LEADER 04218oam 2200625I 450 001 9910812847603321 005 20230803203032.0 010 $a1-77463-083-4 010 $a0-429-17184-6 010 $a1-4822-9945-3 024 7 $a10.1201/b17138 035 $a(CKB)3710000000128930 035 $a(EBL)1686709 035 $a(SSID)ssj0001285980 035 $a(PQKBManifestationID)11858560 035 $a(PQKBTitleCode)TC0001285980 035 $a(PQKBWorkID)11265438 035 $a(PQKB)10438600 035 $a(OCoLC)881463216 035 $a(MiAaPQ)EBC1686709 035 $a(EXLCZ)993710000000128930 100 $a20180331h20142014 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aCancer cell signaling $etargeting signaling pathways toward therapeutic approaches to cancer /$fedited by Kasirajan Ayyanathan, PhD 205 $aFirst edition. 210 1$aWaretown, NJ :$cApple Academic Press, Inc. ;$aBoca Raton, FL :$cCRC Press,$d[2014] 210 4$d©2014 215 $a1 online resource (402 p.) 300 $aDescription based upon print version of record. 311 $a1-322-63805-5 311 $a1-77188-067-8 320 $aIncludes bibliographical references at the end of each chapters. 327 $aFront Cover; About the Editor; Contents; Acknowledgment and How to Cite; List of Contributors; Introduction; Chapter 1: TGFß-Mediated Suppression of CD248 in Non-Cancer Cells via Canonical SMAD-Dependent Signaling Pathways is Uncoupled in Cancer Cells; Chapter 2: Graded Inhibition of Oncogenic Ras-Signaling by Multivalent Ras-Binding Domains; Chapter 3: Direct Inhibition of PI3K in Combination with Dual HER2 Inhibitors is Required for Optimal Antitumor Activity in HER2+ Breast Cancer Cells 327 $aChapter 4: Wnt3a Expression is Associated with MMP-9 Expression in Primary Tumor and Metastatic Site in Recurrent or Stage IV Colorectal CancerChapter 5: Wnt5a Promotes Migration of Human Osteosarcoma Cells by Triggering a Phosphatidylinositol-3 Kinase/Akt Signals; Chapter 6: FOXA1 Promotes Tumor Cell Proliferation through AR Involving the Notch Pathway in Endometrial Cancer; Chapter 7: PKC ? Regulates Netrin-1/UNC5B-Mediated Survival Pathway in Bladder Cancer; Chapter 8: Signaling Pathways in the Development of Infantile Hemangioma 327 $aChapter 9: STAG2 is a Clinically Relevant Tumor Suppressor in Pancreatic Ductal AdenocarcinomaChapter 10: Molecular Determinants of Context-Dependent Progesterone Receptor Action in Breast Cancer; Chapter 11: Architecture of Epigenetic Reprogramming Following Twist1-Mediated Epithelial-Mesenchymal Transition; Chapter 12: Stability and Prognostic Value of Slug, Sox9, and Sox10 Expression in Breast Cancers Treated with Neoadjuvant Chemotherapy 327 $aChapter 13: Combination Therapy of Anti-Cancer Bioactive Peptide with Cisplatin Decreases Chemotherapy Dosing and Toxicity to Improve the Quality of Life in Xenograft Nude Mice Bearing Human Gastric CancerChapter 14: Combination of Sulindac and Dichloroacetate Kills Cancer Cells via Oxidative Damage; Author Notes 330 $aCell signaling is a field that studies how cells communicate to control basic activities and respond to their environment. When looking specifically at cancer cells, researchers can gain a better understanding of cancer on a cellular level, an understanding that may have implications for developing new treatments. The current volume provides an overview of the field and how various cell biology techniques are used to better understand cancer on a cellular level. This easily accessible reference volume offers a comprehensive look at the field of cancer cell signaling. Edited by a researcher 606 $aCancer cells 606 $aCellular signal transduction 606 $aCancer$xTreatment 615 0$aCancer cells. 615 0$aCellular signal transduction. 615 0$aCancer$xTreatment. 676 $a616.99/407 702 $aAyyanathan$b Kasirajan 801 0$bFlBoTFG 801 1$bFlBoTFG 906 $aBOOK 912 $a9910812847603321 996 $aCancer cell signaling$93985960 997 $aUNINA