 182 $2rdamedia 183 $2rdacarrier 200 10$aHuman rights in Canada $ea history /$fDominique Cle?ment 210 1$aWaterloo, Ontario :$cWilfrid Laurier University Press,$d[2016] 210 4$d©2016 210 2$aOttawa, Ontario :$cCanadian Electronic Library,$d2016. 215 $a1 online resource (247 p.) 225 1 $aLaurier studies in political philosophy 300 $aIssued as part of the Canadian Electronic Library. Canadian publishers collection. 311 $a1-77112-163-7 320 $aIncludes bibliographical references (pages 199-217) and index. 327 $aIntroduction -- CHAPTER 1 Liberty and State Formation -- CHAPTER 2 Civil Liberties in Canada -- CHAPTER 3 Human Rights Beginnings -- CHAPTER 4 The Rights Revolution -- CHAPTER 5 Contesting Human Rights -- Conclusion. 330 $aThis book shows how human rights became the primary language for social change in Canada and how a single decade became the locus for that emergence. The author argues that the 1970s was a critical moment in human rights history one that transformed political culture, social movements, law, and foreign policy. 410 0$aLaurier studies in political philosophy series. 606 $aHuman rights$zCanada$xHistory 606 $aHuman rights$xSocial aspects$zCanada 606 $aDroits de l'homme (Droit international)$zCanada$xHistoire 608 $aLibros electronicos. 615 0$aHuman rights$xHistory. 615 0$aHuman rights$xSocial aspects 615 6$aDroits de l'homme (Droit international)$xHistoire. 676 $a323.0971 700 $aCle?ment$b Dominique$f1975-$01697687 801 0$bFINmELB 801 1$bFINmELB 906 $aBOOK 912 $a9910812853803321 996 $aHuman rights in Canada$94078593 997 $aUNINA LEADER 05292nam 22007575 450 001 9910555236203321 005 20251009100824.0 010 $a3-030-92612-5 024 7 $a10.1007/978-3-030-92612-0 035 $a(CKB)5860000000038032 035 $aEBL6942718 035 $a(AU-PeEL)EBL6942718 035 $a(MiAaPQ)EBC6942718 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/81445 035 $a(ODN)ODN0010072617 035 $a(oapen)doab81445 035 $a(DE-He213)978-3-030-92612-0 035 $a(EXLCZ)995860000000038032 100 $a20220329d2022 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aPrecision Oncology and Cancer Biomarkers $eIssues at Stake and Matters of Concern /$fedited by Anne Bremer, Roger Strand 205 $a1st ed. 2022. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2022. 215 $a1 online resource (288 p.) 225 1 $aHuman Perspectives in Health Sciences and Technology,$x2661-8923 ;$v5 300 $aDescription based upon print version of record. 311 08$a3-030-92611-7 320 $aIncludes bibliographical references and index. 327 $aIntroduction (Anne Bremer and Roger Strand) -- Chapter 1. Precision oncology in the news (Mille Stenmarck and Irmelin Nilsen) -- Chapter 2. Cancer biomarkers from a patient?s perspective (Karen Gissum) -- Chapter 3. Breast cancer: reconstruction of trouble (Hanna Dillekås) -- Chapter 4. HER2: an apparently ?simple? biomarkers revealing the complexities and uncertainties of precision oncology (Elisabeth Wik, Anne Bremer and Lars A. Akslen) -- Chapter 5. Integrating genomic and non-genomic factors in shaping the personal fingerprint in personalised cancer treatments (Mariano Bizzari and Andrea Pensotti) -- Chapter 6. Systems medicine and perspectives on precision oncology (Rune Kleppe, Inge Jonassen and Roger Strand) -- Chapter 7. Precision oncology: the challenges related to publishing (Maria Lie Lotsberg) -- Chapter 8. Filled with Desire, Perceive Molecules (Caroline Engen and Roger Strand) -- Chapter 9. Precision health and ethical ambiguity: How much cancer can we afford to prevent? (Leonard Fleck) -- Chapter 10. New cancer drugs and the public controversy: how can biomarkers contribute? (Eirik Tranvåg and Roger Strand) -- Chapter 11. Assessing the cost-effectiveness of targeted therapies and checkpoint inhibitors (John Cairns) -- Chapter 12. Real-world data in Health Technology Assessment of targeted cancer therapy (Jiyeon Kang) -- Chapter 13. Negotiating safety and resources in a first in human cancer trial in Denmark (Line Hillersdal) -- Conclusion: Precision oncology: Fact or fantasy? (Roger Strand and Anne Bremer). 330 $aThis open access book reflects on matters of social and ethical concern raised in the daily practices of those working in and around precision oncology. Each chapter addresses the experiences, concerns and issues at stake for people who work in settings where precision oncology is practiced, enacted, imagined or discussed. It subsequently discusses and analyses bioethical dilemmas, scientific challenges and economic trade-offs, the need for new policies, further technological innovation, social work, as well as phenomenological research. This volume takes a broad actor-centred perspective as, whenever cancer is present, the range of actors with issues at stake appears almost unlimited. This perspective and approach opens up the possibility for further in-depth and diverse questions, posed by the actors themselves, such as: How are cancer researchers navigating biological uncertainties? How do clinicians and policy-makers address ethical dilemmas around prioritisation ofcare? What are the patients? experiences with, and hopes for, precision oncology? How do policy-makers and entrepreneurs envisage precision oncology? These questions are of great interest to a broad audience, including cancer researchers, oncologists, policy-makers, medical ethicists and philosophers, social scientists, patients and health economists. 410 0$aHuman Perspectives in Health Sciences and Technology,$x2661-8923 ;$v5 606 $aMedicine$xPhilosophy 606 $aBioethics 606 $aCancer 606 $aPublic health 606 $aMedical economics 606 $aPhilosophy of Medicine 606 $aBioethics 606 $aCancer Biology 606 $aPublic Health 606 $aHealth Economics 615 0$aMedicine$xPhilosophy. 615 0$aBioethics. 615 0$aCancer. 615 0$aPublic health. 615 0$aMedical economics. 615 14$aPhilosophy of Medicine. 615 24$aBioethics. 615 24$aCancer Biology. 615 24$aPublic Health. 615 24$aHealth Economics. 676 $a610.1 686 $aBUS069000$aMED050000$aMED062000$aMED078000$aPHI005000$2bisacsh 700 $aBremer$b Anne$01236572 701 $aStrand$b Roger$01236573 801 0$bAU-PeEL 801 1$bAU-PeEL 801 2$bAU-PeEL 906 $aBOOK 912 $a9910555236203321 996 $aPrecision Oncology and Cancer Biomarkers$92871217 997 $aUNINA